公开(公告)号：US12241863B2

公开(公告)日：2025-03-04

申请号：US17158239

申请日：2021-01-26

Applicant: SHIMADZU CORPORATION

Inventor： Hidesato Kumagai ,  Akihiro Arai ,  Akira Harada

IPC: G01N27/447 ,  G01N27/453

Abstract: A controller sets a schedule in which an order of a plurality of electrophoresis processes is defined. The controller controls a storage device to store first information representing a result of an electrophoresis process that has ended among the plurality of electrophoresis processes and second information about setting for the plurality of electrophoresis processes. The controller receives a stop signal from an information processing apparatus while the plurality of electrophoresis processes defined in the schedule are being performed. When the controller receives the stop signal, the controller controls an electrophoresis mechanism to perform until the end, an electrophoresis process that is being performed among the plurality of electrophoresis processes. When the controller receives the stop signal, the controller maintains storage of the first information stored in the storage device and the second information on an electrophoresis process that has not yet been performed among the plurality of electrophoresis processes.

公开(公告)号：US20200211672A1

公开(公告)日：2020-07-02

申请号：US16705348

申请日：2019-12-06

Applicant: SHIMADZU CORPORATION

Inventor： Kota Ogino ,  Akira Harada ,  Hidesato Kumagai

IPC: G16B15/00

Abstract: An analyzer includes a separation data holding part, a determination criterion holding part, and a component peak determination part. The separation data holding part retains, as reference data, separation data obtained by an electrophoresis analysis for a reference sample including a reference component which is a known component and retains, as data to be analyzed, separation data obtained by an electrophoresis analysis for a sample to be analyzed. The determination criterion holding part retains a determination criterion for determining whether a component peak in the reference data and a component peak in the data to be analyzed are identical. The component peak determination part is configured to determine whether the component peak in the reference data and the component peak in the data to be analyzed are identical to each other, using the determination criterion.

公开(公告)号：US20240087188A1

公开(公告)日：2024-03-14

申请号：US18243966

申请日：2023-09-08

Applicant: SHIMADZU CORPORATION

Inventor： Kota OGINO ,  Akira Harada

IPC: G06T11/20 ,  G01N27/447 ,  G06F3/04845

CPC classification number: G06T11/206 ,  G01N27/44704 ,  G06F3/04845 ,  G06T2200/24

Abstract: An analyzer that analyzes one or more pieces of data acquired by electrophoresis separation of a sample includes a memory, a display unit, and a processor. The memory stores the one or more pieces of data. The display unit displays, based on the one or more pieces of data, a gel image, an electropherogram, a first size guide corresponding to the gel image, and a second size guide corresponding to the electropherogram. When the first size guide is located at a first position corresponding to a specific value associated with a size in the gel image, the processor displays a second size guide at a second position corresponding to the specific value in the electropherogram.

公开(公告)号：US11379974B2

公开(公告)日：2022-07-05

申请号：US16504422

申请日：2019-07-08

Applicant: SHIMADZU CORPORATION

Inventor： Hidesato Kumagai ,  Akira Harada ,  Kota Ogino

IPC: G06K9/00 ,  G06T7/00 ,  G01N27/447

Abstract: An electrophoretic separation data analyzing apparatus includes an analysis target peak identifying part configured to require a user to input analysis target peak information on analysis target peaks to be added to an analysis target in separation data obtained by electrophoretic separation, and to identify at least one of the analysis target peaks based on the analysis target peak information, a peak-of-interest identifying part configured to require the user to input peak-of-interest information on a peak of interest among the analysis target peaks, and identify the peak of interest based on the peak-of-interest information, and an abundance ratio calculating part configured to determine an abundance ratio of the peak of interest among all of the analysis target peaks based on a total value of peak areas of the analysis target peaks and a peak area value of the peak of interest.

公开(公告)号：US10996195B2

公开(公告)日：2021-05-04

申请号：US15638641

申请日：2017-06-30

Applicant: SHIMADZU CORPORATION

Inventor： Akira Harada

IPC: G01N27/447 ,  G05B23/02

Abstract: There are provided an electrophoresis measurement method which can easily and accurately judge degree of similarity between reference data and measurement target data, a data processing device, and a data processing program. Detected data obtained by subjecting a reference sample to electrophoresis is standardized with reference to peaks of a lower limit marker substance and an upper limit marker substance, and thus reference data is acquired. Detected data obtained by subjecting a measurement target sample to electrophoresis is standardized with reference to peaks of the lower limit marker substance and the upper limit marker substance, and thus measurement target data is acquired. The measurement target data is warped or shifted in a time axis direction with reference to the reference data, and corrected measurement target data is obtained.

公开(公告)号：US12216081B2

公开(公告)日：2025-02-04

申请号：US17569971

申请日：2022-01-06

Applicant: SHIMADZU CORPORATION

Inventor： Akira Harada ,  Kota Ogino ,  Hidesato Kumagai

IPC: G01N27/447

Abstract: A sample setting section in which at least one sample to be subjected to electrophoresis analysis and at least one standard sample are set, and a controller. The controller includes a standard data storage memory that stores standard data obtained by performing electrophoresis analysis of a standard sample under a predetermined condition, and a chip determination part configured to perform electrophoresis analysis of the standard sample under the predetermined condition using each of the at least one microchip before electrophoresis analysis of the sample set in the sample setting section is performed to acquire analysis data on the standard sample by the detector, and to perform a chip determination as to whether a state of each of the at least one microchip is suitable for performing electrophoresis analysis by comparing the acquired analysis data with the standard data on the standard sample.

公开(公告)号：US11791015B2

公开(公告)日：2023-10-17

申请号：US16705348

申请日：2019-12-06

Applicant: SHIMADZU CORPORATION

Inventor： Kota Ogino ,  Akira Harada ,  Hidesato Kumagai

IPC: G16B15/00

CPC classification number: G16B15/00

Abstract: An analyzer includes a separation data holding part, a determination criterion holding part, and a component peak determination part. The separation data holding part retains, as reference data, separation data obtained by an electrophoresis analysis for a reference sample including a reference component which is a known component and retains, as data to be analyzed, separation data obtained by an electrophoresis analysis for a sample to be analyzed. The determination criterion holding part retains a determination criterion for determining whether a component peak in the reference data and a component peak in the data to be analyzed are identical. The component peak determination part is configured to determine whether the component peak in the reference data and the component peak in the data to be analyzed are identical to each other, using the determination criterion.

公开(公告)号：US20230304966A1

公开(公告)日：2023-09-28

申请号：US18171811

申请日：2023-02-21

Applicant: Shimadzu Corporation

Inventor： Kota Ogino ,  Akira Harada

IPC: G01N27/447 ,  G01N1/40

CPC classification number: G01N27/44717 ,  G01N1/4005 ,  G01N27/44782 ,  G01N2001/4038

Abstract: A display method for displaying a plurality of pieces of data respectively obtained by electrophoretic separation for a plurality of samples. The first data includes a first peak corresponding to a separated component of the known sample. The second data includes a second peak corresponding to a separated component of the unknown sample. The display method includes: acquiring the plurality of pieces of data; detecting the first peak and the second peak respectively from the first data and the second data; setting a range included within a predetermined threshold from the first peak as a specified range; determining, for the second data, whether or not the second peak is included in the specified range; and displaying specifically the second peak, when the second peak is in the specified range.