摘要:
The present invention relates to a method of ultra- and dialfiltrating an antibody solution containing at least one solute in addition to the antibody, which comprises diafiltrating the antibody solution with a solvent and bringing said mixture into contact with a semi-permeable membrane so as to allow the at least one solute present in the antibody solution and having a molecular weight lower than the molecular weight cut-off of the membrane to pass through the membrane, whilst retaining the antibody so that a modified antibody solution is obtained that only contains the antibody and the solvent.
摘要:
A method for operating a machine that processes printing substrates in sheet form, in particular, a printing press, including a delivery device (1) which contains a drive (2) for conveying the substrate sheets and at least one opening (8) through which the substrate sheets are conveyed from the inside (4) of the delivery device (1) to an externally accessible region (6), and further including a control device which controls at least one closing device (7) for opening or closing the opening (8) and which is operatively connected to the drive (2) of the delivery device (1). Also provided is a device for carrying out the method. The present invention has the feature that the opening (8) is closed or is closed by the control device when no substrate sheet is conveyed through the opening (8).
摘要:
A circuit breaker includes a molded base and cover, with at least one of the base and cover being a molded member including a pair of end walls, a pair of side walls, and an opening between the side walls. A strengthening member engages the base and cover between the side walls at the opening, engages at least one of the side walls and is an interior wall of the molded member. The base and cover are made of a first material, such as glass polyester or a suitably high strength plastic, and the strengthening member is made of a second dissimilar material, such as aluminum or steel, which has greater strength than the first material. An operating mechanism coupled to separable contacts is structured to move the contacts between open and closed positions. A trip mechanism coupled to the operating mechanism is structured to actuate the operating mechanism.
摘要:
The invention relates to a lyophilised pharmaceutical preparation comprising an antibody against the endothelial growth factor receptor (EGF receptor). The preparation has increased storage stability, even at elevated temperatures, and, after reconstitution, can be used parenterally for the treatment of tumours.
摘要:
An arrangement for a four wheel drive motor vehicle which increases the rotational moment transfer from the front axle to the rear axle in the case of a large rotational speed differential between the two axles. The arrangement includes a lamella or plate clutch arranged between the front axle and the rear axle. The front axle is directly driven by the gear change transmission and the rear axle is indirectly driven by the front axle. A one way clutch and a reducing transmission are interposed with respect to the plate clutch in such a way that the characteristic curve for rotational moment transfer versus axle rotational speed differential exhibits a flat slope during normal driving conditions (relatively small speed differentials) and an increasingly steep slope during hazardous driving conditions (relatively large speed differentials).
摘要:
This invention relates to sustained release liquid pharmaceutical compositions containing a peptide analogue of glucagon-like peptide-1 or salts thereof having an improved release profile. The invention also relates to methods for preparing such compositions.