-
公开(公告)号:US20080089864A1
公开(公告)日:2008-04-17
申请号:US11809191
申请日:2007-05-31
CPC分类号: C12N7/00 , A61K35/761 , A61K48/00 , C12N15/86 , C12N2710/10322 , C12N2710/10332 , C12N2710/10343 , C12N2710/10361 , C12N2710/10364
摘要: This invention refers to the use of an adenovirus for cancer treatment, being this adenovirus defective in its virus-associated (VA) RNAs. Said adenovirus has a mutation in the VAI or VAII gene sequence or both. This adenovirus may also have mutations in the sequences controlling expression of the VA RNAs.
摘要翻译: 本发明涉及用于癌症治疗的腺病毒,其病毒相关(VA)RNA中的该腺病毒是有缺陷的。 所述腺病毒在VAI或VAII基因序列中具有突变或两者。 该腺病毒也可能在控制VA RNA表达的序列中具有突变。
-
公开(公告)号:US20090202489A2
公开(公告)日:2009-08-13
申请号:US11809191
申请日:2007-05-31
申请人: Ramon Bonastre , Manel Piqueras
发明人: Ramon Bonastre , Manel Piqueras
CPC分类号: C12N7/00 , A61K35/761 , A61K48/00 , C12N15/86 , C12N2710/10322 , C12N2710/10332 , C12N2710/10343 , C12N2710/10361 , C12N2710/10364
摘要: This invention refers to the use of an adenovirus for cancer treatment, being this adenovirus defective in its virus-associated (VA) RNAs. Said adenovirus has a mutation in the VAI or VAII gene sequence or both. This adenovirus may also have mutations in the sequences controlling expression of the VA RNAs.
摘要翻译: 本发明涉及用于癌症治疗的腺病毒,其病毒相关(VA)RNA中的该腺病毒是有缺陷的。 所述腺病毒在VAI或VAII基因序列中具有突变或两者。 该腺病毒也可能在控制VA RNA表达的序列中具有突变。
-
3.
公开(公告)号:US20060233753A1
公开(公告)日:2006-10-19
申请号:US10509194
申请日:2003-03-25
申请人: Ramon Bonastre , Manel Piqueras
发明人: Ramon Bonastre , Manel Piqueras
IPC分类号: A61K48/00
CPC分类号: C12N7/00 , A61K35/761 , A61K48/00 , C12N15/86 , C12N2710/10322 , C12N2710/10332 , C12N2710/10343 , C12N2710/10361 , C12N2710/10364
摘要: This invention refers to the use of an adenovirus for cancer treatment, being this adenovirus defective in its virus-associated (VA) RNAs. Said adenovirus has a mutation in the VAI or VAII gene sequence or both. This adenovirus may also have mutations in the sequences controlling expression of the VA RNAs.
摘要翻译: 本发明涉及用于癌症治疗的腺病毒,其病毒相关(VA)RNA中的该腺病毒是有缺陷的。 所述腺病毒在VAI或VAII基因序列中具有突变或两者。 该腺病毒也可能在控制VA RNA表达的序列中具有突变。
-
-