公开(公告)号：US20130102894A1

公开(公告)日：2013-04-25

申请号：US13642212

申请日：2011-04-16

申请人： Reginald Birngruber ,  Ralf Brinkmann ,  Gereon Huettmann ,  Heike Mueller

发明人： Reginald Birngruber ,  Ralf Brinkmann ,  Gereon Huettmann ,  Heike Mueller

IPC分类号： A61B5/00 ,  A61N5/00

CPC分类号： A61B5/0066 ,  A61B5/0097 ,  A61B5/015 ,  A61B5/05 ,  A61B5/7225 ,  A61B5/742 ,  A61B18/20 ,  A61B2018/00636 ,  A61F9/008 ,  A61N5/00

摘要： A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue, characterized by a computational unit for carrying out the following steps: determining the depth-resolved tissue velocity in the radiation direction of the measurement light at a predetermined measurement point of the tissue from the phase information from the FD-OCT interference light, integrating the established tissue velocity over time, differentiating the calculated time integral with respect to space, and displaying the spatial derivative as a function of space and time and/or feeding the spatial derivative as a function of space and time to an evaluation module and/or feeding the spatial derivative as a function of space and time to the control unit.

摘要翻译： 一种用于通过吸收电磁辐射的局部加热来检查或处理生物体组织的装置，具有至少一个发射电磁辐射的辐射源，用于控制辐射源的照射参数的控制单元和至少一个FD- OCT装置，具有发射用于照射组织区域的测量光的光源，其中电磁辐射被组织吸收，其特征在于用于执行以下步骤的计算单元：确定辐射方向上的深度分辨组织速度 根据来自FD-OCT干涉光的相位信息在组织的预定测量点处的测量光，将所建立的组织速度随时间积分，将所计算的时间积分与空间进行微分，并将空间导数作为 空间和时间和/或馈送空间导数作为功能 n到评估模块的空间和时间和/或将空间导数作为空间和时间的函数馈送到控制单元。

公开(公告)号：US08774904B2

公开(公告)日：2014-07-08

申请号：US13642212

申请日：2011-04-16

申请人： Reginald Birngruber ,  Ralf Brinkmann ,  Gereon Huettmann ,  Heike Mueller

发明人： Reginald Birngruber ,  Ralf Brinkmann ,  Gereon Huettmann ,  Heike Mueller

IPC分类号： A61B6/00

CPC分类号： A61B5/0066 ,  A61B5/0097 ,  A61B5/015 ,  A61B5/05 ,  A61B5/7225 ,  A61B5/742 ,  A61B18/20 ,  A61B2018/00636 ,  A61F9/008 ,  A61N5/00

摘要： A device for examining or treating living tissue by means of local heating of the tissue by absorbing electromagnetic radiation, with at least one radiation source emitting electromagnetic radiation, a control unit for controlling the irradiation parameters of the radiation source, and at least one FD-OCT apparatus with a light source emitting a measurement light for illuminating that tissue region in which the electromagnetic radiation is absorbed by the tissue, characterized by a computational unit for carrying out the following steps: determining the depth-resolved tissue velocity in the radiation direction of the measurement light at a predetermined measurement point of the tissue from the phase information from the FD-OCT interference light, integrating the established tissue velocity over time, differentiating the calculated time integral with respect to space, and displaying the spatial derivative as a function of space and time and/or feeding the spatial derivative as a function of space and time to an evaluation module and/or feeding the spatial derivative as a function of space and time to the control unit.

摘要翻译： 一种用于通过吸收电磁辐射的局部加热来检查或处理生物体组织的装置，具有至少一个发射电磁辐射的辐射源，用于控制辐射源的照射参数的控制单元和至少一个FD- OCT装置，具有发射用于照射组织区域的测量光的光源，其中电磁辐射被组织吸收，其特征在于用于执行以下步骤的计算单元：确定辐射方向上的深度分辨组织速度 根据来自FD-OCT干涉光的相位信息在组织的预定测量点处的测量光，将所建立的组织速度随时间积分，将所计算的时间积分与空间进行微分，并将空间导数作为 空间和时间和/或馈送空间导数作为功能 n到评估模块的空间和时间和/或将空间导数作为空间和时间的函数馈送到控制单元。

公开(公告)号：US20100292539A1

公开(公告)日：2010-11-18

申请号：US12780352

申请日：2010-05-14

申请人： Eva Lankenau ,  Tim Bonin ,  Gereon Huettmann

发明人： Eva Lankenau ,  Tim Bonin ,  Gereon Huettmann

IPC分类号： A61B1/07

CPC分类号： G01B9/0205 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02057 ,  G01B9/02091 ,  G01N21/4795

摘要： An apparatus for optical coherence tomography has a broadband light source with a short coherence length, an optical fiber that guides the light from the light source to a focusing optics, and a graded-index optics arranged between the optical fiber and the focusing optics with two opposite parallel flat sides, that is contacted on its first flat side by the optical fiber forming an irradiation point guiding light to the graded-index optics and having a pitch of N/8, N being a natural number that cannot be divided by 4. A first structure for light reflection is arranged on the first flat side of the graded-index optics adjacent to the irradiation point, and a second structure for beam splitting is arranged on the second flat side of the graded-index optics. The focusing optics are designed for focusing the light transmitted by the second structure essentially at right angles to the flat sides of the graded-index optics.

