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公开(公告)号：US20050030605A1
公开(公告)日：2005-02-10
申请号：US10801319
申请日：2004-03-16
申请人： Roger Cannon , Timothy Green , Martin Klement , Daniel Pawley , Wilson Routt
发明人： Roger Cannon , Timothy Green , Martin Klement , Daniel Pawley , Wilson Routt
CPC分类号： G02B26/0833 , G02B26/085 , G02B26/105
摘要： An image scanning apparatus and a torsion oscillator are capable of operating across a dynamic range of possible operating frequencies. The image scanning apparatus uses a light source to produce a light beam, and the oscillator scans the light beam through a scanning pattern. The oscillator includes a plate member having a non-rectangular shape. At least one magnet is disposed on the plate. A surface of the plate member includes a reflective surface for reflecting a light beam. A frame is disposed in a spaced apart relation to a lower surface of the plate member. The frame includes at least one coil configured to induce an electromagnetic force on the at least one magnet to thereby oscillate the reflective surface to a rotational angle of oscillation at an oscillation frequency. The system also includes an imaging surface disposed in the path of the scanning pattern so that the light beam scans across the imaging surface, and a mechanical drive to move the imaging surface. A control system controls electric current provided to the at least one coil to achieve the oscillation.
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公开(公告)号：US20050013010A1
公开(公告)日：2005-01-20
申请号：US10915837
申请日：2004-08-11
申请人： Roger Cannon , Dana Dodds , Philip Heink , Robert Paterson , Daniel Pawley , Wilson Routt
发明人： Roger Cannon , Dana Dodds , Philip Heink , Robert Paterson , Daniel Pawley , Wilson Routt
CPC分类号： G02B3/02
摘要： A lens has a lens body (1), reinforcing extensions (3a, 3b) and a clear aperture (9) surrounded on top and bottom by lens body. The lens is suitable for spot scanning. The lens is made of a water absorbing material, such as most polymers, particularly acrylate polymers. Aluminum sheets as vapor barriers are attached on each side of the lens body. This results in excellent resistance to change or distortion in high humidity environments.
摘要翻译： 透镜具有透镜体（1），加强延伸部（3a，3b）和透明孔（9），透镜体在顶部和底部包围。 镜头适用于点扫。 透镜由吸水材料制成，例如大多数聚合物，特别是丙烯酸酯聚合物。 作为蒸气阻挡层的铝片被附着在透镜体的每一侧上。 这导致在高湿度环境下优异的抗变化或变形性。
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公开(公告)号：US20050134143A1
公开(公告)日：2005-06-23
申请号：US11034168
申请日：2005-01-12
申请人： Roger Cannon , Wilson Routt
发明人： Roger Cannon , Wilson Routt
CPC分类号： G02B26/105
摘要： An optical apparatus compensates for imaging errors associated with the sinusoidal angular scan rate of a light beam reflected from a bidirectional scanning torsion oscillator. The compensation is achieved by a combination of pre-scan optics positioned between the source of the light beam and the scanning torsion oscillator, and post-scan optics positioned between the scanning torsion oscillator and an imaging surface of an imaging device. Based on the optical characteristics of its components, the post-scan optical system causes deflection of the light beam in the scan direction. To compensate for the sinusoidal scan rate, the deflection caused by the post-scan optical system is greater at the opposing edge positions of the imaging surface than at a central position. In this manner, the scan rate of the light beam at the first and second edge positions is substantially equivalent to the scan rate at the central position. The pre-scan optical system directs the light beam onto the reflective surface of the torsion oscillator in a manner that compensates for divergence of the light beam in the scan direction caused by the post-scan optical system.
