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公开(公告)号：US20220273910A1
公开(公告)日：2022-09-01
申请号：US17748105
申请日：2022-05-19
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
摘要： A pump for inducing negative pressure in the ureter and/or kidney is provided. The pump is configured to be in communication with at least one lumen of at least one ureteral catheter and to draw fluid from the ureter and/or kidney into the at least one lumen of the at least one ureteral catheter for removal of the fluid from the ureter and/or kidney. The pump is configured to induce negative pressure ranging from about 0.1 mmHg to about 50 mmHg gauge pressure proximate to the pump inlet, and the pump is configured to have an accuracy of about 10 mmHg or less proximate to the pump inlet.
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公开(公告)号：US20220265914A1
公开(公告)日：2022-08-25
申请号：US17738089
申请日：2022-05-06
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , Michael Alan Fisher , Patrick William Strane , Lance Michael Black , David E. Orr
摘要： A negative pressure therapy system is provided for inducing negative pressure in a portion of a urinary tract, the system including: (a) at least one ureteral catheter configured to be positioned within a ureter and/or kidney; (b) one or more sensor(s) configured to determine information about at least one of blood composition, blood flow, respiration, heart rate, glucose, protein, or creatinine; and (c) a controller configured to increase urine production by adjusting one or more operating parameters of a negative pressure source for inducing negative pressure through the at least one ureteral catheter into the urinary tract, based at least in part upon the information determined by the one or more sensor(s).
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公开(公告)号：US11904121B2
公开(公告)日：2024-02-20
申请号：US17154004
申请日：2021-01-21
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
IPC分类号： A61M27/00 , A61M1/00 , A61M25/00 , A61M25/04 , A61M25/10 , A61M39/12 , A61M25/02 , A61F13/20 , A61F13/15
CPC分类号： A61M27/008 , A61M1/70 , A61M1/73 , A61M1/743 , A61M1/80 , A61M1/84 , A61M25/0017 , A61M25/0023 , A61M25/0026 , A61M25/04 , A61M25/10 , A61M25/1025 , A61M39/12 , A61F13/2002 , A61F2013/15146 , A61M25/0068 , A61M25/0074 , A61M2025/0213 , A61M2202/0496 , A61M2205/0266 , A61M2205/3303 , A61M2205/3368 , A61M2205/50 , A61M2205/52 , A61M2205/75 , A61M2210/1085 , A61M2210/1092 , A61M2210/1096 , A61M2230/20 , A61M2230/50 , A61M2230/65
摘要： A negative pressure therapy system is provided for inducing negative pressure in a portion of a urinary tract of a patient, the system including: (a) at least one ureteral catheter configured to be positioned within a ureter and/or kidney of a patient; (b) one or more sensor(s) configured to determine information about urine produced within a urinary tract of the patient; and (c) a controller configured to increase urine production of the patient by adjusting one or more operating parameters of a negative pressure source for inducing negative pressure through the at least one ureteral catheter into the urinary tract of the patient, based at least in part upon the information determined by the one or more sensor(s).
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公开(公告)号：US20230364322A1
公开(公告)日：2023-11-16
申请号：US18195483
申请日：2023-05-10
申请人： Roivios Limited
IPC分类号： A61M1/00 , A61M25/00 , A61M60/178 , A61M60/216
CPC分类号： A61M1/962 , A61M25/0017 , A61M25/005 , A61M1/73 , A61M60/178 , A61M60/216
摘要： A wearable garment for removing fluid from a urinary tract comprises a garment body configured to be worn by a patient; a pump provided on the garment body; and a reservoir provided on the garment body. The pump has a fluid inlet in fluid communication with a urinary catheter and a fluid outlet. The reservoir is provided in fluid communication with the outlet of the pump. The pump is configured to apply negative pressure to the urinary catheter to remove fluid from the urinary tract.
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5.发明授权公开(公告)号：US11478607B2
公开(公告)日：2022-10-25
申请号：US16542680
申请日：2019-08-16
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , David E. Orr , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
摘要： Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.
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公开(公告)号：US12076225B2
公开(公告)日：2024-09-03
申请号：US16826347
申请日：2020-03-23
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , David E. Orr , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
CPC分类号： A61F2/04 , A61M1/74 , A61M1/80 , A61M25/0017 , A61M25/007 , A61M25/04 , A61M25/10 , A61M27/008 , A61F2002/048 , A61F2220/0008 , A61F2230/0091 , A61M1/84 , A61M2205/3303 , A61M2205/3334 , A61M2210/1085 , A61M2210/1089
摘要： Ureteral or bladder catheters and systems are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion including an outer periphery or protective surface area which prevents mucosal tissue from occluding one or more protected drainage holes, ports, or perforations disposed within the outer periphery or protective surface area upon application of negative pressure through the catheter.
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公开(公告)号：US12023459B2
公开(公告)日：2024-07-02
申请号：US17392165
申请日：2021-08-02
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
IPC分类号： A61M27/00 , A61F13/15 , A61F13/20 , A61M1/00 , A61M25/00 , A61M25/02 , A61M25/04 , A61M25/10 , A61M39/12
CPC分类号： A61M27/008 , A61M1/70 , A61M1/73 , A61M1/743 , A61M1/80 , A61M1/84 , A61M25/0017 , A61M25/0023 , A61M25/0026 , A61M25/04 , A61M25/10 , A61M25/1025 , A61M39/12 , A61F2013/15146 , A61F13/2002 , A61M25/0068 , A61M25/0074 , A61M2025/0213 , A61M2202/0496 , A61M2205/0266 , A61M2205/3303 , A61M2205/3368 , A61M2205/50 , A61M2205/52 , A61M2205/75 , A61M2210/1085 , A61M2210/1092 , A61M2210/1096 , A61M2230/20 , A61M2230/50 , A61M2230/65
摘要： Negative pressure therapy systems are provided for increasing urine production, the negative pressure therapy system including: (a) a pump assembly, the pump assembly including: (i) a pump configured to provide negative pressure to a kidney, and (ii) a controller configured to regulate the negative pressure provided by the pump within a pressure range that facilitates increased urine production from the kidney.
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8.发明授权公开(公告)号：US11612714B2
公开(公告)日：2023-03-28
申请号：US16542680
申请日：2019-08-16
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , David E. Orr , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
摘要： Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.
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公开(公告)号：US11471583B2
公开(公告)日：2022-10-18
申请号：US16670249
申请日：2019-10-31
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , Michael Alan Fisher , Patrick William Strane , Lance Michael Black , David E. Orr
摘要： A method for removing excess fluid from a patient with hemodilution is provided. The method includes: deploying a urinary tract catheter into the patient such that flow of urine from the ureter and/or kidney is transported within a drainage lumen of the catheter; applying negative pressure to the ureter and/or kidney through the drainage lumen of the catheter to extract urine from the patient; periodically measuring a hematocrit value of the patient; and if the measured hematocrit value is greater than a predetermined threshold value, ceasing the application of the negative pressure to the ureter and/or kidney. A system for removing excess fluid from a patient with hemodilution including a ureteral catheter and a pump is also provided.
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10.发明授权公开(公告)号：US11433217B2
公开(公告)日：2022-09-06
申请号：US16542680
申请日：2019-08-16
申请人： Roivios Limited
发明人： John R. Erbey, II , Jacob L. Upperco , David E. Orr , Michael Alan Fisher , Patrick William Strane , Lance Michael Black
摘要： Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.
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