专利检索 ap:("Ronald J. Biediger" OR "Michele A. Benish" OR "Lindsay Bonner Hardy" OR "Vincent A. Boyd" OR "Robert V. Market" OR "Thomas P. Thrash" OR "Brandon M. Young") AND inv:"Lindsay Bonner Hardy" 第 1 页

1.

发明申请
Propionic Acid Derivatives and Methods of Use Thereof 审中-公开

公开(公告)号：US20180312523A1

公开(公告)日：2018-11-01

申请号：US15497414

申请日：2017-04-26

申请人： Ronald J. Biediger , Michele A. Benish , Lindsay Bonner Hardy , Vincent A. Boyd , Robert V. Market , Thomas P. Thrash , Brandon M. Young

发明人： Ronald J. Biediger , Michele A. Benish , Lindsay Bonner Hardy , Vincent A. Boyd , Robert V. Market , Thomas P. Thrash , Brandon M. Young

IPC分类号： C07D498/04 , C07D213/75 , C07D213/64 , C07D207/327 , C07C69/618 , C07D307/54 , C07D401/12 , C07D221/18 , C07D207/333 , C07C313/06 , C07D333/22 , C07D231/16 , C07D471/04 , C07D261/08 , C07D213/55 , C07D213/48 , C07D213/69 , C07C47/575 , C07C47/55 , C07D209/08 , C07D237/14

摘要： Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.