摘要翻译： 光学装置补偿与从双向扫描扭转振荡器反射的光束的正弦角扫描速率相关联的成像误差。 补偿通过位于光束源和扫描扭转振荡器之间的预扫描光学器件和位于扫描扭转振荡器和成像装置的成像表面之间的后扫描光学器件的组合来实现。 基于其组件的光学特性，后扫描光学系统导致光束在扫描方向上的偏转。 为了补偿正弦扫描速率，由扫描后光学系统引起的偏转在成像表面的相对边缘位置处比在中心位置处更大。 以这种方式，第一和第二边缘位置处的光束的扫描速率基本上等于在中心位置处的扫描速率。 预扫描光学系统以补偿由扫描后光学系统引起的扫描方向上的光束发散的方式将光束引导到扭转振荡器的反射表面上。
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公开(公告)号：US20050245796A1
公开(公告)日：2005-11-03
申请号：US11177015
申请日：2005-07-07
申请人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
发明人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
CPC分类号： A61B5/1455 , A61B3/10 , A61B5/14532 , A61B5/6821
摘要： An apparatus carries out measurements of blood glucose in a repeatable, non-invasive manner by measurement of the rate of regeneration of retinal visual pigments, such as cone visual pigments. The rate of regeneration of visual pigments is dependent upon the blood glucose concentration, and by measuring the visual pigment regeneration rate, blood glucose concentration can be accurately determined. This apparatus exposes the retina to light of selected wavelengths in selected distributions and subsequently analyzes the reflection (as color or darkness) from a selected portion of the exposed region of the retina, preferably from the fovea.
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公开(公告)号：US20050267343A1
公开(公告)日：2005-12-01
申请号：US11176986
申请日：2005-07-07
申请人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
发明人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
CPC分类号： A61B5/1455 , A61B3/10 , A61B5/14532 , A61B5/6821
摘要： An apparatus carries out measurements of blood glucose in a repeatable, non-invasive manner by measurement of the rate of regeneration of retinal visual pigments, such as cone visual pigments. The rate of regeneration of visual pigments is dependent upon the blood glucose concentration, and by measuring the visual pigment regeneration rate, blood glucose concentration can be accurately determined. This apparatus exposes the retina to light of selected wavelengths in selected distributions and subsequently analyzes the reflection (as color or darkness) from a selected portion of the exposed region of the retina, preferably from the fovea.
摘要翻译： 设备通过测量视网膜视觉颜料如锥形视觉颜料的再生速率，以可重复的非侵入性方式进行血糖测量。 视觉色素的再生速度取决于血糖浓度，通过测定视觉色素再生率，可以准确测定血糖浓度。 该设备将视网膜暴露于所选择的分布中所选择的波长的光，并随后分析来自视网膜的曝光区域的选定部分（优选为中央凹）的反射（作为颜色或黑暗）。
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公开(公告)号：US20050010091A1
公开(公告)日：2005-01-13
申请号：US10863619
申请日：2004-06-08
申请人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
发明人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
CPC分类号： A61B5/1455 , A61B3/10 , A61B5/14532 , A61B5/6821
摘要： An apparatus carries out measurements of blood glucose in a repeatable, non-invasive manner by measurement of the rate of regeneration of retinal visual pigments, such as cone visual pigments. The rate of regeneration of visual pigments is dependent upon the blood glucose concentration, and by measuring the visual pigment regeneration rate, blood glucose concentration can be accurately determined. This apparatus exposes the retina to light of selected wavelengths in selected distributions and subsequently analyzes the reflection (as color or darkness) from a selected portion of the exposed region of the retina, preferably from the fovea.
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公开(公告)号：US06650915B2
公开(公告)日：2003-11-18
申请号：US10012902
申请日：2001-10-22
申请人： Wilson Routt , Mark J. Rice
发明人： Wilson Routt , Mark J. Rice
IPC分类号： A61B500
CPC分类号： A61B5/1455 , A61B3/12 , A61B5/14532 , A61B5/14558
摘要： The determination of blood glucose in an individual is carried out by projecting illuminating light into an eye of the individual to illuminate the retina with the light having wavelengths that are absorbed by rhodopsin and with the intensity of the light varying in a prescribed temporal manner. The light reflected from the retina is detected to provide a signal corresponding to the intensity of the detected light, and the detected light signal is analyzed to determine the changes in form from that of the illuminating light. For a biased sinusoidal illumination, these changes can be expressed in terms of harmonic content of the detected light. The changes in form of the detected light are related to the ability of rhodopsin to absorb light and regenerate, which in turn is related to the concentration of blood glucose, allowing a determination of the relative concentration of blood glucose. Other photoreactive analytes can similarly be determined by projecting time varying illuminating light into the eye, detecting the light reflected from the retina, and analyzing the detected light signal to determine changes in form of the signal due to changes in absorptivity of a photoreactive analyte.
