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公开(公告)号：US08369928B2
公开(公告)日：2013-02-05
申请号：US12564635
申请日：2009-09-22
IPC分类号： A61B5/05
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/5247
摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
摘要翻译： 描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。 实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。 双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。 在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。
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公开(公告)号：US20100076300A1
公开(公告)日：2010-03-25
申请号：US12564635
申请日：2009-09-22
IPC分类号： A61B5/055
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/5247
摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
摘要翻译： 描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。 实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。 双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。 在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。
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公开(公告)号：US08969816B2
公开(公告)日：2015-03-03
申请号：US13186891
申请日：2011-07-20
申请人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
发明人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： A printed circuit board (PCB) assembly of a data processing unit for an integrated magnetic resonance (MR) and positron emission tomography (PET) system, the PCB assembly includes a plurality of PCB layers disposed in a stacked arrangement, first and second PET signal processing circuits carried by a first layer of the plurality of PCB layers, first and second ground plane structures carried by a second layer of the plurality of PCB layers and configured relative to the first and second PET signal processing circuits, respectively, and a ground partition that separates the first PET signal processing circuit from the second PET signal processing circuit on the first layer. The ground partition extends through the first layer to provide electromagnetic interference (EMI) shielding between the first and second PET signal processing circuits.
摘要翻译： 一种用于集成磁共振（MR）和正电子发射断层摄影（PET）系统的数据处理单元的印刷电路板（PCB）组件，PCB组件包括以堆叠布置设置的多个PCB层，第一和第二PET信号 由多个PCB层的第一层承载的处理电路，由多个PCB层的第二层承载并分别相对于第一和第二PET信号处理电路配置的第一和第二接地平面结构以及接地分区 其将第一PET信号处理电路与第一PET信号处理电路分离在第一层上。 接地分隔件延伸穿过第一层，以在第一和第二PET信号处理电路之间提供电磁干扰（EMI）屏蔽。
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公开(公告)号：US08921796B1
公开(公告)日：2014-12-30
申请号：US14010953
申请日：2013-08-27
CPC分类号： G01T1/2985 , G01T1/171
摘要： A positron emission tomography (PET) system includes a PET detector configured to generate energy signals indicative of a set of events at the PET detector, a first discriminator coupled to the PET detector and configured to generate a primary timing signal in response to a primary event of the set of events, a second, derivative-based discriminator coupled to the PET detector and configured to generate a pileup timing signal in response to a piled-up event of the set of events, and a logic circuit to gate the primary and pileup timing signals of the first and second discriminators.
摘要翻译： 正电子发射断层摄影（PET）系统包括PET检测器，其被配置为产生指示PET检测器处的一组事件的能量信号;耦合到PET检测器的第一鉴别器，并且被配置为响应于主要事件产生主定时信号 的一组事件，第二个基于导数的鉴别器，耦合到PET检测器并且被配置为响应于该事件集合的堆叠事件产生堆积定时信号，以及逻辑电路，用于对初级和堆积 第一和第二鉴别器的定时信号。
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公开(公告)号：US08378306B2
公开(公告)日：2013-02-19
申请号：US13186950
申请日：2011-07-20
IPC分类号： G01T1/10
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： PET signals are amplified in a hybrid PET/MR system. An amplifier structure is provided for operation in the magnetic field of the MR magnets. By filtering to remove signals at the MR frequency (e.g., about 123 MHz) as part of the amplification circuit, the amplification circuit may be positioned within the RF cabin, within the magnetic field, and even within a same housing as the MR magnets. MR interference may be reduced by staged amplification. The filtering may be bi-directional, such as using parallel and series traps. Digitization of the PET signals may be provided within the magnetic field with no or little interference with MR operation.
摘要翻译： PET信号在混合PET / MR系统中被放大。 提供了用于在MR磁体的磁场中操作的放大器结构。 通过滤波以除去作为放大电路的一部分的MR频率（例如，约123MHz）的信号，放大电路可以位于RF舱内，在磁场内，甚至在与MR磁体相同的外壳内。 可以通过分阶段放大来减少MR干扰。 滤波可以是双向的，例如使用并联和串联阱。 可以在磁场内提供PET信号的数字化，没有或几乎没有MR操作的干扰。
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公开(公告)号：US20120022364A1
公开(公告)日：2012-01-26
申请号：US13186891
申请日：2011-07-20
申请人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
发明人： James Frank Caruba , Patanit Sanpitak , Grant Arthur Albert , Darryl Hrdina , Roger E. Arseneau , John P. Valenta
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： A printed circuit board (PCB) assembly of a data processing unit for an integrated magnetic resonance (MR) and positron emission tomography (PET) system, the PCB assembly includes a plurality of PCB layers disposed in a stacked arrangement, first and second PET signal processing circuits carried by a first layer of the plurality of PCB layers, first and second ground plane structures carried by a second layer of the plurality of PCB layers and configured relative to the first and second PET signal processing circuits, respectively, and a ground partition that separates the first PET signal processing circuit from the second PET signal processing circuit on the first layer. The ground partition extends through the first layer to provide electromagnetic interference (EMI) shielding between the first and second PET signal processing circuits.
