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    N-substituted 4-aminosteroids
    1.
    发明授权
    N-substituted 4-aminosteroids 失效
    N-取代的4-氨基苯甲酸酯

    公开(公告)号：US3637668A

    公开(公告)日：1972-01-25

    申请号：US3637668D

    申请日：1969-02-27

    申请人： SCHERING AG

    发明人： LAURENT HENRY ,  STEINBECK HERMANN ,  WEICHERT RUDOLF

    IPC分类号： A61K31/57 ,  A61K31/573 ,  A61K31/58 ,  C07C173/00

    CPC分类号： A61K31/573 ,  A61K31/57 ,  A61K31/58

    摘要： 4-AMINOSTEROIDS OF THE PARTIAL FORMULA

    1-(R1-N(-R2)-),2-(O=)-2,3,3A,4-TETRAHYDROPENTALENE

    WHEREIN R1 AND R2 ARE ALKYL OR SUBSTITUTED ALKYL AND WHEREIN R1 AND R2 TOGETHER WITH THE NITROGEN WHICH IS ATTACHED IN THE 4-POSITION, MAY FORM AN ADDITIONAL RING AND WHEREIN SAID ADDITIONAL RING MAY INCLUDE A FURTHER HETERO ATOM OR A POSITIVE NITROGEN AND WHEREIN ST IS A STEROID MOLECULE RESIDUE. THE COMPOUNDS HAVE PARTICULAR USE AS PROGESTATIONAL AGENTS. THE COMPOUNDS OF THE ANDROSTANE SERIES HAVE ANDROGENOUS, ANABOLIC AND ANTIESTROGENIC PROPERTIES.