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公开(公告)号：US20070093814A1
公开(公告)日：2007-04-26
申请号：US11247451
申请日：2005-10-11
IPC分类号： A61F2/30
CPC分类号： A61B17/7026 , A61B17/7001 , A61B17/7004 , A61B17/701 , A61B17/7028 , A61B17/7029
摘要： An elongated member forming a spinal support rod is implantable adjacent the spine of a patient, and includes an axial span or spans for spanning respective spinal levels to promote efficacious spinal support/stabilization. As with conventional spinal support rods used in connection with lumbar fusion and other related procedures, the elongated member extends in an axial direction, and is substantially dimensionally stable, both radially and axially. The elongated member is further capable of bending, flexing, and/or deflecting laterally (e.g., along any and/or substantially all transverse directions) to an extent that preserves at least some spinal motion. Such elongated members can include axial spans that manifest a radially segmented geometry relative to the axial direction, include a sleeve and a series of structural members or a coil spring enclosed within the sleeve, and/or include a coil spring and a restraining element passing at least partially through the coil spring.
摘要翻译： 形成脊柱支撑杆的细长构件可植入邻近患者的脊柱，并且包括跨越相应脊柱水平的轴向跨度或跨度以促进有效的脊柱支撑/稳定。 与用于腰椎融合和其他相关过程的常规脊椎支撑杆一样，细长构件在轴向方向上延伸，并且在径向和轴向上都基本上尺寸稳定。 细长构件还能够横向（例如，沿着任何和/或基本上所有横向）弯曲，弯曲和/或偏转到保持至少一些脊柱运动的程度。 这种细长构件可以包括表现出相对于轴向方向的径向分段几何形状的轴向跨度，包括套筒和一系列结构构件或封闭在套筒内的螺旋弹簧，和/或包括螺旋弹簧和限制元件 最少部分地通过螺旋弹簧。
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公开(公告)号：US20070093813A1
公开(公告)日：2007-04-26
申请号：US11247450
申请日：2005-10-11
IPC分类号： A61F2/30
CPC分类号： A61B17/7004 , A61B17/7001 , A61B17/7023 , A61B17/7029 , A61B17/7031
摘要： An elongated member forming a spinal support rod is implantable adjacent the spine of a patient and includes an axial span or spans for spanning respective spinal levels to promote efficacious spinal support/stabilization. The axial span has an axially articulable geometry, and manifests an angulation mechanism along one or more transverse directions of at least seven degrees across a given spinal level. The angulation mechanism may be associated with joints between structural elements assembled in serial along the axial span, or via a common connection between such structural elements and a restraining element. Rotation between such structural elements can be global. The axial span may have a rod-like profile of a diameter similar to conventional spinal support rods used for lumbar spinal fusion, and provides for use across multiple spinal levels and with multiple adjustable attachment points for associated spine attachment devices to accommodate different patient anatomies.
摘要翻译： 形成脊柱支撑杆的细长构件可植入邻近患者的脊柱并且包括跨越相应脊柱水平的轴向跨度或跨度以促进有效的脊柱支撑/稳定。 轴向跨度具有轴向可铰接的几何形状，并且沿着给定脊柱水平的至少七度的一个或多个横向方向显示出角度机制。 角度调节机构可以与沿着轴向跨度串联组装的结构元件之间的接头相关联，或者通过这种结构元件和限制元件之间的公共连接。 这种结构元件之间的旋转可以是全局的。 轴向跨度可以具有类似于用于腰椎融合的常规脊柱支撑杆的直径的杆状轮廓，并且提供跨多个脊柱水平使用并且具有用于相关联的脊柱附接装置的多个可调节附接点以适应不同的患者解剖结构。
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公开(公告)号：US20070093815A1
公开(公告)日：2007-04-26
申请号：US11247860
申请日：2005-10-11
IPC分类号： A61F2/30
CPC分类号： A61B17/7029 , A61B17/7001 , A61B17/701 , A61B17/7026 , A61B17/7028
摘要： An elongated member forming a spinal support rod is implantable adjacent the spine of a patient and includes an axial span or spans for spanning respective spinal levels to promote efficacious spinal support/stabilization. The axial span manifests a double helical geometry. The axial span has a rod-like profile of a diameter similar to conventional spinal support rods used for lumbar spinal fusion, and provides for use across multiple spinal levels and with multiple adjustable attachment points for associated spine attachment devices, such as pedicle screws, to accommodate different patient anatomies.
