公开(公告)号：US5090040A

公开(公告)日：1992-02-18

申请号：US321996

申请日：1989-03-10

申请人： Richard C. Lanza ,  Joseph R. Votano ,  Tomas Russ

发明人： Richard C. Lanza ,  Joseph R. Votano ,  Tomas Russ

IPC分类号： A61B6/00 ,  G01T1/29 ,  G06T1/60

CPC分类号： A61B6/505 ,  G01T1/2928 ,  G01T1/2935 ,  G06T1/60 ,  Y10S378/901

摘要： A data acquisition system is disclosed for use in radiographic imaging. The acquisition system includes at least two memory banks for storing radiographic data from a radiation detector, acquisition circuitry for sensing radiographic data when transmitted by the detector and for writing such data into one of the memory banks, and a controller for selecting a memory bank for storage of the data, and for switching from one memory bank to another, as well as for reading data from one or the other memory banks when such memory bank is not actively acquiring data.

摘要翻译： 公开了用于放射照相成像的数据采集系统。 采集系统包括至少两个用于存储来自辐射检测器的放射线照相数据的存储器组，用于当由检测器发送时用于感测放射线照相数据并用于将这样的数据写入存储体之一的采集电路，以及用于选择存储体的控制器 存储数据，以及从一个存储体切换到另一个存储体，以及当这种存储体未主动获取数据时从一个或另一个存储体读取数据。

公开(公告)号：US4956859A

公开(公告)日：1990-09-11

申请号：US321989

申请日：1989-03-10

申请人： Richard C. Lanza ,  Joseph R. Votano

发明人： Richard C. Lanza ,  Joseph R. Votano

IPC分类号： A61B6/00 ,  A61B6/04 ,  G21K1/10

CPC分类号： A61B6/505 ,  A61B6/00 ,  A61B6/0421 ,  G21K1/10

摘要： A system for analyzing biological structures by photon absorptiometry is disclosed, including a radiation source emitting photons and at least one source filter which operates to reduce the emission of high energy photons, thereby creating a sharp drop-off at the high end of the detected energy spectrum. The filter radiation is received by a detector which determines the spatial intensity of the radiation over the image area and preferably has a characteristics response which is relatively insensitive to low energy photons, such that the source filter and detector cooperate to measure the intensity of photons within a narrowed band of energy levels.

摘要翻译： 公开了一种用于通过光子吸收测量法分析生物结构的系统，包括发射光子的辐射源和至少一个源滤波器，其用于减少高能量光子的发射，由此在检测能量的高端产生急剧下降 光谱。 滤波器辐射由检测器接收，该检测器确定图像区域上的辐射的空间强度，并且优选地具有对低能光子相对不敏感的特性响应，使得源滤波器和检测器协调测量其内的光子的强度 缩小的能量带。

公开(公告)号：US5005195A

公开(公告)日：1991-04-02

申请号：US321766

申请日：1989-03-10

申请人： Richard C. Lanza ,  Joseph R. Votano

发明人： Richard C. Lanza ,  Joseph R. Votano

IPC分类号： A61B6/00 ,  G01T1/17 ,  G01T1/29

CPC分类号： A61B6/505 ,  G01T1/17 ,  G01T1/2935

摘要： A readout system is disclosed for use in conjunction with a radiation detector to obtain radiographic images. The readout system includes an event gating mechanism for receiving signals which are simultaneously generated at a plurality of locations within a radiation detector in response to a radiation event and an estimating mechanism for identifying the locus of the radiation event from the signals. In one illustrated embodiment the event gating mechanism further includes circuitry for receiving signals from a first and second set of lines defining a 2-dimensional coordinate grid within an area radiation detector.