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公开(公告)号：US20060020184A1
公开(公告)日：2006-01-26
申请号：US11176995
申请日：2005-07-07
申请人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
发明人： Joe Woods , John Smith , Mark Rice , Wilson Routt , Robert Messerschmidt , Junli Ou
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B3/10 , A61B5/14532 , A61B5/6821
摘要： An apparatus carries out measurements of blood glucose in a repeatable, non-invasive manner by measurement of the rate of regeneration of retinal visual pigments, such as cone visual pigments. The rate of regeneration of visual pigments is dependent upon the blood glucose concentration, and by measuring the visual pigment regeneration rate, blood glucose concentration can be accurately determined. This apparatus exposes the retina to light of selected wavelengths in selected distributions and subsequently analyzes the reflection (as color or darkness) from a selected portion of the exposed region of the retina, preferably from the fovea.
摘要翻译： 设备通过测量视网膜视觉颜料如锥形视觉颜料的再生速率，以可重复的非侵入性方式进行血糖测量。 视觉色素的再生速度取决于血糖浓度，通过测定视觉色素再生率，可以准确测定血糖浓度。 该设备将视网膜暴露于所选择的分布中所选择的波长的光，并随后分析来自视网膜的曝光区域的选定部分（优选为中央凹）的反射（作为颜色或黑暗）。
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公开(公告)号：US06477394B2
公开(公告)日：2002-11-05
申请号：US09952491
申请日：2001-09-12
IPC分类号： A61B500
CPC分类号： A61B5/14532 , A61B3/1233 , A61B3/145 , A61B5/0013 , A61B5/14546 , A61B5/1455
摘要： Illuminating light of selected wavelengths in the visible or infrared range is projected through the pupil of the eye onto the fundus, and the light reflected back and out through the pupil is detected and analyzed, preferably using the area of the optic disk for analyzing the retinal vessels overlying the optic disk. Specific wavelengths of illuminating light may be chosen for each blood component to be analyzed depending on the spectral characteristics of the substance being analyzed. The reflected image from the retina may be used to measure non-photoreactive blood components such as hemoglobin, and photoreactive components such as bilirubin. For the measurement of photoreactive components, images may be taken before and after, or during, illumination of the eye with light at wavelengths which will affect the photoreactive analyte, enabling measurements of the concentration of the analyte.
摘要翻译： 可见光或红外范围内所选波长的照明光通过眼睛的瞳孔投射到眼底，并且通过瞳孔反射回来的光被检测和分析，优选地使用用于分析视网膜的视盘的区域 覆盖视盘的血管。 可以根据被分析物质的光谱特性，为要分析的每个血液成分选择照射光的特定波长。 来自视网膜的反射图像可以用于测量非光反应性血液成分如血红蛋白和光反应性成分如胆红素。 对于光反应性成分的测量，可以在影响光反应性分析物的波长处的光照射之前或之后拍摄图像，从而能够测量分析物的浓度。
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公开(公告)号：US20050187443A1
公开(公告)日：2005-08-25
申请号：US11117818
申请日：2005-04-29
申请人： Wilson Routt , Mark Rice
发明人： Wilson Routt , Mark Rice
CPC分类号： A61B5/1455 , A61B3/12 , A61B5/14532 , A61B5/14558
摘要： The determination of blood glucose in an individual is carried out by projecting illuminating light into an eye of the individual to illuminate the retina with the light having wavelengths that are absorbed by rhodopsin and with the intensity of the light varying in a prescribed temporal manner. The light reflected from the retina is detected to provide a signal corresponding to the intensity of the detected light, and the detected light signal is analyzed to determine the changes in form from that of the illuminating light. For a biased sinusoidal illumination, these changes can be expressed in terms of harmonic content of the detected light. The changes in form of the detected light are related to the ability of rhodopsin to absorb light and regenerate, which in turn is related to the concentration of blood glucose, allowing a determination of the relative concentration of blood glucose. Other photoreactive analytes can similarly be determined by projecting time varying illuminating light into the eye, detecting the light reflected from the retina, and analyzing the detected light signal to determine changes in form of the signal due to changes in absorptivity of a photoreactive analyte.
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