公开(公告)号：US20060078892A1

公开(公告)日：2006-04-13

申请号：US10962670

申请日：2004-10-13

申请人： David Hammond ,  Ruben Carbonell ,  Honglue Shen ,  Patrick Gurgel ,  Viterose Wiltshire-Lyerly ,  Steven Burton

发明人： David Hammond ,  Ruben Carbonell ,  Honglue Shen ,  Patrick Gurgel ,  Viterose Wiltshire-Lyerly ,  Steven Burton

IPC分类号： C12Q1/68 ,  C12P21/06

CPC分类号： B01J20/286 ,  B01J20/265 ,  B01J20/285 ,  B01J20/321 ,  B01J20/3219 ,  B01J20/3246 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3257 ,  B01J20/3293 ,  B01J2220/54

摘要： Prion protein binding materials and methods for using the binding materials to detect or remove a prion protein from a sample, such as a biological fluid or an environmental sample. The binding materials are capable of binding to one or more forms of prion protein including cellular prion protein (PrPc), infectious prion protein (PrPsc), recombinant prion protein (PrPr), and proteinase resistant prion protein (PrPres). Prions from various species, including humans and hamsters, are bound by the binding materials.

公开(公告)号：US20050014196A1

公开(公告)日：2005-01-20

申请号：US10817117

申请日：2004-04-02

申请人： Ruben Carbonell ,  Honglue Shen ,  Patrick Gurgel ,  Viterose Wiltshire-Lyerly ,  David Hammond ,  Steven Burton

发明人： Ruben Carbonell ,  Honglue Shen ,  Patrick Gurgel ,  Viterose Wiltshire-Lyerly ,  David Hammond ,  Steven Burton

IPC分类号： C12N20060101 ,  G01N33/53 ,  G01N33/68

CPC分类号： G01N33/6896

摘要： Prion protein binding materials and methods for using the binding materials to detect or remove a prion protein from a sample, such as a biological fluid or an environmental sample. The binding materials are capable of binding to one or more forms of prion protein including cellular prion protein (PrPc), infectious prion protein (PrPsc), recombinant prion protein (PrPr), and proteinase resistant prion protein (PrPres). Prions from various species, including humans and hamsters, are bound by the binding materials.

摘要翻译： 朊病毒蛋白结合材料和使用结合材料从样品如生物流体或环境样品中检测或除去朊病毒蛋白的方法。 结合材料能够结合一种或多种形式的朊病毒蛋白，包括细胞朊蛋白（PrPc），感染性朊病毒蛋白（PrPsc），重组朊病毒蛋白（PrPr）和蛋白酶抗性朊病毒蛋白（PrPres）。 来自各种物种的朊病毒，包括人类和仓鼠，都受到结合物质的束缚。

公开(公告)号：US07510848B2

公开(公告)日：2009-03-31

申请号：US10962670

申请日：2004-10-13

申请人： David J. Hammond ,  Ruben G. Carbonell ,  Honglue Shen ,  Patrick V. Gurgel ,  Viterose Wiltshire-Lyerly ,  Steven J. Burton

发明人： David J. Hammond ,  Ruben G. Carbonell ,  Honglue Shen ,  Patrick V. Gurgel ,  Viterose Wiltshire-Lyerly ,  Steven J. Burton

IPC分类号： G01N33/53 ,  G01N33/68 ,  A61K39/00 ,  C12N15/00

CPC分类号： B01J20/286 ,  B01J20/265 ,  B01J20/285 ,  B01J20/321 ,  B01J20/3219 ,  B01J20/3246 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3257 ,  B01J20/3293 ,  B01J2220/54

摘要： Prion protein binding materials and methods for using the binding materials to detect or remove a prion protein from a sample, such as a biological fluid or an environmental sample. The binding materials are capable of binding to one or more forms of prion protein including cellular prion protein (PrPc), infectious prion protein (PrPsc), recombinant prion protein (PrPr), and proteinase resistant prion protein (PrPres). Prions from various species, including humans and hamsters, are bound by the binding materials.

摘要翻译： 朊病毒蛋白结合材料和使用结合材料从样品如生物流体或环境样品中检测或除去朊病毒蛋白的方法。 结合材料能够结合一种或多种形式的朊病毒蛋白，包括细胞朊蛋白（PrPc），感染性朊病毒蛋白（PrPsc），重组朊病毒蛋白（PrPr）和蛋白酶抗性朊病毒蛋白（PrPres）。 来自各种物种的朊病毒，包括人类和仓鼠，都受到结合物质的束缚。