公开(公告)号：US10898470B1

公开(公告)日：2021-01-26

申请号：US16730731

申请日：2019-12-30

申请人： SATO PHARMACEUTICAL CO., LTD.

发明人： Masahiro Ito ,  Kiyotaka Matsui ,  Masami Inuma

IPC分类号： A61K31/4178 ,  A61K47/12 ,  A61K47/08 ,  A61K47/10 ,  A61P31/10 ,  A61K47/32 ,  A61K9/00 ,  A61K47/22

摘要： The present invention provides a technique that allows a pharmaceutical composition, preferably for external use, containing luliconazole or the like to contain luliconazole or the like at a high concentration, and suppresses the precipitation thereof over time. The present invention uses a polyethylene glycol having an average molecular weight of 380 to 420 represented by a formula HOCH2(CH2OCH2)nCH2OH (where n is an integer), ethanol, benzyl alcohol, lactic acid, propylene carbonate, and acetone in combination with the luliconazole or the like.

公开(公告)号：US11738006B2

公开(公告)日：2023-08-29

申请号：US17125591

申请日：2020-12-17

申请人： SATO PHARMACEUTICAL CO., LTD.

发明人： Masahiro Ito ,  Kiyotaka Matsui ,  Masami Inuma

IPC分类号： A61K31/4178 ,  A61K47/12 ,  A61K47/22 ,  A61K47/08 ,  A61K9/00 ,  A61P31/10 ,  A61K47/10 ,  A61K47/32

CPC分类号： A61K31/4178 ,  A61K9/0014 ,  A61K47/08 ,  A61K47/10 ,  A61K47/12 ,  A61K47/22 ,  A61K47/32 ,  A61P31/10

摘要： The present invention provides a technique that allows a pharmaceutical composition, preferably for external use, containing luliconazole or the like to contain luliconazole or the like at a high concentration, and suppresses the precipitation thereof over time. The present invention uses a polyethylene glycol having an average molecular weight of 380 to 420 represented by a formula HOCH2(CH2OCH2)nCH2OH (where n is an integer), ethanol, benzyl alcohol, lactic acid, propylene carbonate, and acetone in combination with the luliconazole or the like.

公开(公告)号：US20210220338A1

公开(公告)日：2021-07-22

申请号：US17125591

申请日：2020-12-17

申请人： SATO PHARMACEUTICAL CO., LTD.

发明人： Masahiro Ito ,  Kiyotaka Matsui ,  Masami Inuma

IPC分类号： A61K31/4178 ,  A61K47/10 ,  A61K47/12 ,  A61P31/10 ,  A61K47/08 ,  A61K47/32 ,  A61K9/00 ,  A61K47/22

摘要： The present invention provides a technique that allows a pharmaceutical composition, preferably for external use, containing luliconazole or the like to contain luliconazole or the like at a high concentration, and suppresses the precipitation thereof over time. The present invention uses a polyethylene glycol having an average molecular weight of 380 to 420 represented by a formula HOCH2(CH2OCH2)nCH2OH (where n is an integer), ethanol, benzyl alcohol, lactic acid, propylene carbonate, and acetone in combination with the luliconazole or the like.