公开(公告)号：US20200041502A1

公开(公告)日：2020-02-06

申请号：US16599480

申请日：2019-10-11

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Jens Christian Bolle ,  Martin Eduardo Silvestre ,  Stephan Hug ,  Carolyn Bylda

IPC: G01N33/543 ,  G01N33/553 ,  B01J13/14 ,  B03C1/01

Abstract: The present disclosure relates to magnetic particles, wherein each particle has a polymer matrix and at least one magnetic core (M), wherein the polymer matrix has at least one crosslinked polymer and wherein the magnetic particle has a particle size in the range of from 1 to 60 micrometer. Further, the present disclosure relates to a method of preparing such particles, and to particles obtainable or obtained by said method. Moreover, the present disclosure uses these magnetic particles for qualitative and/or quantitative determination of at least one analyte in a fluid. Further, the present disclosure relates to a method for determining at least one analyte in a fluid sample using the contacting of a magnetic particle of the disclosure or a magnetic particle obtained by the method of the present disclosure with a fluid sample having or suspected to have the at least one analyte.