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    COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF HYPERURICEMIA RELATED HEALTH CONSEQUENCES
    7.
    发明申请
    COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF HYPERURICEMIA RELATED HEALTH CONSEQUENCES 审中-公开
    治疗和预防高血压相关健康后果的组合物和方法

    公开(公告)号：US20160166573A1

    公开(公告)日：2016-06-16

    申请号：US14880412

    申请日：2015-10-12

    申请人： Richard Johnson ,  Takahiko Nakagawa

    发明人： Richard Johnson ,  Takahiko Nakagawa

    IPC分类号： A61K31/519 ,  A61K31/426

    CPC分类号： A61K31/519 ,  A61K31/426 ,  A61K31/4439

    摘要： Disclosed herein are methods of delaying the onset or treating diabetes that comprises administering a uric acid lowering agent. The inventors have made the remarkable discovery that elevated uric acid levels are not a corollary to insulin resistance, but rather a primary mediator of insulin resistance. Specifically exemplified are methods that involve administering to a patient susceptible to development of diabetes a composition comprising a uric acid lowering agent in a regimen that maintains serum uric acid levels below at least 5.5 mg/dl, or below at least 5.2 mg/dl.

    摘要翻译： 本文公开了延迟起效或治疗糖尿病的方法，其包括施用降低尿酸的试剂。 本发明人已经发现了显着的发现：升高的尿酸水平不是胰岛素抵抗的必然结果，而是胰岛素抵抗的主要介质。 具体举例说明的方法是涉及向患有糖尿病发展的患者施用包含尿酸降低剂的组合物的方法，其维持血清尿酸水平低于至少5.5mg / dl或低于至少5.2mg / dl。

    Confidential message exchange using benign, context-aware cover message generation
    9.
    发明授权
    Confidential message exchange using benign, context-aware cover message generation 有权
    使用良性，上下文感知覆盖消息生成的机密消息交换

    公开(公告)号：US08782409B2

    公开(公告)日：2014-07-15

    申请号：US13488391

    申请日：2012-06-04

    申请人： Shaun Murphy ,  Charles Murphy ,  Richard Johnson

    发明人： Shaun Murphy ,  Charles Murphy ,  Richard Johnson

    IPC分类号： H04L9/32

    CPC分类号： H04L63/123 ,  H04L51/18 ,  H04L51/24 ,  H04L63/04 ,  H04L63/0407 ,  H04L63/0428 ,  H04L63/0442 ,  H04L63/061 ,  H04L63/083 ,  H04L63/0876 ,  H04L63/12 ,  H04L63/1475 ,  H04L63/168

    摘要： Systems and methods are disclosed permitting a sender to send a secret and secure message to a recipient. An application on a sender device interfaces with known message generating tools to permit a user to generate a message. The local application encrypts the message (and optional attachments) based on public/private key pairing negotiated with the server given the recipient device id. The sender device transmits the cipher text to the server. The server generates a benign, text-based, context-appropriate message and delivers same to a recipient device by way of a known messaging service. The benign message provides a secret clue to the recipient that an encrypted message is available. Recipient may then access and decrypt the encrypted message, such as from the server in response to a successful challenge (e.g., password request).

    摘要翻译： 公开了允许发送者向接收者发送秘密和安全消息的系统和方法。 发件人设备上的应用程序与已知的消息生成工具接口，以允许用户生成消息。 本地应用程序基于与给定收件人设备ID的服务器协商的公钥/私钥配对来加密消息（和可选附件）。 发件人设备将密文发送到服务器。 服务器生成一种良性的，基于文本的上下文相关消息，并通过已知的消息传递服务将其传递给接收方设备。 良性消息为收件人提供了一条加密消息可用的秘密线索。 收件人然后可以响应于成功的挑战（例如，密码请求）来访问和解密加密的消息，诸如从服务器解密。