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公开(公告)号:US20070111988A1
公开(公告)日:2007-05-17
申请号:US10597008
申请日:2005-01-18
申请人: Robert Dally , Jeffrey Dodge , Conrad Hummel , Scott Jones , Timothy Shepherd , Owen Wallace , Wayne Weber
发明人: Robert Dally , Jeffrey Dodge , Conrad Hummel , Scott Jones , Timothy Shepherd , Owen Wallace , Wayne Weber
IPC分类号: A61K31/55 , A61K31/453 , C07D409/02 , A61K31/445
CPC分类号: C07D209/46 , C07D209/48 , C07D295/088 , C07D295/192 , C07D307/83 , C07D311/78 , C07D333/64 , C07D409/04
摘要: The present invention relates to a selective estrogen receptor modulators of formula I (I); or a pharmaceutical acid addition salt thereof; and of formula II (II); or a pharmaceutical salt thereof; useful, e.g., for treating endometriosis and/or uterine leiomyoma/leiomyomata.
摘要翻译: 本发明涉及式I(I)的选择性雌激素受体调节剂; 或其药用酸加成盐; 和式II(II); 或其药学盐; 有用的,例如用于治疗子宫内膜异位症和/或子宫平滑肌瘤/平滑肌瘤。
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公开(公告)号:US6046052A
公开(公告)日:2000-04-04
申请号:US65930
申请日:1998-04-24
申请人: Thomas Arter , David B. LaTart , John C. Mauck , Richard C. Sutton , Wayne Weber , Robert Winterkorn , James Schaeffer
发明人: Thomas Arter , David B. LaTart , John C. Mauck , Richard C. Sutton , Wayne Weber , Robert Winterkorn , James Schaeffer
CPC分类号: G01N33/6827 , G01N33/525 , G01N33/683 , G01N33/6839
摘要: A dry analytical element is disclosed which can be used to sensitively and rapidly detect and quantitate protein. The assays are carried out using a dye that reacts with protein and molybdate ion to produce a measurable change in the spectral absorption of the dye. Also disclosed are polymers which stabilize and enhance the accuracy of the assay, and compounds which reduce interference by bicarbonate.
摘要翻译: 公开了可用于敏感和快速检测和定量蛋白质的干燥分析元件。 使用与蛋白质和钼酸根离子反应的染料进行测定以产生染料的光谱吸收的可测量的变化。 还公开了稳定和提高测定精度的聚合物,以及减少碳酸氢盐干扰的化合物。
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