公开(公告)号：US20200003666A1

公开(公告)日：2020-01-02

申请号：US16569700

申请日：2019-09-13

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Eloisa Lopez-Calle ,  Ewelina Hegel ,  Thomas Fischer ,  Caroline Bylda ,  Hans-Peter Josel ,  Josef Roedl

IPC: G01N1/40 ,  G01N33/74 ,  G01N33/82 ,  G01N33/94

Abstract: The present disclosure relates to an in vitro method for releasing analytes from a sample involving contacting the sample with (i) a chaotropic agent, (ii) an organic solvent, (iii) a detergent, and (iv) at least one agent providing bicarbonate ions. The present disclosure further relates to a release agent for releasing analytes from a sample having the aforesaid compounds. Moreover, the present disclosure relates to uses, kits, methods and devices related to the method and the release agent of the present disclosure.