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1.
公开(公告)号:US08653260B2
公开(公告)日:2014-02-18
申请号:US13527934
申请日:2012-06-20
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Ding-Ming Shen , Liping Wang , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Ding-Ming Shen , Liping Wang , Cheng Zhu
IPC分类号: C07D253/08 , C07D487/04 , C07D495/04 , C07D239/80 , C07D241/12 , C07D265/06 , C07D237/14 , C07D237/16 , C07D237/32 , A61P13/06
CPC分类号: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)的化合物,其药物组合物及其用于治疗或预防由β3肾上腺素受体激活介导的疾病的方法。
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2.HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS 有权
标题翻译: 羟丙基吡咯烷酮作为3型ADRENERGIC受体激动剂公开(公告)号:US20090253705A1
公开(公告)日:2009-10-08
申请号:US12417239
申请日:2009-04-02
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
IPC分类号: A61K31/506 , C07D417/12 , C07D403/12 , C07D495/04 , C07D401/12 , A61K31/427 , A61K31/428 , A61K31/517 , A61K31/501 , A61K31/502 , A61K31/4439 , A61K31/41 , A61K31/437 , A61P13/10
CPC分类号: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)的化合物,其药物组合物及其用于治疗或预防由β3肾上腺素受体激活介导的疾病的方法。
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公开(公告)号:US08247415B2
公开(公告)日:2012-08-21
申请号:US12417239
申请日:2009-04-02
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
IPC分类号: C07D237/30 , C07D239/90 , C07D221/02 , C07D277/60 , A61K31/502 , A61K31/517 , A61K31/435 , A61K31/428 , A61P13/10 , A61P13/06
CPC分类号: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)化合物,其药物组合物及其用于治疗或预防由β-肾上腺素能受体激活介导的疾病的方法。
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4.
公开(公告)号:US08399480B2
公开(公告)日:2013-03-19
申请号:US12936221
申请日:2009-04-02
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
IPC分类号: A61K43/90 , A01K31/44 , C07D237/00
CPC分类号: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)化合物,其药物组合物及其用于治疗或预防由β-肾上腺素能受体激活介导的疾病的方法。
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5.HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS 有权
标题翻译: 羟丙基吡咯烷酮作为3型ADRENERGIC受体激动剂公开(公告)号:US20120258963A1
公开(公告)日:2012-10-11
申请号:US13527934
申请日:2012-06-20
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
IPC分类号: A61K31/41 , C07D403/12 , C07D413/12 , A61K31/427 , A61K31/428 , A61P13/00 , A61K31/416 , A61K31/4178 , A61K31/502 , A61K31/53 , A61K31/5355 , A61P13/10 , C07D417/12 , A61K31/4192
CPC分类号: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)化合物,其药物组合物及其用于治疗或预防由β-肾上腺素能受体激活介导的疾病的方法。
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6.HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS 有权
标题翻译: 羟丙基吡咯烷酮作为3型ADRENERGIC受体激动剂公开(公告)号:US20110028481A1
公开(公告)日:2011-02-03
申请号:US12936221
申请日:2009-04-02
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Sookhee Nicole Ha , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Cheng Zhu
IPC分类号: A61K31/427 , C07D417/12 , C07D403/12 , A61K31/428 , A61K31/502 , A61P13/10
CPC分类号: C07D487/04 , C07D401/12 , C07D403/12 , C07D417/12 , C07D471/04
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)化合物,其药物组合物及其用于治疗或预防由β-肾上腺素能受体激活介导的疾病的方法。
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7.HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS 有权
标题翻译: 羟丙基吡咯烷酮作为3型ADRENERGIC受体激动剂公开(公告)号:US20110028461A1
公开(公告)日:2011-02-03
申请号:US12936275
申请日:2009-03-23
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Bart Harper , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Harvey Wendt , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Bart Harper , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Harvey Wendt , Cheng Zhu
IPC分类号: A61K31/4439 , C07D417/14 , A61K31/502 , C07D413/14 , A61K31/5355 , A61P13/00 , A61P13/10
CPC分类号: C07D417/14 , C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D487/04 , C07D495/04
摘要: The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式I化合物,其药物组合物及其用于治疗或预防由β-肾上腺素能受体激活介导的疾病的方法。
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8.
公开(公告)号:US08501786B2
公开(公告)日:2013-08-06
申请号:US12936275
申请日:2009-03-23
申请人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Bart Harper , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Harvey Wendt , Cheng Zhu
发明人: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Bart Harper , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Harvey Wendt , Cheng Zhu
IPC分类号: A61K31/443 , A61K31/4436 , A61K31/4439 , C07D401/14 , C07D413/14 , C07D417/14
CPC分类号: C07D417/14 , C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14 , C07D487/04 , C07D495/04
摘要: The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式I化合物,其药物组合物及其用于治疗或预防由β3肾上腺素受体激活介导的疾病的方法。
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