摘要翻译： 形成脊柱支撑杆的细长构件可植入邻近患者的脊柱并且包括跨越相应脊柱水平的轴向跨度或跨度以促进有效的脊柱支撑/稳定。 轴向跨度表现出双螺旋几何形状。 轴向跨度具有类似于用于腰椎融合的常规脊柱支撑杆的直径的杆状轮廓，并且提供跨多个脊柱水平使用并且具有用于相关联的脊柱附接装置（例如椎弓根螺钉）的多个可调节附接点 适应不同的患者解剖。
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公开(公告)号：US20050177166A1
公开(公告)日：2005-08-11
申请号：US11027245
申请日：2004-12-31
申请人： Jens Timm , Bryan Hildebrand , Ronald Callahan , Ernest Corrao , Stephen MaGuire , Carmen Walters
发明人： Jens Timm , Bryan Hildebrand , Ronald Callahan , Ernest Corrao , Stephen MaGuire , Carmen Walters
CPC分类号： A61B17/7025 , A61B17/7004 , A61B17/7007 , A61B17/7011 , A61B17/7028 , A61B17/7035 , A61B17/7037 , A61B17/704 , A61B17/7041 , A61B17/705 , A61B17/7076 , A61B17/7083 , A61B17/8685 , A61B2017/00991
摘要： A pedicle screw is provided that includes an upwardly extending collet. The collet may include downwardly extending slots that define deflectable segments therebetween. When a spherical element or other structure, e.g., a non-dynamic stabilizing element, is positioned around the collet, introduction of a set screw causes outward deflection of the upstanding segments into engagement with the spherical element. A snap ring may be interposed between the collet and the spherical element to facilitate positioning therebetween. In an alternative embodiment, a non-slotted collet is employed. In such embodiment, the collet and the spherical element may be threadingly engaged and may include a snap ring therebetween. The pedicle screw subassemblies may be incorporated into a spinal stabilization system which may include a dynamic stabilizing member to provide clinically efficacious results.
摘要翻译： 提供了一种椎弓根螺钉，其包括向上延伸的夹头。 夹头可以包括向下延伸的槽，其在其间限定可偏转的段。 当球形元件或其它结构例如非动态稳定元件围绕夹头定位时，定位螺钉的引入导致直立段的向外偏转与球形元件接合。 卡扣环可以插入在夹头和球形元件之间以便于它们之间的定位。 在替代实施例中，采用非槽型夹头。 在这种实施例中，夹头和球形元件可以螺纹接合，并且可以在其间包括卡环。 椎弓根螺钉组件可以结合到脊柱稳定系统中，其可以包括动态稳定构件以提供临床上有效的结果。
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5.发明申请公开(公告)号：US20050182409A1
公开(公告)日：2005-08-18
申请号：US11027247
申请日：2004-12-31
申请人： Ronald Callahan , Jeffrey White , Ernest Corrao , Stephen Maguire
发明人： Ronald Callahan , Jeffrey White , Ernest Corrao , Stephen Maguire
CPC分类号： A61B17/7025 , A61B17/7004 , A61B17/7007 , A61B17/7011 , A61B17/7028 , A61B17/7035 , A61B17/7037 , A61B17/704 , A61B17/7041 , A61B17/705 , A61B17/7076 , A61B17/7083 , A61B17/8685 , A61B2017/00991
摘要： A motion interface structure for use with a pedicle screw is provided, the motion interface structure defining a central passage having an internal face. A helical thread is formed on at least a portion of the internal face of the central passage. The motion interface element is designed to cooperate with an upstanding region of a pedicle screw. The upstanding region includes a threaded region that is adapted to threadingly engage the helical thread associated with the motion interface element. The motion interface element may take the form of a spherical element or a universal joint mechanism. The pedicle screw and motion interface element may be incorporated into a spinal stabilization system that includes one or more additional pedicle screw/motion interface element subassemblies. The spinal stabilization system may also include a dynamic stabilizing element that provides clinically efficacious results.
