公开(公告)号：US20240262868A1

公开(公告)日：2024-08-08

申请号：US18688056

申请日：2023-02-23

申请人： SHANXI JINBO BIO-PHARMACEUTICAL CO., LTD.

发明人： Xia Yang ,  Zhenrui He

IPC分类号： C07K14/00 ,  A61K8/60 ,  C12N15/63 ,  C12P19/34

CPC分类号： C07K14/001 ,  A61K8/606 ,  C12N15/63 ,  C12P19/34 ,  C07K2319/20

摘要： Polypeptides and uses thereof are provided. The polypeptide includes an N-terminal sequence and a C-terminal sequence, wherein the N-terminal sequence includes one or more repeating units including the amino acid sequence shown in SEQ ID NO. 1. The use of a human structural material for tissue filling and augmentation is provided in the present disclosure, which is expected to have a wide range of applications in the fields such as breast augmentation, rhinoplasty and mid-face filling as it does not require transplantation from the human body, yet has the natural advantages of using human tissue for filling.

公开(公告)号：US11844880B2

公开(公告)日：2023-12-19

申请号：US17330441

申请日：2021-05-26

申请人： Sichuan University ,  Shanxi Jinbo Bio-Pharmaceutical Co., Ltd

发明人： Yunbing Wang ,  Li Yang ,  Rifang Luo ,  Lu Lu ,  Xia Yang ,  Xingdong Zhang

IPC分类号： A61L31/10 ,  B05D3/10

CPC分类号： A61L31/10 ,  B05D3/104 ,  B05D3/107 ,  A61L2300/252 ,  A61L2420/02

摘要： A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.

公开(公告)号：US20200165319A1

公开(公告)日：2020-05-28

申请号：US16698206

申请日：2019-11-27

申请人： Shanxi Jinbo Bio-Pharmaceutical Co., Ltd.

发明人： Xia Yang

IPC分类号： C07K14/78 ,  C12N15/70 ,  C07K1/14 ,  C07K1/18

摘要： The present invention relates to a polypeptide, a process for the production thereof and a use thereof. The polypeptide of the present invention has excellent adhesion effect and is highly stable in an aqueous solution. Endotoxins can be more easily removed from the product of the polypeptide.