Direct Imaging of Neural Currents Using Ultra-Low Field Magnetic Resonance Techniques
    2.
    发明申请
    Direct Imaging of Neural Currents Using Ultra-Low Field Magnetic Resonance Techniques 有权
    使用超低场磁共振技术直接成像神经电流

    公开(公告)号:US20070252595A1

    公开(公告)日:2007-11-01

    申请号:US11678023

    申请日:2007-02-22

    IPC分类号: A61B5/055

    CPC分类号: A61B5/055

    摘要: Using resonant interactions to directly and tomographically image neural activity in the human brain using magnetic resonance imaging (MRI) techniques at ultra-low field (ULF), the present inventors have established an approach that is sensitive to magnetic field distributions local to the spin population in cortex at the Larmor frequency of the measurement field. Because the Larmor frequency can be readily manipulated (through varying Bm), one can also envision using ULF-DNI to image the frequency distribution of the local fields in cortex. Such information, taken together with simultaneous acquisition of MEG and ULF-NMR signals, enables non-invasive exploration of the correlation between local fields induced by neural activity in cortex and more ‘distant’ measures of brain activity such as MEG and EEG.

    摘要翻译: 本发明人利用超低场(ULF)中的磁共振成像(MRI)技术直接使用共振相互作用和层析成像对人脑中的神经活动图像,建立了对旋转群体局部的磁场分布敏感的方法 在皮质中的拉莫尔频率测量领域。 由于Larmor频率可以容易地被操纵(通过变化的B> m),所以也可以设想使用ULF-DNI对皮层中的局部场的频率分布进行成像。 这些信息与MEG和ULF-NMR信号的同时采集一起使得能够非侵入性地探索由皮层神经活动引起的局部区域与脑活动(例如MEG和EEG)的更远的“测量”之间的相关性。