摘要翻译： 一种用于集成磁共振（MR）和正电子发射断层摄影（PET）系统的数据处理单元的印刷电路板（PCB）组件，PCB组件包括以堆叠布置设置的多个PCB层，第一和第二PET信号 由多个PCB层的第一层承载的处理电路，由多个PCB层的第二层承载并分别相对于第一和第二PET信号处理电路配置的第一和第二接地平面结构以及接地分区 其将第一PET信号处理电路与第一PET信号处理电路分离在第一层上。 接地分隔件延伸穿过第一层，以在第一和第二PET信号处理电路之间提供电磁干扰（EMI）屏蔽。
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7.发明授权Methods and apparatus for protecting against X-ray infiltration in a SPECT scanner 有权用于在SPECT扫描仪中防止X射线渗透的方法和装置公开(公告)号：US07323691B1
公开(公告)日：2008-01-29
申请号：US11519411
申请日：2006-09-12
IPC分类号： G01T1/16
CPC分类号： G01T1/1615
摘要： Methods and apparatus provide for determining whether X-rays produced by a computer tomography (CT) scanner have infiltrated a single photon emission computed tomography (SPECT) scanner and shutting down at least one of a power source to one or more photo-multiplier tubes (PMTs) of the SPECT scanner, and an X-ray source of the CT scanner, when the determination is affirmative.
摘要翻译： 方法和装置提供用于确定由计算机断层摄影（CT）扫描仪产生的X射线是否渗透了单个光子发射计算机断层摄影（SPECT）扫描器并且将至少一个电源关闭到一个或多个光电倍增管（ PMT）和CT扫描仪的X射线源，当确定是肯定的。
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公开(公告)号：US20120018643A1
公开(公告)日：2012-01-26
申请号：US13186950
申请日：2011-07-20
CPC分类号： G01R33/28 , A61B5/055 , A61B6/037 , A61B6/5235 , G01R33/481 , Y10T307/305
摘要： PET signals are amplified in a hybrid PET/MR system. An amplifier structure is provided for operation in the magnetic field of the MR magnets. By filtering to remove signals at the MR frequency (e.g., about 123 MHz) as part of the amplification circuit, the amplification circuit may be positioned within the RF cabin, within the magnetic field, and even within a same housing as the MR magnets. MR interference may be reduced by staged amplification. The filtering may be bi-directional, such as using parallel and series traps. Digitization of the PET signals may be provided within the magnetic field with no or little interference with MR operation.
摘要翻译： PET信号在混合PET / MR系统中被放大。 提供了用于在MR磁体的磁场中操作的放大器结构。 通过滤波以除去作为放大电路的一部分的MR频率（例如，约123MHz）的信号，放大电路可以位于RF舱内，在磁场内，甚至在与MR磁体相同的外壳内。 可以通过分阶段放大来减少MR干扰。 滤波可以是双向的，例如使用并联和串联阱。 可以在磁场内提供PET信号的数字化，而对MR操作没有或几乎没有干扰。
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公开(公告)号：US20130062525A1
公开(公告)日：2013-03-14
申请号：US13229797
申请日：2011-09-12
申请人： James Frank Caruba , Niraj K. Doshi , John W. Young , Nan Zhang
发明人： James Frank Caruba , Niraj K. Doshi , John W. Young , Nan Zhang
CPC分类号： G01T1/1648
摘要： Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control.
摘要翻译： 使用标准或现货电缆在PET块检测器和检测器电路之间进行互连可以节省大量成本，因为PET系统中PMT的数量。 鉴于空间限制，需要简单的维护，减少干扰布线的风险，不断增加布线需求，不断使用标准布线。 为了实现数字增益控制，在PET检测器块和检测器电路之间提供进一步的通信。 由于标准电缆可能没有用于这种通信的附加电线并且减少定时劣化，所以组合PMT信号，例如在PET检测器块处产生位置和能量信号。 四个PMT信号减少到三个信号，而不会降低功能，允许CAT5电缆中的第四根双绞线用于数字增益控制。
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公开(公告)号：US08735836B2
公开(公告)日：2014-05-27
申请号：US13229797
申请日：2011-09-12
申请人： James Frank Caruba , Niraj K Doshi , John W Young , Nan Zhang
发明人： James Frank Caruba , Niraj K Doshi , John W Young , Nan Zhang
IPC分类号： G01T1/164
CPC分类号： G01T1/1648
摘要： Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control.
摘要翻译： 使用标准或“现成”电缆在PET块检测器和检测器电路之间进行互连可以节省大量成本，因为PET系统中PMT的数量。 鉴于空间限制，需要简单的维护，减少干扰布线的风险，不断增加布线需求，不断使用标准布线。 为了实现数字增益控制，在PET检测器块和检测器电路之间提供进一步的通信。 由于标准电缆可能没有用于这种通信的附加电线并且减少定时劣化，所以组合PMT信号，例如在PET检测器块处产生位置和能量信号。 四个PMT信号减少到三个信号而不减少功能，允许CAT5电缆中的第四根双绞线用于数字增益控制。
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