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    METHOD FOR PRODUCING y-ORYZANOL-CONTAINING FAT OR OIL
    1.
    发明申请
    METHOD FOR PRODUCING y-ORYZANOL-CONTAINING FAT OR OIL 审中-公开
    用于生产含有YYOYZANOL的脂肪或油的方法

    公开(公告)号：US20130237508A1

    公开(公告)日：2013-09-12

    申请号：US13881448

    申请日：2011-11-08

    申请人： Takuo Tsuno ,  Takashi Yamanaka ,  Hiroaki Segoshi

    发明人： Takuo Tsuno ,  Takashi Yamanaka ,  Hiroaki Segoshi

    IPC分类号： A61K31/575

    CPC分类号： A61K31/575 ,  A23D9/007 ,  A23K20/158 ,  A23L33/115 ,  C07J13/00 ,  C11B3/04 ,  C11B3/06 ,  C11B5/0035 ,  C11B13/02 ,  Y02W30/74

    摘要： The disclosed method for producing a γ-oryzanol-containing fat or oil, the method comprising the steps of: (A) preparing a processed fat or oil having an oil layer and a soapstock (alkali-foots) layer containing a γ-oryzanol salt; and (B) adding an acid to the processed fat or oil of step (A) for transfer of γ-oryzanol from the soapstock layer to the oil layer, and collecting a fat or oil with an increased γ-oryzanol content, enables inexpensive production of a fat or oil containing γ-oryzanol at any desired concentration without restriction to the γ-oryzanol concentration in the raw fat or oil.

    摘要翻译： 所公开的含有γ-谷维素的脂肪或油的制造方法，该方法包括以下步骤：（A）制备含有油层的加工油脂和含有γ-谷维素盐的皂片（碱 - 脚）层 ; 和（B）向步骤（A）的经加工的脂肪或油中加入酸，以将γ-谷维素从皂液层转移到油层，并收集具有增加的γ-谷维素含量的脂肪或油，使得可以廉价地生产 的含有γ-谷维素的脂肪或油以任何所需浓度，而不限于生的脂肪或油中的γ-谷维素浓度。

    Fusidic acid derivatives
    6.
    发明授权
    Fusidic acid derivatives 失效
    夫西地酸衍生物

    公开(公告)号：US4100276A

    公开(公告)日：1978-07-11

    申请号：US744978

    申请日：1976-11-24

    申请人： Welf von Daehne ,  Poul Rodbroe Rasmussen

    发明人： Welf von Daehne ,  Poul Rodbroe Rasmussen

    IPC分类号： C07J9/00 ,  A61K31/575 ,  A61P31/04 ,  C07J13/00 ,  C07J17/00 ,  C07J31/00 ,  C07J41/00 ,  C07J51/00 ,  A61K31/56

    CPC分类号： C07J51/00 ,  C07J13/00 ,  C07J31/003 ,  C07J41/0088

    摘要： The invention relates to a new series of fusidic acid derivatives, to salts and easily hydrolyzable esters thereof, to the preparation of these compounds and to pharmaceutical compositions containing the compounds, the new compounds having the general formula: ##STR1## in which Q.sub.1 and Q.sub.2 stand for the group ##STR2## or oxygen, A represents oxygen or sulphur, and R.sub.1 stands for a straight or branched alkyl radical having from 1 to 12 carbon atoms, R.sub.1 can further be an alkenyl or alkynyl radical having from 3 to 6 carbon atoms, a cycloalkyl radical having from 3 to 7 carbon atoms in the alicyclic ring, an aralkyl or aryl radical, R.sub.1 can also be a heterocyclic radical having 5 or 6 ring atoms and containing oxygen, sulphur and/or nitrogen atoms, R.sub.1 optionally being further substituted, and in which formula I the dotted line between C-24 and C-25 indicates that the carbon atoms in question are connected by either a double bond or a single bond, and the asterix at C-20 indicates that the compounds exist in two diastereomeric forms, and thus the invention comprises the pure diastereomers as well as mixtures of these.The compounds of the present invention possess antibacterial properties and show further interesting antimicrobial and pharmacokinetic properties.

    摘要翻译： 本发明涉及新的一系列夫西地酸衍生物，其盐和容易水解的酯，用于制备这些化合物和含有该化合物的药物组合物，具有以下通式的新化合物：其中Q1和 Q2代表组或氧，A表示氧或硫，R1表示具有1至12个碳原子的直链或支链烷基，R1可以进一步为具有3-6个碳原子的烯基或炔基 原子，脂环中具有3至7个碳原子的环烷基，芳烷基或芳基，R 1也可以是具有5或6个环原子并含有氧，硫和/或氮原子的杂环基，R 1可任选地为 并且其中式I中C-24和C-25之间的虚线表示所讨论的碳原子通过双键或单键连接，C-20处的星号表示com 磅以两种非对映体形式存在，因此本发明包括纯非对映异构体以及它们的混合物。