公开(公告)号：US20080086274A1

公开(公告)日：2008-04-10

申请号：US11836947

申请日：2007-08-10

申请人： Roger Chamberlain ,  Jeremy Buhler ,  Arpith Jacob ,  Joseph Lancaster ,  Brandon Harris

发明人： Roger Chamberlain ,  Jeremy Buhler ,  Arpith Jacob ,  Joseph Lancaster ,  Brandon Harris

IPC分类号： G06F19/00

CPC分类号： G16B30/00

摘要： Disclosed herein is a hardware implementation for performing sequence alignment that preferably deploys a seed generation stage, an ungapped extension stage, and at least a portion of a gapped extension stage as a data processing pipeline on at least one hardware logic device. Hardware circuits for the seed generation stage, the ungapped extension stage, and the gapped extension stage are individually disclosed. In a preferred embodiment, the pipeline is arranged for performing BLASTP sequence alignment searching. Also, in a preferred embodiment, the at least one hardware logic device comprises at least one reconfigurable logic device such as an FPGA.

摘要翻译： 本文公开的是用于执行序列比对的硬件实现，其优选地在至少一个硬件逻辑设备上部署种子生成级，无间隙扩展级以及有间隙扩展级的至少一部分作为数据处理流水线。 用于种子生成阶段，无间隙延伸阶段和间隙扩展阶段的硬件电路被单独公开。 在优选实施例中，流水线被布置用于执行BLASTP序列比对搜索。 此外，在优选实施例中，至少一个硬件逻辑器件包括至少一个可重新配置的逻辑器件，例如FPGA。

公开(公告)号：US20070067108A1

公开(公告)日：2007-03-22

申请号：US11359285

申请日：2006-02-22

申请人： Jeremy Buhler ,  Roger Chamberlain ,  Mark Franklin ,  Kwame Gyang ,  Arpith Jacob ,  Praveen Krishnamurthy ,  Joseph Lancaster

发明人： Jeremy Buhler ,  Roger Chamberlain ,  Mark Franklin ,  Kwame Gyang ,  Arpith Jacob ,  Praveen Krishnamurthy ,  Joseph Lancaster

IPC分类号： G06F19/00

CPC分类号： G06F19/28 ,  G06F17/3033 ,  G06F19/22

摘要： A system and method for performing biological sequence similarity searching is disclosed. This includes a programmable logic device configured to include a pipeline that comprises a matching stage, the matching stage being configured to receive a data stream comprising a plurality of possible matches between a plurality of biological sequence data strings and a plurality of substrings of a query string. The pipeline may further include a ungapped extension prefilter stage located downstream from the matching stage, the prefilter stage being configured to shift through pattern matches between the biological sequence data strings and the plurality of substrings of a query string and provide a score so that only pattern matches that exceed a user defined score will pass downstream from the prefilter stage. The matching stage may include at least one Bloom filter.

摘要翻译： 公开了一种用于进行生物序列相似性搜索的系统和方法。 这包括被配置为包括包括匹配级的流水线的可编程逻辑设备，所述匹配级被配置为接收包括多个生物序列数据串与查询字符串的多个子串之间的多个可能匹配的数据流 。 流水线还可以包括位于匹配阶段下游的无间隙扩展预滤器级，预滤器级被配置为通过生物序列数据串与查询串的多个子串之间的模式匹配移位，并提供分数，使得只有模式 超过用户定义分数的匹配将从预过滤器阶段下游传递。 匹配阶段可以包括至少一个布隆过滤器。

公开(公告)号：US20210245021A1

公开(公告)日：2021-08-12

申请号：US16787745

申请日：2020-02-11

申请人： Joseph Lancaster

发明人： Joseph Lancaster

IPC分类号： A63B57/20 ,  A63B69/36

摘要： A golf tee holder includes a thin box having a top, a bottom and lateral open sides and a thickness based on a diameter of a golf tee. Laterally overlapping filaments (LOF) line the plurality of open sides and provide a friction retention of multiple golf tees inserted through the LOF into the thin box. Furthermore, a clip disposed on the thin box attaches it to a ball cap bill. A golf ball marker comprises a component of the thin box in some embodiments. A spring element within the thin box returns a golf tee pressed into it back out through the lateral overlapping filaments to a user of the thin box. The lateral overlapping filaments comprise one of bristles, fibers, cord, string, fuzz and tuft.

公开(公告)号：US5195297A

公开(公告)日：1993-03-23

申请号：US694075

申请日：1991-05-01

申请人： William G. Lancaster ,  Joseph Lancaster

发明人： William G. Lancaster ,  Joseph Lancaster

IPC分类号： B65B11/04

CPC分类号： B65B11/006 ,  B65B11/045

摘要： A load of successive units stacked in a longitudinal direction has aides with junctions extending in a lateral direction between successive units. Each of the units has at least one relatively high strength area which is resistant to circumferential crushing in the lateral direction and at least one low strength area which is substantially less resistant to circumferential crushing in the lateral direction than the high strength area. A film web is dispensed from a film web dispenser and stretched along the direction in which it is dispensed. The film web collapsed into a roped configuration and successively aligned with and within selected high strength areas by moving the film web dispenser generally in the lingitudinal direction relative to the load and stopping the relatively longitudinal movement of the web dispenser and the load at times when the web is in alignment with one of the selected high strength areas. The roped web is wrapped around the load at each of the selected high strength areas in alignment with each of the selected high strength areas. The web is then expanded from the roped configuration and wrapped around the load to cover the sides of the load in both the high and low strength areas.

摘要翻译： 在纵向方向堆叠的连续单元的负载具有在连续单元之间沿横向方向延伸的结的助剂。 每个单元具有至少一个相对高的强度区域，其耐横向方向的圆周破碎和至少一个低强度区域，其在横向方向上比在高强度区域上的周向破碎实质上更小。 薄膜网从薄膜卷筒纸分配器分配并沿其分配方向拉伸。 薄膜网络通过相对于负载在垂直方向上移动薄膜卷筒纸分配器并且连续地对齐并且在所选择的高强度区域内并且连续地对齐并且在相当长的方向上停止卷筒纸分配器和负载的相对纵向运动。 网格与选定的高强度区域之一保持一致。 在选定的高强度区域中的每个选择的高强度区域上，将卷绕的纤维网缠绕在负载下。 然后将网状物从拉丝构造扩展并且缠绕在负载上以覆盖高强度区域和低强度区域中的负载的侧面。