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公开(公告)号:US20050124618A1
公开(公告)日:2005-06-09
申请号:US10986695
申请日:2004-11-12
申请人: Richard Roman , Andrew Greene , Sandra Amaral , Alfonso Scicli , Stephen Brown
发明人: Richard Roman , Andrew Greene , Sandra Amaral , Alfonso Scicli , Stephen Brown
IPC分类号: A61K31/00 , A61K31/155 , A61K31/18 , A61K31/20 , A61K31/255 , A61K31/335 , A61K31/4174 , A61K31/4192 , A61K31/4196 , A61K31/496 , A61K31/537 , A61K31/5375
CPC分类号: A61K31/335 , A61K31/00 , A61K31/155 , A61K31/18 , A61K31/20 , A61K31/255 , A61K31/4174 , A61K31/4192 , A61K31/4196 , A61K31/496 , A61K31/537 , A61K31/5375
摘要: Methods for regulating angiogenesis by modulating the activity of 20-HETE are disclosed. Further disclosed are methods of inhibiting cancer and tumor cell growth by exposing the cancer and tumor cells to 20-HETE inhibitors.
摘要翻译: 公开了通过调节20-HETE的活性来调节血管生成的方法。 进一步公开的是通过将癌症和肿瘤细胞暴露于20-HETE抑制剂来抑制癌症和肿瘤细胞生长的方法。