公开(公告)号：US12064647B2

公开(公告)日：2024-08-20

申请号：US17361817

申请日：2021-06-29

Applicant: Siemens Healthineers International AG

Inventor： Marko T. Rusanen ,  Jarkko Y. Peltola ,  Shahab Basiri ,  Esa Kuusela

IPC: A61N5/10 ,  G05B13/02 ,  G06N3/09 ,  G06N3/092 ,  G16H20/40 ,  G16H40/63 ,  G16H50/20 ,  G16H50/70

CPC classification number: A61N5/1036 ,  A61N5/1031 ,  A61N5/1045 ,  G05B13/027 ,  G06N3/09 ,  G06N3/092 ,  G16H20/40 ,  G16H40/63 ,  G16H50/20 ,  G16H50/70

Abstract: A memory has a fluence map that corresponds to a particular patient stored therein. This memory also has at least one deep learning model stored therein trained to deduce a leaf sequence for a multi-leaf collimator from a fluence map. A control circuit operably coupled to that memory iteratively optimizes a radiation treatment plan to administer therapeutic radiation to that patient by, at least in part, generating a leaf sequence as a function of the at least one deep learning model and the fluence map that corresponds to the patient.

公开(公告)号：US20240207646A1

公开(公告)日：2024-06-27

申请号：US18433361

申请日：2024-02-05

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Johannes STAHL ,  Jonathan MALTZ

IPC: A61N5/10

CPC classification number: A61N5/1045 ,  A61N5/1036 ,  A61N5/1049 ,  A61N5/1031 ,  A61N2005/1032 ,  A61N2005/1035 ,  A61N5/1039 ,  A61N2005/1041 ,  A61N5/1077

Abstract: A method for delivering radiation treatment may include defining a preliminary trajectory including a plurality of control points. Each control point may be associated with position parameters of a gantry and a couch. The method may also include generating a treatment plan based on the preliminary trajectory by optimizing an intensity and position parameters of a collimator and MLC leaves for each control point. The method may also include decomposing the treatment plan into a delivery trajectory including the plurality of control points. Each of the plurality of control points may be further associated with the optimized intensity, the optimized position parameters of the collimator and the MLC leaves, an output rate, and a motion parameter of each of the gantry, the couch, the collimator, and the MLC leaves. The method may further include instructing a radiation delivery device to deliver the treatment plan according to the delivery trajectory.

公开(公告)号：US11980775B2

公开(公告)日：2024-05-14

申请号：US17010184

申请日：2020-09-02

Applicant: Varian Medical Systems International AG

Inventor： Emmi Ruokokoski ,  Jarkko Y. Peltola ,  Esa Kuusela

IPC: A61N5/10 ,  G06F21/84 ,  G06F30/30

CPC classification number: A61N5/1031 ,  A61N5/1036 ,  A61N5/1038 ,  A61N5/1037 ,  A61N2005/1041 ,  G06F21/84 ,  G06F30/30

Abstract: Generally speaking, pursuant to these various embodiments a memory stores prescribed treatment instructions for a particular patient radiation therapy. Those treatment instructions specify clinical metrics for goals pertaining to at least one treatment volume for the particular patient. Either directly or inferentially those clinical metrics are prioritized. A control circuit automatically converts those treatment instructions into resultant radiation treatment plan optimization objectives where the automatic conversion can compatibly comprise a non-convex optimization objective. The control circuit then automatically iteratively optimizes the radiation treatment plan for the particular patient radiation therapy as a function, at least in part, of the aforementioned resultant optimization objectives to thereby produce an optimized radiation treatment plan for the particular patient that a radiation treatment platform then utilizes to administer therapeutic radiation to the particular patient.

公开(公告)号：US11759655B2

公开(公告)日：2023-09-19

申请号：US15794198

申请日：2017-10-26

Applicant: Varian Medical Systems International AG

Inventor： Janne I. Nord ,  Esa Kuusela ,  Jarkko Y. Peltola ,  Juha Kauppinen

IPC: A61N5/10 ,  G21K1/04

CPC classification number: A61N5/1045 ,  A61N5/1047 ,  G21K1/046 ,  A61N5/1036

Abstract: A multi-layer multi-leaf collimation system includes at least a two layers of collimation leaves. The first multi-leaf collimator layer is configured to primarily perform a first function to affect a radiation beam traveling from a radiation source to a target and a second multi-leaf collimator layer is configured to primarily perform a second function, different from the first function, to affect the radiation beam for the administration of a treatment plan.

公开(公告)号：US11691027B2

公开(公告)日：2023-07-04

申请号：US17170683

申请日：2021-02-08

Applicant: Siemens Healthineers International AG ,  The Board of Trustees of the Leland Stanford Junior University

Inventor： Christopher Barry Locke ,  Santtu Ollila ,  Karl Kenneth Bush

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1036 ,  A61N5/1047

Abstract: Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of planning target volumes (PTVs), a post-processing step may be performed to enlarge certain BEV regions, which are considered for exposing during treatment trajectory optimization.

公开(公告)号：US20180012676A1

公开(公告)日：2018-01-11

申请号：US15642091

申请日：2017-07-05

Applicant: Shenyang Neusoft Medical Systems Co., Ltd.

