Process for recovery and recycle of methanesulfonic acid and phosphorous
acid
    2.
    发明授权
    Process for recovery and recycle of methanesulfonic acid and phosphorous acid 失效
    甲磺酸和亚磷酸的回收和再循环方法

    公开(公告)号:US5589691A

    公开(公告)日:1996-12-31

    申请号:US254213

    申请日:1994-06-06

    IPC分类号: C02F1/52 C07F9/38 C09K3/00

    CPC分类号: C07F9/3873

    摘要: Disclosed is a process for recovering and recycling waste methanesulfonic acid (MSA) and phosphorous acid (H.sub.3 PO.sub.3) in a bisphosphonation process for reuse in the process. The recovery process involves treating a waste crude mother liquor stream with HCl to remove sodium ion, as sodium chloride, recovering HCl--H.sub.2 O by atmospheric distillation, separating and dehydrating a mixture of methanesulfonic acid and phosphorous acid by vacuum distillation for recycle. The substantially dry methanesulfonic acid and phosphorous acid, and previous HCl, can all be recycled back to the process for reuse.

    摘要翻译: 公开了一种在二膦酸化方法中回收和回收废甲烷磺酸(MSA)和亚磷酸(H 3 PO 3)以在该方法中再利用的方法。 回收过程包括用HCl处理废粗母液流以除去钠离子,作为氯化钠,通过常压蒸馏回收HCl-H 2 O,通过真空蒸馏分离和脱水甲磺酸和亚磷酸的混合物以进行再循环。 基本上干燥的甲磺酸和亚磷酸以及先前的HCl都可以循环回该过程进行再利用。

    Process for removing waste pox, alendronate and its by products
    3.
    发明授权
    Process for removing waste pox, alendronate and its by products 失效
    去除废痘,阿仑膦酸及其副产物的方法

    公开(公告)号:US5449819A

    公开(公告)日:1995-09-12

    申请号:US254805

    申请日:1994-06-06

    摘要: Disclosed is a process for removing by-product phosphorus-containing (PO.sub.x) materials, alendronate and alendronate byproducts from crude mother liquors in an omega amino-1-hydroxy-C.sub.2 -C.sub.6 alkylidene-1,1-bisphosphonic acid synthesis process, e.g. alendronate sodium. Calcium chloride is added first to the crude mother liquors, then calcium oxide to precipitate the PO.sub.x materials, then neutralized to about pH 7 to complete precipitation. Substantially all of the alendronate sodium active ingredient is removed from the precipitate. Following filtration, the PO.sub.x filtercake can then be disposed of by incineration, landfilling or reclamation of usable phosphorus as fertilizer. The remaining filtrate can then be further treated in an environmentally acceptable manner by wastewater treatment or recycling to the process.

    摘要翻译: 公开了一种在ω-氨基-1-羟基-C 2 -C 6亚烷基-1,1-二膦酸合成方法中从粗制母液中除去副产物含磷(POx)材料,阿仑膦酸盐和阿仑膦酸盐副产物的方法,例如。 阿仑膦酸钠。 首先将氯化钙加入到粗制母液中,然后加入氧化钙沉淀POx物质,然后中和至约pH 7以完成沉淀。 基本上将所有的阿仑膦酸钠活性成分从沉淀物中除去。 过滤后,然后通过焚烧,填埋或回收可用磷作为肥料来处理POx滤饼。 然后可以以环境可接受的方式通过废水处理或再循环到该方法来进一步处理剩余的滤液。