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1.发明申请Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems 有权氟化合物通过光化学或化学方法转化为荧光团，并在生物系统中的应用公开(公告)号：US20100029952A1
公开(公告)日：2010-02-04
申请号：US12454273
申请日：2009-05-13
申请人： Robert J. Tweg , William E. Moerner , Samuel J. Lord , Na Liu , Reichel Samuel
发明人： Robert J. Tweg , William E. Moerner , Samuel J. Lord , Na Liu , Reichel Samuel
IPC分类号： C07D213/02 , C07D307/02 , C07D249/04 , C07D271/12
CPC分类号： C07D307/30 , C07D213/42 , C07D249/16 , C07D265/38 , C07D271/12 , C07D309/34 , Y10S436/80
摘要： Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells.
摘要翻译： 公开了衍生自可光活化叠氮受体氟原子的荧光团或来自叠氮受体氟原子与烯烃或炔烃的热反应。 还公开了衍生自炔 - 吡啶受体氟原子与叠氮化物的热反应的荧光团。 荧光团可以容易地被光激活，并且可以用于标记生物分子并在活细胞中在单分子水平上成像。
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2.发明授权Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems 有权氟化合物通过光化学或化学方法转化为荧光团，并在生物系统中的应用公开(公告)号：US08153446B2
公开(公告)日：2012-04-10
申请号：US12454273
申请日：2009-05-13
申请人： Robert J. Twieg , William E. Moerner , Samuel J. Lord , Na Liu , Reichel Samuel
发明人： Robert J. Twieg , William E. Moerner , Samuel J. Lord , Na Liu , Reichel Samuel
IPC分类号： G01N33/53
CPC分类号： C07D307/30 , C07D213/42 , C07D249/16 , C07D265/38 , C07D271/12 , C07D309/34 , Y10S436/80
摘要： Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells.
摘要翻译： 公开了衍生自可光活化叠氮受体氟原子的荧光团或来自叠氮受体氟原子与烯烃或炔烃的热反应。 还公开了衍生自炔 - 吡啶受体氟原子与叠氮化物的热反应的荧光团。 荧光团可以容易地被光激活，并且可以用于标记生物分子并在活细胞中在单分子水平上成像。
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3.发明授权Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems 失效氟化合物通过光化学或化学方法转化为荧光团，并在生物系统中的应用公开(公告)号：US08772048B2
公开(公告)日：2014-07-08
申请号：US13409818
申请日：2012-03-01
申请人： Robert J. Twieg , William E. Moerner , Samuel J. Lord , Na Liu , Reichel Samuel
发明人： Robert J. Twieg , William E. Moerner , Samuel J. Lord , Na Liu , Reichel Samuel
IPC分类号： G01N33/533 , G01N33/532 , C07K1/10
CPC分类号： C07D307/30 , C07D213/42 , C07D249/16 , C07D265/38 , C07D271/12 , C07D309/34 , Y10S436/80
摘要： Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells.
摘要翻译： 公开了衍生自可光活化叠氮受体氟原子的荧光团或来自叠氮受体氟原子与烯烃或炔烃的热反应。 还公开了衍生自炔 - pi受体氟原子与叠氮化物的热反应的荧光团。 荧光团可以容易地被光激活，并且可以用于标记生物分子并在活细胞中在单分子水平上成像。
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