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7 条记录 (耗时 0.021 秒)

    Preparation of piperidinylcyclopentylheptenoic acid derivatives
    1.
    发明授权
    Preparation of piperidinylcyclopentylheptenoic acid derivatives 失效
    哌啶基环戊烯庚酸衍生物的制备

    公开(公告)号：US4835278A

    公开(公告)日：1989-05-30

    申请号：US7670

    申请日：1987-01-28

    申请人： Roger Barrett ,  Clive A. Meerholz ,  Brian D. Judkins

    发明人： Roger Barrett ,  Clive A. Meerholz ,  Brian D. Judkins

    IPC分类号： C07D211/14 ,  B01J27/10 ,  B01J27/125 ,  B01J27/138 ,  C07B61/00 ,  C07D295/14 ,  C07D295/155

    CPC分类号： C07D295/155

    摘要： A process is described for the preparation of a compound of formula (2) ##STR1## (wherein R is a C.sub.1-6 alkyl or a C.sub.7-20 aralkyl group) and the salts thereof, which comprises reducing a compound of formula (3) ##STR2## (or a salt thereof), using a reducing system comprising borohydride ions and metal ions selected from lanthanide ions, alkaline earth metal ions or yttrium ions in solution. The reduction system may be provided by a borohydride (e.g. NaBH.sub.4) and a metal salt (e.g. CeCl.sub.3).The ester (2) may then if desired be hydrolyzed to give the parent acid.

    摘要翻译： 描述了制备式（2）化合物（2）（其中R是C 1-6烷基或C 7-20芳烷基）及其盐的方法，其包括将式 （3）使用包含选自镧系元素离子，碱土金属离子或钇离子的硼氢化物离子和金属离子的还原体系（或其盐）。 还原体系可以由硼氢化物（例如NaBH 4）和金属盐（例如CeCl 3）提供。 然后，如果需要，酯（2）可水解以得到母体酸。

    Process for Preparing a Co-Precipitate of a Non-Crystalline Solid Drug Substance
    3.
    发明申请
    Process for Preparing a Co-Precipitate of a Non-Crystalline Solid Drug Substance 审中-公开
    制备非结晶固体药物的共沉淀物的方法

    公开(公告)号：US20070082919A1

    公开(公告)日：2007-04-12

    申请号：US10575208

    申请日：2004-10-12

    申请人： Roger Barrett ,  Richard Ward

    发明人： Roger Barrett ,  Richard Ward

    IPC分类号： A61K31/522

    CPC分类号： A61K9/146 ,  A61K9/145 ,  A61K31/522

    摘要： The present invention provides processes for preparing co-precipitates of non-crystalline, solid drug substances, such as (E)-4-(1,3-bis(cyclohexylmethyl)-1,2,3,6 -tetrahydro-2,6-dioxo-9H-purin-8-yl)cinnamic acid nonaethylene glycol methyl ether ester and solvates thereof.

    摘要翻译： 本发明提供了制备非结晶固体药物的共沉淀物的方法，例如（E）-4-（1,3-双（环己基甲基）-1,2,3,6-四氢-2,6 - 二氧代-9H-嘌呤-8-基）肉桂酸九乙二醇甲基醚酯及其溶剂合物。

    Hazard detector
    4.
    发明申请
    Hazard detector 有权
    危险检测仪

    公开(公告)号：US20060220891A1

    公开(公告)日：2006-10-05

    申请号：US10541434

    申请日：2004-01-05

    申请人： Roger Barrett ,  Jeffrey Cutler

    发明人： Roger Barrett ,  Jeffrey Cutler

    IPC分类号： G08B29/18

    CPC分类号： G08B29/24 ,  G08B29/145

    摘要： A hazard detector has an electronic circuit with a start-up program for causing emission of a local indicator signal, such as a flashing signal from a LED, if power and ground terminals of the detector are connected with proper orientation, i.e. polarity, to power and ground lines of a power supply. Through this means, a person installing the hazard detector can tell immediately after connection if the detector has been connected with proper orientation, and avoids the need for introducing a hazard such as heat or smoke to test the operation of the detector. A variation uses a more sophisticated program that disables, during a test mode, complex filtering algorithms that are used by detectors to block false alarm signals; if such filtering is not disabled, impedes normal testing of the detectors.

