公开(公告)号：US20210278422A1

公开(公告)日：2021-09-09

申请号：US17256919

申请日：2019-09-05

Applicant: SEKISUI MEDICAL CO., LTD. ,  TOKUYAMA SEKISUI CO., LTD.

Inventor： Kazuyuki Oishi ,  Hiroaki Taira ,  Tomonori Inoue ,  Ryo Takemoto

IPC: G01N33/72 ,  G01N30/06 ,  G01N30/88

Abstract: Provided is a reagent for measuring hemoglobins capable of satisfactorily causing hemolysis and measuring hemoglobins with high accuracy. The reagent for measuring hemoglobins according to the present invention is a reagent for measuring hemoglobins used for measuring hemoglobins by cation exchange liquid chromatography, including a specific nonionic surfactant or a specific amphoteric surfactant.

公开(公告)号：US11221325B2

公开(公告)日：2022-01-11

申请号：US15025458

申请日：2014-09-30

Applicant: SEKISUI MEDICAL CO., LTD.

Inventor： Ryusuke Okamoto ,  Tomonori Inoue

IPC: G01N33/50 ,  G01N1/40 ,  G01N33/49 ,  G01N33/574

Abstract: To provide a device for concentration and separation of circulating tumor cells, capable of recovering circulating tumor cells in a blood-derived specimen simply, at a high recovery rate, and with low invasion of the tumor cells. A device for concentration and separation of circulating tumor cells present in a blood-derived specimen, in which a cell separating agent with thixotropic property having a specific gravity ranging from 1.050 to 1.080 and enabling the separation of tumor cells and blood cells other than the tumor cells by a centrifugal operation is housed in a bottomed tube-shaped container closed at one end and opened at the other end.

公开(公告)号：US20160223521A1

公开(公告)日：2016-08-04

申请号：US15025458

申请日：2014-09-30

Applicant: SEKISUI MEDICAL CO., LTD.

Inventor： Ryusuke Okamoto ,  Tomonori Inoue

IPC: G01N33/50 ,  G01N33/574 ,  G01N1/40

CPC classification number: G01N33/5002 ,  G01N1/4077 ,  G01N33/491 ,  G01N33/574 ,  G01N2001/4083 ,  G01N2333/70596

Abstract: To provide a device for concentration and separation of circulating tumor cells, capable of recovering circulating tumor cells in a blood-derived specimen simply, at a high recovery rate, and with low invasion of the tumor cells. A device for concentration and separation of circulating tumor cells present in a blood-derived specimen, in which a cell separating agent with thixotropic property having a specific gravity ranging from 1.050 to 1.080 and enabling the separation of tumor cells and blood cells other than the tumor cells by a centrifugal operation is housed in a bottomed tube-shaped container closed at one end and opened at the other end.

Abstract translation: 提供用于浓缩和分离循环肿瘤细胞的装置，其能够简单地以高回收率和低侵袭肿瘤细胞回收血源标本中的循环肿瘤细胞。 用于浓缩和分离存在于血液来源的标本中的循环肿瘤细胞的装置，其中具有触变性的细胞分离剂的比重范围为1.050至1.080，并且能够分离肿瘤以外的肿瘤细胞和血细胞 通过离心操作的电池容纳在一端封闭的有底管形容器中，并在另一端开口。