公开(公告)号：US12097479B2

公开(公告)日：2024-09-24

申请号：US17044393

申请日：2018-12-28

Applicant: SHIMADZU CORPORATION

Inventor： Tadayuki Yamaguchi ,  Daiki Fujimura ,  Hideyuki Otsuki

IPC: B01J20/10 ,  B01J20/24 ,  B01J20/28 ,  B01J20/281 ,  B01J20/286 ,  B01J20/288 ,  G01N30/16 ,  G01N30/72

CPC classification number: B01J20/103 ,  B01J20/24 ,  B01J20/28052 ,  B01J20/286 ,  B01J20/288 ,  G01N30/16 ,  G01N30/7233 ,  B01J2220/46 ,  B01J2220/54

Abstract: A separating column (12) for hippuric acid analysis is filled with a filler in which 123 μmol/g or more of β-cyclodextrin is chemically bonded to a silica matrix. By using such a filler for the separating column (12) in which 123 μmol/g or more of β-cyclodextrin is chemically bonded to the silica matrix, hippuric acid, o-methyl hippuric acid, m-methyl hippuric acid, p-methyl hippuric acid, and mandelic acid can be separated without using a mobile phase containing cyclodextrin.