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    Method and system for managing feature reading and scoring in ultrasound and/or optoacoustice images
    2.
    发明授权
    Method and system for managing feature reading and scoring in ultrasound and/or optoacoustice images 有权

    公开(公告)号：US11246527B2

    公开(公告)日：2022-02-15

    申请号：US16905351

    申请日：2020-06-18

    Applicant: Seno Medical Instruments, Inc.

    Inventor： Anthony Thomas Stavros ,  Bryan Clingman ,  Sandra G. Dykes

    IPC: G06F15/18 ,  A61B5/00 ,  A61B8/00 ,  A61B8/08

    Abstract: Systems, methods and computer program products are provided for reading and scoring ultrasound and/or optoacoustic (US/OA) images that include at least one of OA images or US images acquired in connection with an examination for a region of interest (ROI). The system displays a first image that has an interior ROI outline separating an internal zone from a boundary zone. In some aspects, feature scores are obtained in connection with at least the boundary zone and peripheral zone of the first image and the feature scores are applied to a classification model to obtain at least one of a prognostic result or predictive result indicative of a trait of the lesion. In accordance with some aspects, an order in which feature scores are entered is automatically managed to obtain for the at least one of the peripheral zone or the boundary zone before the feature score is obtained for the internal zone.

    Statistical mapping in an optoacoustic imaging system
    3.
    发明授权
    Statistical mapping in an optoacoustic imaging system 有权

    公开(公告)号：US10762628B2

    公开(公告)日：2020-09-01

    申请号：US16412960

    申请日：2019-05-15

    Applicant: Seno Medical Instruments, Inc.

    Inventor： Jason Zalev ,  Bryan Clingman

    IPC: G06K9/00 ,  G06T7/00 ,  A61B8/00 ,  A61B5/145 ,  A61B5/00 ,  A61B8/08

    Abstract: Electromagnetic energy is deposited into a volume, an acoustic return signal from energy deposited in the volume is measured, and a parametric map that estimates values of at least one parameter as spatially represented in the volume is computed. A reference level of a region of interest is determined, and upper and lower color map limits are specified, with at least one of them being determined in relation to the reference level. The parametric map is then rendered in the palette of a color map by mapping the estimated values of the parametric map onto the color map according to the color map limits. Two wavelengths of energy can be applied to the volume, and the parametric map computation can be adapted by applying an implicit or explicit model of, or theoretical basis for, distribution of electromagnetic energy fluence within the volume pertaining to the two wavelengths. The actual electromagnetic energy fluence caused by each wavelength has a propensity, due to variability within the volume, to differ from the modeled or theoretical electromagnetic energy fluence.

    System and method for providing selective channel sensitivity in an optoacoustic imaging system
    4.
    发明授权
    System and method for providing selective channel sensitivity in an optoacoustic imaging system 有权

    公开(公告)号：US10517481B2

    公开(公告)日：2019-12-31

    申请号：US15207179

    申请日：2016-07-11

    Applicant: Seno Medical Instruments, Inc.

    Inventor： Jason Zalev ,  Bryan Clingman ,  Gregory Schmid

    IPC: G06K9/00 ,  A61B5/00 ,  A61B8/08 ,  A61B8/00 ,  A61B8/14

    Abstract: A method for controlling an optoacoustic imaging system includes the steps of analyzing sinogram data values to identify variations, storing information concerning the variations, generating first and second sinograms, and processing the sinograms to mitigate the effect of the variations. In the analyzing step, sinogram data values are analyzed to identify one or more variations that are related to performance of one or more of the discrete components of the optoacoustic imaging system. The identified variations are then stored. A first sinogram is generated by sampling transducer elements acoustically coupled with a surface of a volume for a predetermined period of time after delivery of a pulse of light having a first wavelength, the first sinogram containing one channel for each of the transducer elements. A second sinogram is generated by sampling the transducer elements acoustically coupled with the surface of the volume for the predetermined period of time after delivery of a pulse of light having a second wavelength, the second sinogram containing one channel for each of transducer elements. The first and second sinograms are processed using the stored information to mitigate the effect of the identified variations on the respective sinogram.

    System And Method For Mixed Modality Acoustic Sampling
    8.
    发明申请
    System And Method For Mixed Modality Acoustic Sampling 审中-公开
    混合模态声学采样系统与方法

    公开(公告)号：US20170035388A1

    公开(公告)日：2017-02-09

    申请号：US15296186

    申请日：2016-10-18

    Applicant: Seno Medical Instruments, Inc.