摘要翻译： 公开了一种与放射线检测器一起使用以获得放射照相图像的读出系统。 读出系统包括事件门控机构，用于接收响应于辐射事件在辐射检测器内的多个位置处同时产生的信号，以及用于从信号中识别辐射事件轨迹的估计机构。 在一个示出的实施例中，事件门控机构还包括用于从定义区域辐射检测器内的二维坐标网格的第一组线路和第二组线路接收信号的电路。

公开(公告)号：US4973846A

公开(公告)日：1990-11-27

申请号：US322085

申请日：1989-03-10

申请人： Richard C. Lanza ,  Joseph R. Votano

发明人： Richard C. Lanza ,  Joseph R. Votano

IPC分类号： G01T1/185

CPC分类号： G01T1/185

摘要： Radiation detection methods and apparatus measure ionizing radiation propagating from a radiation source, utilizing a chamber having an electrically conductive sheet, an electrode assembly spaced apart from the conductive sheet and segmented into a plurality of electrically discrete electrode segments, and an ionizable medium disposed between the electrode assembly and conductive sheet, for absorbing the ionizing radiation and generating charged particles in proportion to the radiation energy absorbed. An electrical potential can be provided between the electrode assembly and conductive sheet, so that respective electrode segments collect the charged particles. Elements are provided for comparing the number of charged particles collected on respective electrode segments, to provide a measure of the energy distribution of the ionizing radiation, and for compensating for changes in capacitance or electrical potential between the electrode segments and the electrically conductive sheet elements.

摘要翻译： 辐射检测方法和装置测量从辐射源传播的电离辐射，利用具有导电片的腔室，与导电片隔开并分割成多个电离散的电极片段的电极组件，以及布置在 电极组件和导电片，用于吸收电离辐射并与吸收的辐射能量成比例地产生带电粒子。 可以在电极组件和导电片之间提供电位，使得各个电极段收集带电粒子。 提供元件用于比较在各个电极段上收集的带电粒子的数量，以提供电离辐射的能量分布的度量，以及补偿电极段和导电片元件之间的电容或电位的变化。

公开(公告)号：US5138553A

公开(公告)日：1992-08-11

申请号：US321764

申请日：1989-03-10

申请人： Richard C. Lanza ,  Joseph R. Votano

发明人： Richard C. Lanza ,  Joseph R. Votano

IPC分类号： A61B6/00 ,  G06F19/00

CPC分类号： A61B6/505

摘要： Methods and apparatus for precise and consistent selection of bone mineral content (BMC) measurement regions of selected bones, and accurate calculation of BMC from a displayed radiological image of the bones, calculate the position of the styloid tip of each bone, define a measurement region having selected positional correspondence to the position of the styloid tip, and sum pixel intensity values in the measurement region to yield a pixel intensity sum representative of bone mineral content. Bone density values are obtained by dividing the pixel intensity sum by a value representative of the areas of the measurement region, to yield a value representative of bone density. The position of the styloid tip is calculated by detecting selected transverse image edges, searching along the selected transverse image edges to determine a set of pixels which define extremities of the styloid tip, and defining a line substantially tangent to the styloid tip.

摘要翻译： 选择骨骼的骨矿物质含量（BMC）测量区域精确一致选择的方法和装置，从骨骼的显示放射学图像中精确计算BMC，计算每只骨骼的茎尖位置，定义一个测量区域 选择与茎突尖的位置的位置对应关系，并且在测量区域中求和像素强度值，以产生代表骨矿物质含量的像素强度之和。 通过将像素强度和除以表示测量区域的面积的值来获得骨密度值，以产生代表骨密度的值。 通过检测所选择的横向图像边缘，沿着所选择的横向图像边缘搜索来确定限定茎突末端的末端并且限定与茎突末端基本相切的线的像素集合来计算茎突尖的位置。

公开(公告)号：US5005196A

公开(公告)日：1991-04-02

申请号：US321990

申请日：1989-03-10

申请人： Richard C. Lanza ,  Joseph R. Votano

发明人： Richard C. Lanza ,  Joseph R. Votano

IPC分类号： A61B6/00 ,  H05G1/26 ,  H05G1/60

CPC分类号： A61B6/505 ,  H05G1/26 ,  H05G1/60

摘要： Devices and apparatus for limb positioning and instrument calibration are disclosed for use in radiographic imaging systems. In one aspect of the invention, a limb positioning device is disclosed, including a support surface for placement of a limb (e.g., typically a wrist) thereon, a pair of side blocks, at least one of which is moveable to accommodate placement of the limb therebetween, a biasing mechanism for urging the blocks together, and a clamping mechanism for immobilizing the limb between the side blocks and upon the support surface. In another aspect of the invention, a calibration apparatus is disclosed, including a positioning means for positioning a limb between a radiation source and a detector, and at least two blocks of material having different radiation absorptive properties, each block being disposed adjacent to the limb and also between the radiation source and the detector, such that differences in the intensity of radiation transmitted through materials can be sensed in the detector and used to calibrate the images of the limb during operation. In one embodiment, the two dissimilar materials further include a bone equivalent material and a tissue equivalent material.