摘要翻译： 用于光学相干断层摄影的装置具有短的相干长度的宽带光源，将来自光源的光引导到聚焦光学器件的光纤，以及布置在光纤和聚焦光学器件之间的渐变折射率光学器件，其具有两个 相反的平行平面，通过光纤在其第一平面侧接触，形成照射点将光引导到渐变折射率光学器件，并具有N / 8的间距，N是不能被除以4的自然数。 用于光反射的第一结构布置在与照射点相邻的渐变折射率光学器件的第一平面侧，并且用于分束的第二结构布置在渐变折射率光学器件的第二平坦侧上。 聚焦光学设计用于将由第二结构传播的光基本上与渐变折射率光学器件的平坦侧面成直角聚焦。

公开(公告)号：US07961333B2

公开(公告)日：2011-06-14

申请号：US12307808

申请日：2007-07-04

申请人： Gereon Huettmann ,  Peter Koch

发明人： Gereon Huettmann ,  Peter Koch

IPC分类号： G01B9/02 ,  G01B11/02

CPC分类号： G01J9/02 ,  G01N21/4795

摘要： A method is provided for the electronic scanning of the intensity distribution of an optical interference pattern by means of a linear image sensor, wherein the interference pattern is produced by overlapping two temporally partly coherent beams striking at an arbitrarily predefined angle α in relation to one another and is provided with an interference strip having a carrier frequency greater than the scanning frequency, and amplitude modulation that can be varied slowly in relation to the pixel width, wherein at least one optical grating is disposed in the beam path of at least one of two incident beams and the image sensor is disposed in the diffraction image of the grating(s) such that, at the site of the image sensor, the beams interfere, and the beams enclose an angle β at the site of the image sensor, the angle being smaller than α.

摘要翻译： 提供了一种通过线性图像传感器对光学干涉图案的强度分布进行电子扫描的方法，其中通过将两个相对于彼此以任意预定角度α的两个时间上部分相干的光束重叠而产生干涉图案 并且设置有具有大于扫描频率的载波频率的干涉条，以及可以相对于像素宽度缓慢变化的幅度调制，其中至少一个光栅设置在两个的至少一个的光束路径中 入射光束和图像传感器设置在光栅的衍射图像中，使得在图像传感器的位置处，光束干涉，并且光束包围角度＆bgr; 在图像传感器的位置处，角度小于α。

公开(公告)号：US07484665B2

公开(公告)日：2009-02-03

申请号：US10551308

申请日：2004-03-13

申请人： Peter Koch ,  Gereon Huettmann ,  Edmund Koch ,  Eva Lankenau

发明人： Peter Koch ,  Gereon Huettmann ,  Edmund Koch ,  Eva Lankenau

IPC分类号： G06K7/10

CPC分类号： G06K7/10712 ,  G06K19/06046 ,  G06K2019/06234

摘要： This invention relates to a method for reading, while using optical interference, a barcode that extends into the depth of a substrate. The barcode is represented by an area with marks in the substrate that is partially transparent to electromagnetic radiation. The inventive method comprises the steps of irradiating the substrate with short coherence length light from a broad-band light source, dividing the light up into reference light and measuring light, returning the reference light and the measuring light back-scattered or reflected in the marked area to an analytical unit, determining the reflectance or the reflectivity of the substrate for all layer depths in the marked area from the interference of the reference light and the measuring light and interpreting the result as a barcode.

摘要翻译： 本发明涉及一种在使用光学干涉的情况下读取延伸到基板深度的条形码的方法。 条形码由在基板中具有对电磁辐射部分透明的标记的区域表示。 本发明的方法包括以下步骤：从宽带光源照射具有短相干长度光的基板，将光分成参考光和测量光，返回参考光和被散射或反射在标记的光 区域到分析单元，从参考光和测量光的干涉中确定标记区域中所有层深度的衬底的反射率或反射率，并将结果解释为条形码。

公开(公告)号：US20100020328A1

公开(公告)日：2010-01-28

申请号：US12307808

申请日：2007-07-04

申请人： Gereon Huettmann ,  Peter Koch

发明人： Gereon Huettmann ,  Peter Koch

IPC分类号： G01B9/02

CPC分类号： G01J9/02 ,  G01N21/4795

摘要： A method is provided for the electronic scanning of the intensity distribution of an optical interference pattern by means of a linear image sensor, wherein the interference pattern is produced by overlapping two temporally partly coherent beams striking at an arbitrarily predefined angle α in relation to one another and is provided with an interference strip having a carrier frequency greater than the scanning frequency, and amplitude modulation that can be varied slowly in relation to the pixel width, wherein at least one optical grating is disposed in the beam path of at least one of two incident beams and the image sensor is disposed in the diffraction image of the grating(s) such that, at the site of the image sensor, the beams interfere, and the beams enclose an angle β at the site of the image sensor, the angle being smaller than α.

摘要翻译： 提供了一种通过线性图像传感器对光学干涉图案的强度分布进行电子扫描的方法，其中通过将两个相对于彼此以任意预定义的角度α相撞的两个时间上部分相干的光束重叠而产生干涉图案 并且设置有具有大于扫描频率的载波频率的干涉条，以及可以相对于像素宽度缓慢变化的幅度调制，其中至少一个光栅设置在两个的至少一个的光束路径中 入射光束和图像传感器设置在光栅的衍射图像中，使得在图像传感器的位置处，光束干涉，并且光束在图像传感器的位置处包围角度β，角度 小于α。