摘要翻译： 提供了一种与椎弓根螺钉一起使用的运动界面结构，所述运动界面结构限定具有内表面的中心通道。 在中心通道的内表面的至少一部分上形成螺旋形螺纹。 运动界面元件被设计成与椎弓根螺钉的直立区域配合。 直立区域包括螺纹区域，其适于螺纹地接合与运动界面元件相关联的螺旋螺纹。 运动界面元件可以采取球形元件或万向节机构的形式。 椎弓根螺钉和运动界面元件可以结合到包括一个或多个另外的椎弓根螺钉/运动界面元件子组件的脊柱稳定系统中。 脊柱稳定系统还可以包括提供临床有效结果的动态稳定元件。
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公开(公告)号：US07615068B2
公开(公告)日：2009-11-10
申请号：US11027245
申请日：2004-12-31
申请人： Jens Peter Timm , Bryan Hildebrand , Ronald Callahan , Ernest Corrao , Stephen Maguire , Carmen Walters
发明人： Jens Peter Timm , Bryan Hildebrand , Ronald Callahan , Ernest Corrao , Stephen Maguire , Carmen Walters
CPC分类号： A61B17/7025 , A61B17/7004 , A61B17/7007 , A61B17/7011 , A61B17/7028 , A61B17/7035 , A61B17/7037 , A61B17/704 , A61B17/7041 , A61B17/705 , A61B17/7076 , A61B17/7083 , A61B17/8685 , A61B2017/00991
摘要： A pedicle screw is provided that includes an upwardly extending collet. The collet may include downwardly extending slots that define deflectable segments therebetween. When a spherical element or other structure, e.g., a non-dynamic stabilizing element, is positioned around the collet, introduction of a set screw causes outward deflection of the upstanding segments into engagement with the spherical element. A snap ring may be interposed between the collet and the spherical element to facilitate positioning therebetween. In an alternative embodiment, a non-slotted collet is employed. In such embodiment, the collet and the spherical element may be threadingly engaged and may include a snap ring therebetween. The pedicle screw subassemblies may be incorporated into a spinal stabilization system which may include a dynamic stabilizing member to provide clinically efficacious results.
摘要翻译： 提供了一种椎弓根螺钉，其包括向上延伸的夹头。 夹头可以包括向下延伸的槽，其在其间限定可偏转的段。 当球形元件或其它结构例如非动态稳定元件围绕夹头定位时，定位螺钉的引入导致直立段的向外偏转与球形元件接合。 卡扣环可以插入在夹头和球形元件之间以便于它们之间的定位。 在替代实施例中，采用非槽型夹头。 在这种实施例中，夹头和球形元件可以螺纹接合，并且可以在其间包括卡环。 椎弓根螺钉组件可以结合到脊柱稳定系统中，其可以包括动态稳定构件以提供临床上有效的结果。
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公开(公告)号：US07635379B2
公开(公告)日：2009-12-22
申请号：US11027247
申请日：2004-12-31
申请人： Ronald Callahan , Jeffrey White , Ernest Corrao , Stephen Maguire
发明人： Ronald Callahan , Jeffrey White , Ernest Corrao , Stephen Maguire
IPC分类号： A61B17/58
CPC分类号： A61B17/7025 , A61B17/7004 , A61B17/7007 , A61B17/7011 , A61B17/7028 , A61B17/7035 , A61B17/7037 , A61B17/704 , A61B17/7041 , A61B17/705 , A61B17/7076 , A61B17/7083 , A61B17/8685 , A61B2017/00991
摘要： A motion interface structure for use with a pedicle screw is provided, the motion interface structure defining a central passage having an internal face. A helical thread is formed on at least a portion of the internal face of the central passage. The motion interface element is designed to cooperate with an upstanding region of a pedicle screw. The upstanding region includes a threaded region that is adapted to threadingly engage the helical thread associated with the motion interface element. The motion interface element may take the form of a spherical element or a universal joint mechanism. The pedicle screw and motion interface element may be incorporated into a spinal stabilization system that includes one or more additional pedicle screw/motion interface element subassemblies. The spinal stabilization system may also include a dynamic stabilizing element that provides clinically efficacious results.
