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1.
公开(公告)号:US07312025B2
公开(公告)日:2007-12-25
申请号:US10618076
申请日:2003-07-11
申请人: Ryo Kubota , Thomas A Reh , Andrew J Fischer
发明人: Ryo Kubota , Thomas A Reh , Andrew J Fischer
CPC分类号: C12N5/0621 , C12N5/062 , C12N2502/08 , C12N2503/02
摘要: A cell culture system related to extended in vitro culture of mature neuronal cells and methods for preparing the cell culture system are provided. In a preferred embodiment the invention provides a cell culture system comprising a mixture of mature neuronal retinal cells and cells isolated from a ciliary body. Methods for identifying bioactive agents that alter neurodegeneration of neuronal retinal cells are also provided.
摘要翻译: 提供了与成熟神经元细胞的延长的体外培养相关的细胞培养系统和用于制备细胞培养系统的方法。 在优选的实施方案中,本发明提供了包含成熟神经元视网膜细胞和从睫状体分离的细胞的混合物的细胞培养系统。 还提供了用于鉴定改变神经元视网膜细胞的神经变性的生物活性剂的方法。