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公开(公告)号:US20130157375A1
公开(公告)日:2013-06-20
申请号:US13643198
申请日:2011-04-27
申请人: Robert Hider , Yongmin Ma , Ulrich Schaible , Maria Podinovskaia
发明人: Robert Hider , Yongmin Ma , Ulrich Schaible , Maria Podinovskaia
IPC分类号: C07D213/68 , C07D405/14 , C07D401/14 , C07D405/12 , C07D401/12
CPC分类号: C07D213/68 , C07B2200/11 , C07D213/69 , C07D309/40 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , G01N33/90
摘要: In one aspect, there is provided a fluorescent iron-binding compound bound to a solid phase. Also provided is a method for detecting non-transferrin bound iron in a sample, comprising contacting the sample with a fluorescent iron-binding compound bound to a solid phase and detecting a fluorescent signal derived from the fluorescent iron-binding compound bound to the solid phase, wherein the fluorescent signal is indicative of non-transferrin bound iron levels in the sample. Further provided is use of a fluorescent iron-binding compound bound to a solid phase to detect non-transferrin bound iron in a sample.
摘要翻译: 在一个方面,提供了结合到固相的荧光铁结合化合物。 还提供了一种用于检测样品中非转铁蛋白结合铁的方法,包括使样品与结合到固相的荧光铁结合化合物接触并检测衍生自与固相结合的荧光铁结合化合物的荧光信号 ,其中荧光信号指示样品中非转铁蛋白结合的铁水平。 进一步提供使用与固相结合的荧光铁结合化合物来检测样品中非转铁蛋白结合铁。