-
公开(公告)号:US20070009198A1
公开(公告)日:2007-01-11
申请号:US11174123
申请日:2005-07-01
申请人: Robert Petcavich , Xiaoping Simon Yang , Xuanqi John Zhang , Dan Jin , Nick Wolf , Timothy Londergan , Diyun Huang , Galina Todorova
发明人: Robert Petcavich , Xiaoping Simon Yang , Xuanqi John Zhang , Dan Jin , Nick Wolf , Timothy Londergan , Diyun Huang , Galina Todorova
IPC分类号: G02B6/00
CPC分类号: G01N33/54373 , G01N21/6428 , G01N21/648 , G01N21/7703 , G02B6/0008 , G02B6/02033
摘要: A bio-sensor that includes (a) an optical fiber in which the surface of the fiber comprises a hydrogel polymer that includes a functional group comprising a first member of a binding pair; and (b) an excitation light source coupled to the fiber. When the fiber contacts a solution comprising a second member of the binding pair labeled with a light-emitting label, the first member binds to the second member, resulting in the emission of a detectable signal. Alternatively, the first member of the binding pair is provided with the light-emitting label.
摘要翻译: 一种生物传感器,其包括(a)光纤,其中所述纤维的表面包含水凝胶聚合物,所述水凝胶聚合物包括包含结合对的第一成员的官能团; 和(b)耦合到所述光纤的激发光源。 当纤维接触包含用发光标签标记的结合对的第二个成员的溶液时,第一个成员结合第二个成员,导致发出可检测的信号。 或者,绑定对的第一构件设置有发光标签。