    摘要翻译： 危险检测器具有电子电路，其具有启动程序，用于发射局部指示信号，例如来自LED的闪烁信号，如果检测器的电源和接地端子以正确的方向（即极性）连接到电源 和电源的接地线。 通过这种方式，安装危险检测器的人员可以在连接后立即告知检测器是否以正确的方向连接，并避免引入诸如热或烟的危险，以测试检测器的操作。 变化使用更复杂的程序，在测试模式期间禁用检测器阻止伪报警信号的复杂过滤算法; 如果这种过滤不被禁用，则阻碍检测器的正常测试。

    Infra-red flame detector
    5.
    发明授权
    Infra-red flame detector 失效
    红外线火焰探测器

    公开(公告)号：US4471221A

    公开(公告)日：1984-09-11

    申请号：US369083

    申请日：1982-04-16

    申请人： John F. Middleton ,  Roger Barrett ,  Terence A. Garrett

    发明人： John F. Middleton ,  Roger Barrett ,  Terence A. Garrett

    IPC分类号： G01J1/42 ,  F23M11/04 ,  F23N5/08 ,  G01J5/60 ,  G08B17/12 ,  G01J1/00

    CPC分类号： G08B17/12 ,  G01J5/60

    摘要： A flame detector arranged to detect flames includes a non-microphonic infra-red sensor having a broad band frequency response. To maximize the sensitivity to radiation from flames in the 4.3 .mu.m solar absorption band a narrow band optical interference filer, transmissive in the band 4.54 .mu.m to 4.38 .mu.m is chosen such that the integrated solar energy transmitted thereby is less than an alarm threshold.A further filter prevents re-radiated heat from the filter reaching the sensor. Another filter prevents radiation of wavelengths less than 4.38 .mu.m from reaching the other filters to reduce heating thereof and also to provide a series of filters to stop direct broad band transmission to the sensor through pin holes in the filters. A signal processor detects flames by virtue of the flame flicker frequencies and includes provision for compensating for the effects of low frequency components on the amplitude of radiation produced by flames.

    摘要翻译： 布置成检测火焰的火焰检测器包括具有宽带频率响应的非麦克风红外传感器。 为了最大限度地提高对4.3μm太阳能吸收带中火焰辐射的敏感度，选择在4.54μm至4.38μm的频带内透射的窄带光学干涉滤光片，使得由此传输的积分太阳能小于报警阈值 。 进一步的过滤器防止过滤器的再辐射热到达传感器。 另一个过滤器防止波长小于4.38微米的辐射到达其他过滤器以减少其加热，并且还提供一系列过滤器，以通过过滤器中的针孔阻止对传感器的直接宽带传输。 信号处理器通过火焰闪烁频率来检测火焰，并且包括补偿低频分量对由火焰产生的辐射振幅的影响。

    Hazard detector
    6.
    发明授权
    Hazard detector 有权
    危险检测仪

    公开(公告)号：US07427925B2

    公开(公告)日：2008-09-23

    申请号：US10541434

    申请日：2004-01-05

    申请人： Roger Barrett ,  Jeffrey John Cutler

    发明人： Roger Barrett ,  Jeffrey John Cutler

    IPC分类号： G08B17/10

    CPC分类号： G08B29/24 ,  G08B29/145

    摘要： A hazard detector has an electronic circuit with a start-up program for causing emission of a local indicator signal, such as a flashing signal from a LED, if power and ground terminals of the detector are connected with proper orientation, i.e. polarity, to power and ground lines of a power supply. Through this means, a person installing the hazard detector can tell immediately after connection if the detector has been connected with proper orientation, and avoids the need for introducing a hazard such as heat or smoke to test the operation of the detector. A variation uses a more sophisticated program that disables, during a test mode, complex filtering algorithms that are used by detectors to block false alarm signals; if such filtering is not disabled, impedes normal testing of the detectors.

    摘要翻译： 危险检测器具有电子电路，其具有启动程序，用于发射局部指示信号，例如来自LED的闪烁信号，如果检测器的电源和接地端子以正确的方向（即极性）连接到电源 和电源的接地线。 通过这种方式，安装危险检测器的人员可以在连接后立即告知检测器是否以正确的方向连接，并避免引入诸如热或烟的危险，以测试检测器的操作。 变化使用更复杂的程序，在测试模式期间禁用检测器阻止伪报警信号的复杂过滤算法; 如果这种过滤不被禁用，则阻碍检测器的正常测试。