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公开(公告)号:US4260628A
公开(公告)日:1981-04-07
申请号:US78855
申请日:1979-09-26
IPC分类号: A61K31/40 , A61K31/403 , A61K31/404 , A61P9/12 , C07D209/14
CPC分类号: C07D209/14
摘要: 2-Guanidinomethyl-indolines of the formula ##STR1## wherein R.sup.1 and R.sup.2 each independently is H or alkyl of 1-6 carbon atoms, and the physiologically acceptable acid addition salts thereof have good antihypertensive properties.This is a division of application Ser. No. 939,046 filed Sept. 1, 1978, now abandoned.
摘要翻译: 其中R1和R2各自独立地为H或1-6个碳原子的烷基,其生理学上可接受的酸加成盐具有良好的抗高血压性质。
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公开(公告)号:US4289768A
公开(公告)日:1981-09-15
申请号:US145652
申请日:1980-05-02
IPC分类号: C07D417/06 , A61K31/54 , A61K31/5415 , A61P7/10 , A61P9/12 , C07D417/12 , C07D521/00 , A61K31/415 , C07D279/30
CPC分类号: C07D231/12 , C07D233/56 , C07D249/08
摘要: Phenothiazine derivatives of the formula ##STR1## wherein R is H, F, Cl, Br, I, CH.sub.3, CF.sub.3, CN, CH.sub.3 O or CH.sub.3 CO; Y is S, SO, or SO.sub.2 ; Z is imidazol-1-yl, 2-methyl-imidazol-1-yl, pyrazol-1-yl or benzimidazol-1-yl; and n is 1, 2 or 3; or the physiologically acceptable acid addition salts thereof; are useful as antihypertensive agents, for example.
摘要翻译: 其中R是H,F,Cl,Br,I,CH 3,CF 3,CN,CH 3 O或CH 3 CO的式IV的吩噻嗪衍生物; Y是S,SO或SO2; Z是咪唑-1-基,2-甲基 - 咪唑-1-基,吡唑-1-基或苯并咪唑-1-基; n为1,2或3; 或其生理上可接受的酸加成盐; 例如可用作抗高血压药。
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公开(公告)号:US4590180A
公开(公告)日:1986-05-20
申请号:US487645
申请日:1983-04-22
申请人: Klaus Irmscher , Rochus Jonas , Jurgen Uhl , Ernst Schorscher
发明人: Klaus Irmscher , Rochus Jonas , Jurgen Uhl , Ernst Schorscher
IPC分类号: C07H19/167 , A61K31/70 , A61K31/7042 , A61K31/7052 , A61K31/7076 , A61P25/00 , A61P25/08 , C07H19/16
CPC分类号: C07H19/16
摘要: Adenosine derivatives of formula I ##STR1## wherein X is F, Cl or Br and n is 1 or 2, and their physiologically acceptable acid addition salts, are valuable psychopharmacological agents.
摘要翻译: 式I的腺苷衍生物(I)其中X是F,Cl或Br,n是1或2,并且它们的生理上可接受的酸加成盐是有价值的精神药理学药剂。
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