PROCESS FOR PREPARING 2,2-DIFLUOROETHYLAMINE FROM 2,2-DIFLUORO-1-CHLOROETHANE AND AMMONIA
    10.
    发明申请
    PROCESS FOR PREPARING 2,2-DIFLUOROETHYLAMINE FROM 2,2-DIFLUORO-1-CHLOROETHANE AND AMMONIA 有权
    从2,2-二氟-1-氯代乙酸和氨基磺酸制备2,2-二氟乙酰胺的方法

    公开(公告)号:US20120184777A1

    公开(公告)日:2012-07-19

    申请号:US13348484

    申请日:2012-01-11

    IPC分类号: C07C209/08

    摘要: Process for preparing 2,2-difluoroethylamine, comprising the following steps: (i) mixing 2,2-difluoro-1-chloroethane and gaseous, liquid or supercritical ammonia in a pressure-stable, closed reaction vessel under a pressure in the range from 10 to 180 bar; (ii) reacting the reaction mixture at a reaction temperature in the range from 80° C. to 200° C.; (iii) letting down the reaction mixture and isolating 2,2-difluoroethylamine.

    摘要翻译: 制备2,2-二氟乙胺的方法,包括以下步骤:(i)将2,2-二氟-1-氯乙烷与气态,液态或超临界氨在压力稳定的封闭反应容器中混合,压力范围为 10至180巴; (ii)使反应混合物在80℃至200℃的反应温度下反应; (iii)放下反应混合物并分离出2,2-二氟乙胺。