公开(公告)号：US20160209405A1

公开(公告)日：2016-07-21

申请号：US14676620

申请日：2015-04-01

Applicant: Regents of the University of Minnesota

Inventor： Jian-Ping Wang ,  Wei Wang ,  Yi Wang ,  Todd Klein

IPC: G01N33/543 ,  G01N33/53 ,  G01R33/09

CPC classification number: G01N33/54326 ,  G01N33/84 ,  G01R33/0094 ,  G01R33/09 ,  G01R33/093 ,  G01R33/1269

Abstract: A system may include a magnetic sensor including a free magnetic layer and a fixed magnetic layer; a sample container disposed over the magnetic stack; a plurality of capture DNA oligomers on a surface of the magnetic biosensor within the volume defined by the sample container above the magnetic stack, wherein each of the plurality of capture DNA oligomers includes at least one thymine base configured to bind to an Hg2+ ion; a magnetic field generator configured to generate a magnetic field that influences the free layer; and circuitry configured to measure a resistance of the magnetic sensor.

Abstract translation: 系统可以包括包括自由磁性层和固定磁性层的磁传感器; 设置在所述磁性堆叠上的样品容器; 所述磁性生物传感器的表面上的多个捕获DNA寡聚体在由所述磁性堆叠物上方的所述样品容器限定的体积内，其中所述多个捕获DNA寡聚体中的每一个包含至少一个被配置为结合Hg 2+离子的胸腺嘧啶碱基; 磁场发生器，被配置为产生影响自由层的磁场; 以及被配置为测量磁传感器的电阻的电路。