公开(公告)号：US20150080689A1

公开(公告)日：2015-03-19

申请号：US14462990

申请日：2014-08-19

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Otto Fuerst

IPC: A61B5/1486 ,  C25D9/02

CPC classification number: A61B5/1486 ,  C12Q1/001 ,  C12Q1/004 ,  C12Q1/006 ,  C25D9/02

Abstract: A method for making a dry sensor element for an enzymatic determination of an analyte in a body fluid includes providing a substrate, producing a working electrode on the substrate, producing a counter electrode on the substrate, and producing electric connectors on the substrate connected to the working electrode and the counter electrode, the step of producing the working electrode further comprising depositing an active enzymatic electrode layer containing an enzyme and a catalyzer material for catalyzing an enzymatic determination of an analyte of a body fluid, the catalyzer material comprising at least one of metal nano-particles and metal oxide nano-particles. A dry sensor element for an enzymatic determination of an analyte in a body fluid is also disclosed.

Abstract translation: 一种用于制造用于体液中的分析物的酶测定的干燥传感器元件的方法包括：提供基板，在所述基板上产生工作电极，在所述基板上产生对电极，以及在与所述基板连接的基板上产生电连接器 工作电极和对电极，制备工作电极的步骤还包括沉积含有酶和催化剂材料的活性酶电极层，用于催化体液的分析物的酶测定，所述催化剂材料包含至少一种 金属纳米颗粒和金属氧化物纳米颗粒。 还公开了用于酶测定体液中的分析物的干燥传感器元件。

公开(公告)号：US20140083872A1

公开(公告)日：2014-03-27

申请号：US14087347

申请日：2013-11-22

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Otto Fuerst ,  Johannes Pill ,  Bernd Roesicke

IPC: G01N27/327

CPC classification number: G01N27/3271 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14735 ,  G01N27/3276 ,  G01N27/403 ,  G01N27/404 ,  G01N27/4145 ,  G01N33/54366

Abstract: A sensor device for detecting at least one analyte in a fluid, in particular in a body fluid, is disclosed. The sensor device includes at least one closed detector chamber and at least one electrical sensor having at least one sensor electrode. The detector chamber can be connected to the fluid in such a way that the analyte can penetrate into the detector chamber. The detector chamber includes at least one detector substance. The detector substance is designed to influence at least one electrical property of the electrical sensor, in particular at least one electrical property of the sensor electrode, depending on a concentration of the analyte in the detector chamber.

Abstract translation: 公开了一种用于检测流体，特别是体液中的至少一种分析物的传感器装置。 传感器装置包括至少一个闭合检测器室和至少一个具有至少一个传感器电极的电传感器。 检测器室可以以这样的方式连接到流体，使得分析物可以渗透到检测器室中。 检测器室包括至少一个检测器物质。 检测器物质被设计成根据检测器室中的分析物的浓度来影响电传感器的至少一个电特性，特别是传感器电极的至少一个电特性。