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公开(公告)号：US20060002887A1
公开(公告)日：2006-01-05
申请号：US11131944
申请日：2005-05-18
IPC分类号： A61K31/765
CPC分类号： A61K31/765 , A01N43/40 , A01N47/44 , A01N57/22 , A61K31/785 , C08G61/12 , C08G73/00 , C08G73/02 , C08G73/0226 , C08G73/0627 , Y02A50/473 , Y02A50/481
摘要： Polymerized ionene compounds are known to be effective antimicrobial substances. It has recently been appreciated that the molecular weight can affect the safety and efficacy of ionene compounds. In particular, it has been found that low molecular weight ionene oligomers (less than 50 repeat units) are less toxic than larger polymers with identical compositions. The invention discloses a plurality of ionene oligomers.
摘要翻译： 已知聚合的紫罗烯化合物是有效的抗微生物物质。 最近已经意识到分子量可以影响紫罗烯化合物的安全性和有效性。 特别地，已经发现低分子量的紫罗烯低聚物（小于50个重复单元）的毒性大于具有相同组成的较大的聚合物。 本发明公开了多种紫罗烯低聚物。
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2.发明申请公开(公告)号：US20060002888A1
公开(公告)日：2006-01-05
申请号：US11132150
申请日：2005-05-18
IPC分类号： A61K31/785
CPC分类号： A61K31/787 , A61K31/785 , A61K31/80 , Y02A50/473
摘要： A method of using ionene polymers for the treatment or prevention of infections (e.g., pulmonary infections) in cystic fibrosis patients is provided. The method comprises administering to a mammal an effective amount of an ionene polymer to prophylactically or therapeutically treat infections associated with cystic fibrosis.
摘要翻译： 提供了一种使用紫罗烯聚合物治疗或预防囊性纤维化患者感染（如肺部感染）的方法。 该方法包括向哺乳动物施用有效量的紫罗烯聚合物以预防或治疗地治疗与囊性纤维化相关的感染。
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公开(公告)号：US20070025954A1
公开(公告)日：2007-02-01
申请号：US11454142
申请日：2006-06-15
IPC分类号： A61K31/785 , C08G73/02
CPC分类号： C08G73/0627 , A61K31/74 , A61K31/785 , A61K31/787 , A61K31/80 , C08G61/12 , C08G73/00 , C08G73/0226
摘要： Disclosed are ionene polymers having antimicrobial activity. “Ionene polymers” as used in this invention are cationic polymers in which a substantial proportion of the atoms providing the positive charge are quaternized nitrogens located in the main polymeric chain or backbone of the polymer rather than in pendant groups. Also disclosed are antimicrobial compositions comprising ionene polymers and methods for treating microbial infections in mammals comprising the step of administering to a mammal, a therapeutically effective amount of at least one antimicrobial composition of the invention. Also disclosed are antimicrobial compositions comprising at least one ionene polymer and methods for preventing, inhibiting or eliminating the growth, dissemination, and/or the accumulation of microorganisms on a susceptible surface (including, but not limited to, the formation of biofilms on a susceptible surface) comprising the step of contacting such surface with a composition of the invention.
摘要翻译： 公开了具有抗微生物活性的紫罗烯聚合物。 本发明中使用的“紫罗烯聚合物”是阳离子聚合物，其中提供正电荷的大部分原子是位于聚合物的主要聚合物链或骨架中而不是侧基的季铵化氮。 还公开了包含紫罗烯聚合物和用于治疗哺乳动物微生物感染的方法的抗微生物组合物，其包括向哺乳动物施用治疗有效量的本发明的至少一种抗微生物组合物的步骤。 还公开了包含至少一种紫罗烯聚合物的抗微生物组合物和用于预防，抑制或消除微生物在易感表面上的生长，扩散和/或积累的方法（包括但不限于在易感的表面上形成生物膜 包括使这种表面与本发明的组合物接触的步骤。
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公开(公告)号：USD679580S1
公开(公告)日：2013-04-09
申请号：US29400399
申请日：2011-08-26
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公开(公告)号：US20120180359A1
公开(公告)日：2012-07-19
申请号：US13008747
申请日：2011-01-18
IPC分类号： F41C23/16
CPC分类号： F41C23/16
摘要： A hand guard for a firearm, the firearm being of a type comprising a barrel with a proximal hand guard retainer at a proximal end and a hand guard cap at a distal end. The hand guard cap comprises an end wall having an orifice configured to axially receive the barrel, and a proximally extending flange defining a select shape surrounding the orifice. The hand guard comprises at least first and second body pieces configured to mate lengthwise about a barrel of a firearm between a proximal hand guard retainer and a hand guard cap to form the hand guard. The body pieces cooperatively form a proximal hand guard retainer interface at a proximal end of the hand guard a hand guard cap interface at a distal end. The hand guard cap interface is configured to engage a first select shape defined by a proximally extending flange of a first hand guard cap and a second select shape defined by a proximally extending flange of a second hand guard cap.
