公开(公告)号：US20160018411A1

公开(公告)日：2016-01-21

申请号：US14639496

申请日：2015-03-05

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Christoph Ehret ,  Johann Karl ,  Ralf Roeddiger ,  Wolfgang Rollinger ,  Magdalena Swiatek-de Lange

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  A61B5/0205 ,  G01N2333/96411 ,  G01N2333/96433 ,  G01N2800/12 ,  G01N2800/32

Abstract: The present invention relates to a method for differentiating in a patient who suffers from acute shortness of breath (acute dyspnea) between pulmonary disease and cardiac disease. The method is based on measuring the levels of seprase and of a cardiac marker in a sample from said patient. Further envisaged are kits and devices adapted to carry out the method of the present invention.

Abstract translation: 本发明涉及在患有肺疾病与心脏病之间的急性呼吸急促（急性呼吸困难）的患者中进行区分的方法。 该方法基于测量来自所述患者的样品中seprase和心脏标志物的水平。 进一步设想的是适于实施本发明方法的试剂盒和装置。

公开(公告)号：US20170115294A1

公开(公告)日：2017-04-27

申请号：US15399801

申请日：2017-01-06

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Norbert Wild ,  Ursula Garczarek ,  Andrea Geistanger ,  Herbert Andres ,  Marie-Luise Hagmann ,  Johann Karl ,  Freidemann Krause ,  Michael Pfeffer ,  Wolfgang Rollinger ,  Michael Tacke ,  Michael Thierolf

IPC: G01N33/574

CPC classification number: G01N33/57419 ,  C12Q1/6886 ,  G01N2333/4727 ,  G01N2333/805 ,  G01N2333/8146 ,  G01N2333/9121

Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein S100A12 in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a stool sample, derived from an individual by measuring S100A12 in said sample. Measurement of S100A12 can, e.g., be used in the early detection or diagnosis of colorectal cancer.

公开(公告)号：US20150192587A1

公开(公告)日：2015-07-09

申请号：US14463975

申请日：2014-08-20

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Norbert Wild ,  Ursula Garczarek ,  Andrea Geistanger ,  Herbert Andres ,  Marie-Luise Hagmann ,  Johann Karl ,  Friedemann Krause ,  Michael Pfeffer ,  Wolfgang Rollinger ,  Michael Tacke ,  Michael Thierolf

IPC: G01N33/574

CPC classification number: G01N33/57419 ,  C12Q1/6886 ,  G01N2333/4727 ,  G01N2333/805 ,  G01N2333/8146 ,  G01N2333/9121

Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein S100A12 in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a stool sample, derived from an individual by measuring S100A12 in said sample. Measurement of S100A12 can, e.g., be used in the early detection or diagnosis of colorectal cancer.