Faims apparatus and method using carrier gases that contain a trace amount of a dopant species
    1.
    发明申请
    Faims apparatus and method using carrier gases that contain a trace amount of a dopant species 有权
    Faims装置和方法,其使用含有微量掺杂物质的载气

    公开(公告)号:US20050161596A1

    公开(公告)日:2005-07-28

    申请号:US10503713

    申请日:2003-02-07

    IPC分类号: G01N27/64 H01J49/04 H01J49/28

    CPC分类号: G01N27/624 H01J49/04

    摘要: Disclosed is a method and apparatus for improving at least one of a peak separation and a signal intensity relating to an ion of interest being transmitted through an analyzer region of a FAIMS apparatus. A method according to the instant invention includes a step of introducing ions including an ion of interest into an analyzer region of a FAIMS. A flow of a doped carrier gas other than air is also provided through the analyzer region. The doped carrier gas includes a carrier gas and a trace amount of a predetermined dopant gas, the predetermined dopant gas selected for improving at least one of a peak separation and a signal intensity relating to the ion of interest relative to the peak separation and the signal intensity relating to the ion of interest in the presence of the carrier gas only. The ion of interest is selectively transmitted through the analyzer region in the presence of the doped carrier gas, and detected at a detector.

    摘要翻译: 公开了一种用于改善通过FAIMS装置的分析器区域传输的与感兴趣的离子相关的峰值分离和信号强度中的至少一个的方法和装置。 根据本发明的方法包括将包含感兴趣的离子的离子引入到FAIMS的分析器区域中的步骤。 除了空气之外的掺杂载气的流动也通过分析器区域提供。 掺杂的载气包括载气和痕量的预定掺杂气体,所选择的预定掺杂剂气体相对于峰值分离和信号来改善峰值分离和与感兴趣的离子相关的信号强度中的至少一个 仅在载气存在下与感兴趣的离子有关的强度。 感兴趣的离子在掺杂的载气的存在下选择性地透过分析器区域,并在检测器处检测。

    FAIMS apparatus and method using carrier gases that contain a trace amount of a dopant species
    2.
    发明授权
    FAIMS apparatus and method using carrier gases that contain a trace amount of a dopant species 有权
    使用含有微量掺杂剂种类的载气的FAIMS装置和方法

    公开(公告)号:US07026612B2

    公开(公告)日:2006-04-11

    申请号:US10503713

    申请日:2003-02-07

    IPC分类号: H01J49/40

    CPC分类号: G01N27/624 H01J49/04

    摘要: Disclosed is a method and apparatus for improving at least one of a peak separation and a signal intensity relating to an ion of interest being transmitted through an analyzer region of a FAIMS apparatus. A method according to the instant invention includes a step of introducing ions including an ion of interest into an analyzer region of a FAIMS. A flow of a doped carrier gas other than air is also provided through the analyzer region. The doped carrier gas includes a carrier gas and a trace amount of a predetermined dopant gas, the predetermined dopant gas selected for improving at least one of a peak separation and a signal intensity relating to the ion of interest relative to the peak separation and the signal intensity relating to the ion of interest in the presence of the carrier gas only. The ion of interest is selectively transmitted through the analyzer region in the presence of the doped carrier gas, and detected at a detector.

    摘要翻译: 公开了一种用于改善通过FAIMS装置的分析器区域传输的与感兴趣的离子相关的峰值分离和信号强度中的至少一个的方法和装置。 根据本发明的方法包括将包含感兴趣的离子的离子引入到FAIMS的分析器区域中的步骤。 除了空气之外的掺杂载气的流动也通过分析器区域提供。 掺杂的载气包括载气和痕量的预定掺杂气体,所选择的预定掺杂剂气体相对于峰值分离和信号来改善峰值分离和与感兴趣的离子相关的信号强度中的至少一个 仅在载气存在下与感兴趣的离子有关的强度。 感兴趣的离子在掺杂的载气的存在下选择性地透过分析器区域,并在检测器处检测。