摘要翻译： 枪支的护手，枪支是一种类型的枪械，枪管具有近端的近侧护手保持架和远端的护手帽。 护手帽包括具有构造成轴向容纳筒的孔的端壁和限定围绕孔的选择形状的近侧延伸的凸缘。 手护罩包括至少第一和第二主体构件，其构造成在近侧护手保持器和手护罩之间围绕枪支的纵向配合以形成护手。 身体部件协作地在护手的近端处形成近端护手保持器接口，其在远端处是护手帽接口。 护手帽接口构造成接合由第一手护罩的近侧延伸的凸缘限定的第一选择形状和由第二手护罩的近侧延伸的凸缘限定的第二选择形状。
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公开(公告)号：USD660200S1
公开(公告)日：2012-05-22
申请号：US29378511
申请日：2010-11-05
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公开(公告)号：US20110107643A1
公开(公告)日：2011-05-12
申请号：US12614051
申请日：2009-11-06
申请人： Richard Fitzpatrick , Michael T. Mayberry , Travis Darran Haley , Eric Christopher Burt , Brian Abbott , Mike Morgan
发明人： Richard Fitzpatrick , Michael T. Mayberry , Travis Darran Haley , Eric Christopher Burt , Brian Abbott , Mike Morgan
IPC分类号： F41C23/16
CPC分类号： F41C23/16
摘要： The firearm fore grip for use with a firearm having a barrel extending along a bore axis and an attachment rail operatively associated with the barrel and extending along the bore axis. The firearm fore grip comprises a base configured to engage an attachment rail, the base having a leading and a trailing end. A first hand contact surface is configured to extend substantially parallel to the attachment rail from the leading end of the base. A second hand contact surface extends from the first hand contact surface intermediate a leading and trailing ends of the base at an obtuse angle relative to the first hand contact surface.
摘要翻译： 用于与具有沿着孔轴线延伸的桶的枪支一起使用的枪械前部把手以及与所述筒操作地相关联并沿着所述孔轴线延伸的附接轨道。 枪支握柄包括构造成接合附接轨道的基座，该基座具有前端和后端。 第一手接触表面构造成从基座的前端基本上平行于附接轨道延伸。 第二手接触表面相对于第一手接触表面以钝角从第一手接触表面延伸到基部的前端和后端。
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公开(公告)号：US20110099879A1
公开(公告)日：2011-05-05
申请号：US12978153
申请日：2010-12-23
IPC分类号： F41C27/00
CPC分类号： F41C23/16 , F41A35/02 , F41G11/003
摘要： A panel system for covering a lengthwise segment of an elongate firearm mounting rail. The panel system comprises at least one pair of identically shaped panel halves. Each panel half comprises a body having a top, a bottom, an abutting proximal edge and a distal edge. At least one axial tongue extends from the abutting proximal edge and a corresponding axial groove having a groove mouth is defined in the body. A cantilevered clip extends from the abutting proximal edge. A clip receptacle is defined by the body. A proximally extending lip extends from the body bottom near the distal edge. Each panel half is configured so that with the abutting proximal edges brought into abutment, each axial tongue of each panel is received in a corresponding axial groove of the other and each cantilevered clip engages the clip receptacle of the other.
摘要翻译： 一种面板系统，用于覆盖细长火器安装轨道的纵向段。 面板系统包括至少一对相同形状的面板半部。 每个面板一半包括具有顶部，底部，邻接近侧边缘和远侧边缘的主体。 至少一个轴向舌片从邻接的近侧边缘延伸，并且在体内限定具有凹槽口的对应的轴向凹槽。 悬臂夹从邻接的近侧边缘延伸。 夹子容器由身体定义。 近端延伸的唇缘从远端边缘附近的身体底部延伸。 每个面板一半构造成使得邻接的近侧边缘被抵接，每个面板的每个轴向舌片被容纳在另一个的对应的轴向凹槽中，并且每个悬臂夹子与另一个的夹子容器接合。
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