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公开(公告)号:US07994351B2
公开(公告)日:2011-08-09
申请号:US12613969
申请日:2009-11-06
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
摘要翻译: 提供了制备脱氧胆酸的合成方法及其中间体。
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公开(公告)号:US20130137884A1
公开(公告)日:2013-05-30
申请号:US13140421
申请日:2010-12-17
IPC分类号: C07J9/00
CPC分类号: C07J9/005 , A61K31/575 , C07J1/0011 , C07J5/0053 , C07J9/00 , C07J13/007 , C07J41/0061 , Y02P20/55
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxy-steroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
摘要翻译: 提供了制备脱氧胆酸的合成方法及其中间体,提供了高纯合成脱氧胆酸,组合物和使用方法。 此外,提供了用于合成来自Delta-9,11-烯,11-酮基或11-羟基-β-类固醇的12-酮或12-α-羟基甾族化合物的方法。 本发明还涉及在合成过程中制备的新型化合物。 本发明还涉及从氢化可的松开始脱氧胆酸的合成。
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公开(公告)号:US08362285B2
公开(公告)日:2013-01-29
申请号:US13010727
申请日:2011-01-20
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号:US07902387B2
公开(公告)日:2011-03-08
申请号:US12153446
申请日:2008-05-16
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
IPC分类号: C07J9/00
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号:US20130267721A1
公开(公告)日:2013-10-10
申请号:US13752175
申请日:2013-01-28
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
IPC分类号: C07J9/00
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号:US20110224448A1
公开(公告)日:2011-09-15
申请号:US13115889
申请日:2011-05-25
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
IPC分类号: C07J9/00
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号:US20110152552A1
公开(公告)日:2011-06-23
申请号:US13010727
申请日:2011-01-20
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
摘要翻译: 提供了制备脱氧胆酸的合成方法及其中间体。
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公开(公告)号:US08367852B2
公开(公告)日:2013-02-05
申请号:US13115889
申请日:2011-05-25
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
IPC分类号: C07J9/00
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号:US20100145083A1
公开(公告)日:2010-06-10
申请号:US12613969
申请日:2009-11-06
申请人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
发明人: Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号:US20090270642A1
公开(公告)日:2009-10-29
申请号:US12153446
申请日:2008-05-16
CPC分类号: C07J9/005 , C07J1/00 , C07J1/0011 , C07J9/00 , C07J13/00 , C07J13/007 , C07J75/00
摘要: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
摘要翻译: 提供了制备脱氧胆酸的合成方法及其中间体。
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