摘要翻译： 用于肢体定位和仪器校准的装置和装置被公开用于放射成像系统。 在本发明的一个方面，公开了一种肢体定位装置，其包括用于在其上放置肢体（例如，通常是手腕）的支撑表面，一对侧块，其中至少一个侧块可移动以适应 其间具有用于将块推压在一起的偏压机构，以及用于将肢体固定在侧块之间和支撑表面上的夹持机构。 在本发明的另一方面，公开了一种校准装置，其包括用于在辐射源和检测器之间定位肢体的定位装置和具有不同辐射吸收特性的至少两个材料块，每个块邻近肢体设置 并且还在辐射源和检测器之间，使得可以在检测器中感测透射材料的辐射强度的差异，并用于在操作期间校准肢体的图像。 在一个实施方案中，两种不同的材料还包括骨当量材料和组织等效材料。

公开(公告)号：US06693281B2

公开(公告)日：2004-02-17

申请号：US10039487

申请日：2001-12-31

申请人： Gongyin Chen ,  Richard C. Lanza

发明人： Gongyin Chen ,  Richard C. Lanza

IPC分类号： G01N2300

CPC分类号： G01T1/2928

摘要： Methods and apparatus involving neutron resonance radiography are used to map the elemental composition of an object. Sets of neutrons having energies within particular energy bands are directed through an object to be imaged. The attenuation of the neutrons passed through the object is detected, and that data can be used to detect explosives, weapons, drugs and other contraband.

摘要翻译： 使用涉及中子共振射线照相术的方法和装置来绘制物体的元素组成。 在特定能带内具有能量的中子集被引导通过待成像的物体。 检测到通过物体的中子的衰减，该数据可用于检测炸药，武器，毒品等违禁品。

公开(公告)号：US06205195B1

公开(公告)日：2001-03-20

申请号：US09258483

申请日：1999-02-26

申请人： Richard C. Lanza

发明人： Richard C. Lanza

IPC分类号： G21G106

CPC分类号： G01V5/0069 ,  G01N23/204 ,  G01N23/22 ,  G01T1/295

摘要： This invention provides coded aperture imaging apparatus and methods for the detection and imaging of radiation which results from nuclear interrogation of a target object. The apparatus includes: 1) a radiation detector for detecting at least a portion of the radiation emitted by the object in response to nuclear excitation and for producing detection signals responsive to the radiation; 2) a coded aperture disposed between the detector and the object such that emitted radiation is detected by the detector after passage through the coded aperture; and 3) a data processor for characterizing the object based upon the detection signals from the detector and upon the configuration of the coded aperture. The method includes the steps of: 1) disposing a coded aperture in selected proximity to the object; 2) bombarding the object with a interrogation beam from a source of excitation energy; 3) detecting, with a detector, at least a portion of the radiation emitted in response to the interrogation beam, the detector producing detection signals responsive to the radiation, the detector being disposed so that the coded aperture is between the detector and the object and such that emitted radiation is detected by the detector after passage through the coded aperture; and 4) processing the detection signals to characterize the object based upon radiation detected by the detector after passage through the coded aperture, and based upon the configuration of the coded aperture.