摘要翻译： 提供了一种与椎弓根螺钉一起使用的运动界面结构，所述运动界面结构限定具有内表面的中心通道。 在中心通道的内表面的至少一部分上形成螺旋形螺纹。 运动界面元件被设计成与椎弓根螺钉的直立区域配合。 直立区域包括螺纹区域，其适于螺纹地接合与运动界面元件相关联的螺旋螺纹。 运动界面元件可以采取球形元件或万向节机构的形式。 椎弓根螺钉和运动界面元件可以结合到包括一个或多个另外的椎弓根螺钉/运动界面元件子组件的脊柱稳定系统中。 脊柱稳定系统还可以包括提供临床有效结果的动态稳定元件。
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8.发明申请Pedicle screw devices, systems and methods having a preloaded set screw 审中-公开椎弓根螺钉装置，系统和方法具有预加载的固定螺钉公开(公告)号：US20050177164A1
公开(公告)日：2005-08-11
申请号：US11027082
申请日：2004-12-31
申请人： Carmen Walters , Bryan Hildebrand , Jens Timm , Ronald Callahan , Ernest Corrao , Stephen Maguire , Jeffrey White
发明人： Carmen Walters , Bryan Hildebrand , Jens Timm , Ronald Callahan , Ernest Corrao , Stephen Maguire , Jeffrey White
CPC分类号： A61B17/7025 , A61B17/7004 , A61B17/7007 , A61B17/7011 , A61B17/7028 , A61B17/7034 , A61B17/7035 , A61B17/7037 , A61B17/704 , A61B17/7041 , A61B17/705 , A61B17/7076 , A61B17/7083 , A61B17/8685 , A61B2017/00991
摘要： A pedicle screw assembly is provided that includes a pedicle screw and a preloaded set screw. The set screw is preloaded in a threaded, central aperture formed in the head region of the pedicle screw. An interference is advantageously formed on the set screw to prevent dislodgement of the set screw, e.g., during shipment and/or clinical placement of the pedicle screw. An upwardly extending collet is generally formed in the head region of the pedicle screw, the collet being sized to receive a spherical element therearound. Advancement of the set screw relative to the pedicle screw secures the spherical element relative to the pedicle screw. The spherical element typically includes a socket member that cooperates with a dynamic stabilizing member. The pedicle screw assembly and dynamic stabilizing member are advantageously used as part of a spinal stabilization system to provide clinically efficacious results.
摘要翻译： 提供了一种椎弓根螺钉组件，其包括椎弓根螺钉和预加载的固定螺钉。 固定螺钉预先装载在形成在椎弓根螺钉的头部区域中的带螺纹的中心孔中。 有利地在固定螺钉上形成干涉，以防止例如在椎弓根螺钉的运输和/或临床放置期间固定螺钉的移位。 通常在椎弓根螺钉的头部区域中形成向上延伸的夹头，夹头的尺寸被设计成在其周围容纳球形元件。 固定螺钉相对于椎弓根螺钉的推进使球形元件相对于椎弓根螺钉固定。 球形元件通常包括与动态稳定构件协作的插座构件。 椎弓根螺钉组件和动态稳定构件有利地用作脊柱稳定系统的一部分，以提供临床上有效的结果。
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公开(公告)号：US5605672A
公开(公告)日：1997-02-25
申请号：US74319
申请日：1993-06-09
CPC分类号： A61K51/065
摘要： The invention features a method of blood pool imaging which utilizes an imaging agent which can be easily labelled with a radioactive isotope and injected into a patient. The imaging agent is a covalent conjugate of a polymeric carrier, protective groups, and chelating groups. The imaging agent is preferably provided in the form of a blood pool imaging composition, which includes an imaging agent of the invention, a buffer and a reducing compound. A radioactive isotope is added to the blood pool imaging composition to label the imaging agent, and the composition containing the labelled imaging agent is injected intravenously into a patient.
摘要翻译： 本发明的特征在于一种血液池成像方法，该方法利用能容易地用放射性同位素标记并注射到患者体内的成像剂。 显影剂是聚合物载体，保护基团和螯合基团的共价缀合物。 成像剂优选以血液成像组合物的形式提供，其包括本发明的显像剂，缓冲液和还原性化合物。 将放射性同位素添加到血液池成像组合物中以标记显影剂，并将含有标记的成像剂的组合物静脉内注射入患者体内。
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