Inventor： Xinghu XU ,  Meng CHAI

IPC: G21K1/04

CPC classification number: G21K1/046 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1065

Abstract: Methods and devices for controlling movement of a carriage of a multi-leaf collimator are provided. In one aspect, a method includes obtaining a desired position of each of a set of leaves on the carriage in each of a plurality of segments from a field, determining an allowable moving range set of the carriage according to the desired position, the allowable moving range set including a respective allowable moving range of the carriage in each of the segments, determining a respective position of the carriage in each of the segments according to the allowable moving range set, and controlling the movement of the carriage according to the determined positions of the carriage in the segments.

公开(公告)号：US09764159B2

公开(公告)日：2017-09-19

申请号：US15266156

申请日：2016-09-15

Applicant: Varian Medical Systems International AG

Inventor： Karl Otto

IPC: A61N5/10 ,  A61B34/10

CPC classification number: A61B5/4836 ,  A61B5/08 ,  A61B5/113 ,  A61B34/10 ,  A61B2034/101 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1036 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1042 ,  A61N5/1045 ,  A61N5/1047 ,  A61N5/1049 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1082 ,  A61N2005/1032 ,  A61N2005/1034 ,  A61N2005/1035

Abstract: Methods for delivering radiation dose to a target area within a subject comprise: defining a trajectory comprising relative movement between a treatment radiation source and the subject and determining a radiation delivery plan; and, while effecting relative movement between the treatment radiation source and the subject along the trajectory, delivering a treatment radiation beam from the treatment radiation source to the subject according to the radiation delivery plan to impart a dose distribution on the subject. Delivering the treatment radiation beam from the treatment radiation source to the subject comprises varying an intensity of the treatment radiation beam over at least a portion of the trajectory. Varying the intensity of the treatment radiation beam comprises varying a radiation output rate of the treatment radiation source in accordance with the radiation delivery plan while effecting relative movement between the treatment radiation source and the subject along the trajectory.

公开(公告)号：US20170189716A1

公开(公告)日：2017-07-06

申请号：US15394829

申请日：2016-12-30

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Weiyuan WANG

IPC: A61N5/10

CPC classification number: A61N5/1036 ,  A61N5/1045

Abstract: The present disclosure provides a radiation method for radiating a fluence map having a zero-fluence region under a movement of MLC (Multi-Leaf Collimator) includes a determining step of determining at least one basic fluence map from the fluence map. The basic fluence map includes a first non-zero fluence region and a second non-fluence region having the zero-fluence region therebetween. The radiation method includes a first radiating step including radiating the first non-zero fluence region, along with moving a first group of leaf pairs and moving a vertical jaw to shade the first group of leaf pairs, and a second radiating step including radiating the second non-zero fluence region, along with moving a second group of leaf pairs and withdrawing the vertical jaw to expose the second group of leaf pairs.

公开(公告)号：US09687674B2

公开(公告)日：2017-06-27

申请号：US15266225

申请日：2016-09-15

Applicant: Varian Medical Systems International AG

Inventor： Karl Otto

IPC: A61N5/10 ,  A61B34/10

CPC classification number: A61B5/4836 ,  A61B5/08 ,  A61B5/113 ,  A61B34/10 ,  A61B2034/101 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1036 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1042 ,  A61N5/1045 ,  A61N5/1047 ,  A61N5/1049 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1082 ,  A61N2005/1032 ,  A61N2005/1034 ,  A61N2005/1035

Abstract: Systems for delivering radiation dose to a target area within a subject comprise: a radiation source for outputting a radiation beam; a support for supporting the subject; a movement mechanism for moving the radiation source relative to the subject along a trajectory; one or more sensors for monitoring a position of the subject; and a controller configured, in accordance with a radiation delivery plan, to: determine the position from one or more signals received from the one or more sensors; deactivate delivery of the treatment radiation beam upon determining that the position is outside of an acceptable range; and reactivate delivery of the treatment radiation beam upon determining that the position is within the acceptable range, to thereby deliver dose to the subject according to the radiation delivery plan.

公开(公告)号：US20170087387A1

公开(公告)日：2017-03-30

申请号：US14865890

申请日：2015-09-25

Applicant: Varian Medical Systems Inc. ,  Varian Medical Systems International AG

Inventor： Janne I. Nord ,  Jarkko Y. Peltola ,  Esa Kuusela ,  Steven W. Prince

IPC: A61N5/10

CPC classification number: A61N5/1045 ,  A61N5/1036 ,  A61N2005/1074 ,  A61N2005/1095 ,  G21K1/046

Abstract: A control circuit administers a radiation treatment plan that specifies a planned total radiation dose for a radiation treatment session for a given patient by modulating a radiation beam with at least one high-resolution aperture that is formed using one of a plurality of linearly-sequential high-resolution aperture possibilities. By one approach the foregoing comprises modulating the radiation beam using at least substantially only high-resolution apertures that are formed using a plurality of the linearly-sequential high-resolution aperture possibilities. In some cases the foregoing can comprise administering the radiation treatment plan using at least two separate radiation exposures for only a single treatment field, in which case, by one approach, each of the separate radiation exposures for the single treatment field can comprise modulating the radiation beam using at least substantially only high-resolution apertures.