公开(公告)号：US6128366A

公开(公告)日：2000-10-03

申请号：US112073

申请日：1998-07-08

Applicant: Ramon Alfredo Siochi

Inventor： Ramon Alfredo Siochi

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1042 ,  Y10S378/901

Abstract: A radiation therapy delivery and dosimetry error correction system. Rather than iteratively creating more segments to correct for dosimetry errors, the present invention receives the outputs from a segment optimization algorithm (i.e., a set of segments and an initial set of monitor units) and varies the number of monitor units associated with each segment to correct for dosimetry errors. Only if an extreme case exists will additional segments be added.

Abstract translation: 放射治疗递送和剂量学误差校正系统。 本发明不是迭代地创建更多的片段来校正剂量测量误差，而是从片段优化算法（即，一组片段和初始的一组监视器单元）接收输出，并且将与每个片段相关联的监视器单元的数量改变为 校正剂量误差。 只有存在极端情况，才能添加其他细分。

公开(公告)号：US06240161B1

公开(公告)日：2001-05-29

申请号：US08936299

申请日：1997-09-25

Applicant: Ramon Alfredo Siochi

Inventor： Ramon Alfredo Siochi

IPC: G21K508

CPC classification number: A61N5/1042 ,  A61N5/1036

Abstract: A system and method for radiation therapy delivery. The present invention provides for optimizing radiation delivery by accounting for the physical attributes of a beam shielding device (401) when determining an optimal radiation treatment. These include, for example, constraining the optimization engine with realizable positioning of plates and/or collimator leaves. Thus, an optimal set of fields and intensity levels for those fields are chosen.

Abstract translation: 放射治疗递送的系统和方法。 本发明通过在确定最佳辐射治疗时考虑束屏蔽装置（401）的物理属性来提供优化辐射传递。 这些包括例如限制优化引擎与板和/或准直器叶的可实现的定位。 因此，选择这些领域的最佳的一组场和强度水平。

公开(公告)号：US6134296A

公开(公告)日：2000-10-17

申请号：US234364

申请日：1999-01-20

Applicant: Ramon Alfredo Siochi

Inventor： Ramon Alfredo Siochi

IPC: A61N5/10 ,  G21K1/04

CPC classification number: A61N5/1042 ,  G21K1/046 ,  Y10S378/901

Abstract: The present invention provides for delivering two one (1) centimeter by point five (0.5) centimeter intensity maps that are orthogonal to each other so as to generate microgradients within each one centimeter by one centimeter square. Thus, an effective intensity map grid size is point five centimeters by point five centimeters.

Abstract translation: 本发明提供递送两个彼此正交的五点（0.5厘米）厘米的强度图，以便在每一厘米乘以一厘米2平方厘米的范围内产生微观梯度。 因此，有效强度地图网格大小是五厘米到五厘米。

公开(公告)号：US6052430A

公开(公告)日：2000-04-18

申请号：US937829

申请日：1997-09-25

Applicant: Ramon Alfredo Siochi ,  John Hughes

Inventor： Ramon Alfredo Siochi ,  John Hughes

IPC: G21K1/02 ,  A61N5/10 ,  G21K1/04

CPC classification number: A61N5/1042 ,  G21K1/04 ,  G21K1/046

Abstract: A system and method for dynamic subspace intensity modulation. Portions around the edges of a multi-leaf collimator-defined static radiation field are expanded or shrunk during part or all of the delivery of radiation at constant velocity. In order to match some or all of the sloping regions (502) of an intensity profile, the individual leaves (41, 42) of the multi-leaf collimator are moved at a fixed velocity over the sloping portions (502) of the intensity profile. By keeping the major portion of the field static and by only moving the leaves at one fixed velocity over a small subspace of the intensity profile, it is relatively easier to know what dose the patient receives and it is also relatively easier to resume treatment since it can be determined exactly how many more monitor units of radiation must be delivered and what the leaf positions were when the radiation was turned off.

Abstract translation: 一种用于动态子空间强度调制的系统和方法。 在多叶准直器定义的静态辐射场的边缘周围的部分在部分或全部以恒定速度传送的辐射下被扩展或收缩。 为了匹配强度分布的部分或全部倾斜区域（502），多叶准直器的单个叶片（41,42）以固定的速度移动到强度分布的倾斜部分（502）上 。 通过将场的主要部分保持静止，并且仅通过在强度分布的小子空间上以一个固定的速度移动叶子，相对更容易知道患者接受的剂量，并且因为它更容易恢复治疗 可以确定在辐射被关闭时必须传送多少个监视器的辐射单位和叶片的位置。