    Inventor： Donald G. Herzog ,  Gregory Schmid ,  Bryan Clingman ,  Jason Zalev ,  William Ackerman

    IPC: A61B8/00 ,  A61B8/08 ,  G06T7/00 ,  A61B5/00

    CPC classification number: A61B8/5292 ,  A61B5/0035 ,  A61B5/0095 ,  A61B5/0097 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4312 ,  A61B5/7225 ,  A61B5/7425 ,  A61B8/0825 ,  A61B8/4281 ,  A61B8/4416 ,  A61B8/4444 ,  A61B8/4477 ,  A61B8/4483 ,  A61B8/4494 ,  A61B8/463 ,  A61B8/5207 ,  A61B8/5215 ,  A61B8/5261 ,  G06T5/002 ,  G06T7/0012 ,  G06T7/30 ,  G06T11/003 ,  G06T2207/10132

    Abstract: Systems and methods for relaying electrical signals representing acoustic response of a volume of tissue to light and ultrasound stimulation. In an embodiment, a plurality of ultrasound transducers receive acoustic energy from the volume and generate electrical energy, which is transmitted via an electrical path to a relay system. The ultrasound transducers are operated at a wide band frequency of at least 1 MHz to 5 MHz to receive acoustic energy from the volume of tissue responsive to light stimulation and at a narrower band frequency to receive acoustic energy from the volume of tissue responsive to acoustic stimulation. The relay system relays the electrical signals to an optoacoustic system or an ultrasound instrument for further processing depending on whether the electrical signals resulted from ultrasound or light stimulation. In an embodiment, optoacoustic, ultrasound, or other images are generated from the electrical signals and may be coregistered, overlayed, or displayed.

    Abstract translation: 用于将表示一定体积的组织的声响的电信号中继到光和超声波刺激的系统和方法。 在一个实施例中，多个超声换能器从体积接收声能并产生电能，其经由电路传送到中继系统。 超声波换能器在至少1MHz至5MHz的宽频带频率下操作，以响应于光刺激从较小的频带接收来自组织的体积的声能，并且响应于声刺激从较小的频带频率接收来自组织体积的声能 。 继电器系统将电信号中继到光声系统或超声仪器以进一步处理，这取决于电信号是由超声还是光刺激引起。 在一个实施例中，光声，超声或其他图像从电信号产生，并且可以是核心的，叠加的或显示的。

    METHOD FOR DUAL MODALITY OPTOACOUSTIC IMAGING
    10.
    发明申请
    METHOD FOR DUAL MODALITY OPTOACOUSTIC IMAGING 有权
    双模态光学成像方法

    公开(公告)号：US20130301380A1

    公开(公告)日：2013-11-14

    申请号：US13667830

    申请日：2012-11-02

    Applicant: Seno Medical Instruments, Inc.

    Inventor： Alexander A. Oraevsky ,  Sergey A. Ermilov ,  Adre Conjusteau ,  Peter Brecht ,  Vyacheslav Nadvoretskly ,  Richard Su ,  Donald G. Herzog ,  Bryan Clingman ,  Jason Zalev

    IPC: A61B8/08

    CPC classification number: A61B8/5215 ,  A61B5/0035 ,  A61B5/0095 ,  A61B8/4416 ,  A61B8/4477 ,  A61B8/4494 ,  A61B8/48 ,  A61B8/481 ,  A61B8/5207 ,  A61B8/5261

    Abstract: A real-time imaging method that provides ultrasonic imaging and optoacoustic imaging coregistered through application of the same hand-held probe to generate and detect ultrasonic and optoacoustic signals. These signals are digitized, processed and used to reconstruct anatomical maps superimposed with maps of two functional parameters of blood hemoglobin index and blood oxygenation index. The blood hemoglobin index represents blood hemoglobin concentration changes in the areas of diagnostic interest relative to the background blood concentration. The blood oxygenation index represents blood oxygenation changes in the areas of diagnostic interest relative to the background level of blood oxygenation. These coregistered maps can be used to noninvasively differentiate malignant tumors from benign lumps and cysts.

    Abstract translation: 实时成像方法通过应用相同的手持式探头提供超声波成像和光声成像，以生成和检测超声波和光声信号。 这些信号被数字化，处理并用于重建与血红蛋白指数和血氧指数两个功能参数的映射叠加的解剖图。 血红蛋白指数表示相对于背景血液浓度的诊断感兴趣区域的血液血红蛋白浓度变化。 血氧指数代表诊断兴趣相对于血氧饱和度背景水平的血氧饱和度变化。 这些核心地图可用于非侵入性地区分恶性肿瘤与良性肿块和囊肿。

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