公开(公告)号：US20220241611A1

公开(公告)日：2022-08-04

申请号：US17612666

申请日：2020-05-12

Applicant: RaySearch Laboratories AB

Inventor： Rasmus BOKRANTZ ,  Kjell ERIKSSON ,  Fredrik LÖFMAN

IPC: A61N5/10

Abstract: Better Pareto dose distributions for multi-criteria optimization of treatment plans can be obtained by obtaining at least one reference dose function designed to result in an acceptable reference dose distribution, defining a multi-criteria optimization problem including the at least one reference dose function as at least one optimization function, performing at least two optimization procedures based on the multi-criteria optimization problem to generate a set of at least two possible treatment plans, obtaining a treatment plan to be used for treating the patient, based on the set of possible treatment plans, by selecting one plan or by combining plans.

公开(公告)号：US20220072334A1

公开(公告)日：2022-03-10

申请号：US17415768

申请日：2019-12-12

Applicant: RaySearch Laboratories AB

Inventor： Albin FREDRIKSSON ,  Rasmus BOKRANTZ ,  Erik ENGWALL ,  Kjell ERIKSSON ,  Lars GLIMELIUS

IPC: A61N5/10 ,  G16H20/40 ,  G16H40/20

Abstract: A method of optimizing the use of resources in treatment planning involving more than one radiation set delivered to one or more patients, the radiation sets requiring different resources, respectively, wherein the optimization is performed using an optimization problem comprising an optimization function related to the first and second sets of resources. The method may be used for optimizing one plan for one patient, or a number of plans for different patients, in such a way that the available resources are used in the best possible way.

公开(公告)号：US20230211177A1

公开(公告)日：2023-07-06

申请号：US17996620

申请日：2021-04-09

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Martin JANSON ,  Albin FREDRIKSSON ,  Erik TRANEUS ,  Kjell ERIKSSON

IPC: A61N5/10 ,  G16H20/40

CPC classification number: A61N5/1031 ,  G16H20/40 ,  A61N2005/1087

Abstract: An inverse-planning method (100), by which a treatment plan specifying a non-photon irradiation of a patient including a target volume is generated, comprises: obtaining (110, 112) first and second plan goals in terms of a respective first and second numerical condition on the treatment plan’s photon-equivalent dose as computed using a first and second RBE factor; and generating (114) the treatment plan by an optimization process aiming to satisfy the first, second and any further plan goals, wherein (a) the first and second plan goals apply to volumes which either are included in the TV or are completely or partially separate from the TV and/or (b) the first and second RBE factors are variable. In a further aspect, a data carrier provides a treatment plan with these characteristics together with reporting quantities relating to fulfilment of the first and second plan goals.

公开(公告)号：US20210205635A1

公开(公告)日：2021-07-08

申请号：US17057170

申请日：2019-05-27

Applicant: RaySearch Laboratories AB

Inventor： Rasmus BOKRANTZ ,  Albin FREDRIKSSON ,  Kjell ERIKSSON ,  Erik ENGWALL ,  Erik TRANEUS

IPC: A61N5/10

Abstract: The present disclosure generally relates to the field of radiation treatment. More specifically, the present disclosure generally relates to methods and radiation treatment systems for facilitating a multimodal radiation therapy treatment plan, in particular a multimodal radiation therapy plan employing a combined photon beam and electron beam radiation treatment. According to one example embodiment described in the disclosure, a method may comprise obtaining information related to a set of candidate beam types for the combined photon beam and electron beam radiation treatment; comparing the set of candidate beam types against a selection criterion to establish a subset of beam types from the candidate beam types; and generating the combined photon beam and electron beam radiation treatment plan utilizing the thus established subset of beam types.

公开(公告)号：US20180221685A1

公开(公告)日：2018-08-09

申请号：US15580765

申请日：2016-06-09

Applicant: RaySearch Laboratories AB

Inventor： Kjell ERIKSSON

IPC: A61N5/10 ,  G16H50/20

CPC classification number: A61N5/1036 ,  G06F19/3481 ,  G16H50/20

Abstract: An interpolation of deliverable radiotherapy treatment plans is facilitated by restricting the movement of the multi-leaf collimator leaves between optimization steps.

公开(公告)号：US20230144962A1

公开(公告)日：2023-05-11

申请号：US17907546

申请日：2021-03-22

Applicant: RaySearch Laboratories AB (Pub)

Inventor： Bjorn ANDERSSON ,  Erik ENGWALL ,  Albin FREDRIKSSON ,  Kjell ERIKSSON

IPC: A61N5/10

CPC classification number: A61N5/1001 ,  A61N5/103 ,  A61N5/1038

Abstract: A computer-based method of optimizing a radiotherapy treatment plan for a patient is proposed, wherein a complete treatment comprising both external beam therapy and brachytherapy is optimized in one procedure using an optimization problem comprising an objective function designed to optimize the total dose distribution as a combination of a first dose distribution to be provided by a first radiation set and a second dose distribution to be provided by a second radiation set. One of the radiation sets is external beam radiotherapy and the other is brachytherapy. The optimization is based on a total desired dose for the whole treatment, images of the patient before the treatment starts and an estimated image of the patient after the first radiation set has been delivered.

公开(公告)号：US20230115222A1

公开(公告)日：2023-04-13

申请号：US17906453

申请日：2021-03-16

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Erik TRANEUS ,  Bjorn HARDEMARK ,  Kjell ERIKSSON

IPC: A61N5/10 ,  G16H20/40

Abstract: A radiotherapy treatment planning method for achieving a FLASH radiotherapy treatment plan involves optimizing the plan using an optimization problem that has been designed to maximize the part of the irradiation that will be delivered under FLASH conditions, in particular to an organ at risk, to minimize the damage to the organ at risk.

公开(公告)号：US20210220671A1

公开(公告)日：2021-07-22

申请号：US15733906

申请日：2019-06-25

Applicant: RaySearch Laboratories AB

Inventor： Kjell ERIKSSON

IPC: A61N5/10

Abstract: A method of radiotherapy treatment planning involves dynamic target tracking and beam redirection. A set of 3D images of a patient reflecting a movement of the patient is obtained, and each image is deformably registered with one reference image. The accumulated dose is calculated as the sum of the dose distribution over all phases in dependence of the patient movement and the model of the delivery machine, the dose distribution for each phase being deformed by means of the deformation map for the respective phase, to match the reference image.

公开(公告)号：US20240221899A1

公开(公告)日：2024-07-04

申请号：US18555004

申请日：2022-04-13

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Erik TRANEUS ,  Albin FREDRIKSSON ,  Kjell ERIKSSON ,  Jakob ODÉN

IPC: G16H20/40 ,  A61N5/10

CPC classification number: G16H20/40 ,  A61N5/1038

Abstract: A combined set of treatment plans including radiation treatment and hyperthermia treatment may be optimized either by co-optimizing both plans together or by optimizing one of the plans and then optimizing the other taking into account the predicted effect of the first optimized plan.

公开(公告)号：US20210213303A1

公开(公告)日：2021-07-15

申请号：US17058176

申请日：2019-06-10

Applicant: RaySearch Laboratories AB

Inventor： Rasmus BOKRANTZ ,  Kjell ERIKSSON ,  Tianfang ZHANG

IPC: A61N5/10

Abstract: A method of obtaining an interpolated treatment plan is based on interpolating between associated dose distributions through optimization with respect to an optimization problem comprising optimization functions based on deviations from clinical goals. The method may suitably be used to improve navigated plans resulting from multi-criteria optimization.