摘要翻译： 本发明提供了编码孔径成像装置和用于由目标对象的核询问产生的辐射的检测和成像的方法。 该装置包括：1）辐射检测器，用于响应核激发检测物体发射的辐射的至少一部分，并产生响应于辐射的检测信号; 2）设置在检测器和物体之间的编码孔径，使得在通过编码孔径之后检测器发射的辐射被检测; 以及3）数据处理器，用于基于来自检测器的检测信号和编码孔径的配置来表征物体。 该方法包括以下步骤：1）将选定的编码孔径布置在物体附近; 2）用来自激发能源的询问光束轰击物体; 3）利用检测器检测响应于询问光束发射的辐射的至少一部分，检测器产生响应于辐射的检测信号，检测器被布置成使得编码孔径在检测器和物体之间，并且 使得发射的辐射在通过编码孔径之后由检测器检测; 以及4）根据经过编码孔径的检测器检测到的辐射，并且基于编码孔径的配置，处理检测信号以表征物体。

公开(公告)号：US4135091A

公开(公告)日：1979-01-16

申请号：US808515

申请日：1977-06-20

申请人： Richard C. Lanza ,  A. Robert Sohval

发明人： Richard C. Lanza ,  A. Robert Sohval

IPC分类号： G01T1/16 ,  G01T1/29 ,  G01T1/00

CPC分类号： G01T1/1606 ,  G01T1/2921 ,  Y10S505/848

摘要： A radiation imaging system employs a superheated, superconducting colloid detector subjected to an external magnetic field so that the colloid grains are maintained in a metastable superconducting state in the absence of radiation. Intersecting sets of select wires are imbedded in the detector that divide the detector into volumetric resolution elements. Grains in each resolution element that absorb photons emanating from an object "flip" to the normal conducting state. By applying coincident currents to the select wires defining each element, a local magnetic field is produced that opposes the external field so that all the "flipped" grains are reset to the superconducting state. This produces a flux change proportional to the number of photons incident on that element which is sensed and used to develop an x-ray image of the object.

摘要翻译： 放射线成像系统采用经过外部磁场的过热超导胶体检测器，使得胶体粒子在不存在辐射的情况下保持在亚稳态超导状态。 选择线的相交集合嵌入检测器中，将检测器分成体积分辨率元素。 每个分辨率元素中的粒子吸收从对象发出的光子“翻转”到正常导通状态。 通过对限定每个元件的选择线施加一致的电流，产生与外部场相对的局部磁场，使得所有的“翻转”晶粒被复位到超导状态。 这产生与入射到该元件上的光子数量成比例的磁通量变化，该光子被感测并用于显影物体的X射线图像。

公开(公告)号：US20080240535A1

公开(公告)日：2008-10-02

申请号：US12132500

申请日：2008-06-03

申请人： John V. Frangioni ,  Roberto Accorsi ,  Richard C. Lanza ,  John Idoine

发明人： John V. Frangioni ,  Roberto Accorsi ,  Richard C. Lanza ,  John Idoine

IPC分类号： G06K9/00

CPC分类号： A61B5/0059 ,  A61B5/415 ,  A61B5/418 ,  A61B6/00 ,  A61B6/037 ,  A61B6/4417 ,  A61B6/5247 ,  G01T1/1603 ,  G01T1/295 ,  G06F19/00

摘要： The invention relates to imaging systems that include a coded aperture detection system and an optical detection system. The coded aperture detection system is configured to detect radiation emitted by a radionuclide present within an object and to provide a first detector signal from the detected radiation. The optical detection system is configured to detect optical radiation from the object and to provide a second detector signal from the detected optical radiation. The system also includes a processor configured to prepare first image data from the first detector signal, second image data from the second detector signal, and registered data indicative of a spatial relationship in at least one dimension between the first and second image data. The invention also includes methods of using the new systems, e.g., for sentinel lymph node mapping and tissue resection.

摘要翻译： 本发明涉及包括编码孔径检测系统和光学检测系统的成像系统。 编码孔径检测系统被配置为检测存在于物体内的放射性核素发射的辐射并且从所检测的辐射提供第一检测器信号。 光学检测系统被配置为检测来自物体的光辐射并且从检测到的光辐射提供第二检测器信号。 该系统还包括配置成从第一检测器信号准备第一图像数据，来自第二检测器信号的第二图像数据和指示第一和第二图像数据之间的至少一维中的空间关系的登记数据的处理器。 本发明还包括使用新系统的方法，例如用于前哨淋巴结作图和组织切除术。