公开(公告)号：US20200324272A1

公开(公告)日：2020-10-15

申请号：US16811329

申请日：2020-03-06

Applicant: SHIMADZU CORPORATION

Inventor： Yukio OIKAWA ,  Shigeyoshi HORIIKE ,  Hirotaka KOYAMA

IPC: B01J20/287 ,  C07F7/08 ,  B01J20/22 ,  B01J20/28 ,  B01J20/291 ,  B01J20/32 ,  B01J20/30 ,  B01D15/20 ,  B01D15/32

Abstract: The present invention provides a method for hydrophobization of a hydrophilic material, the method including introducing a hydrophobic group into a hydroxyl group (—OH group) on a surface of the hydrophilic material. A method for hydrophobization of a hydrophilic material, the method comprising reacting a hydrophilic material to be hydrophobized with a hydrophobic group-containing silylating agent in presence of an amino acid as a reaction accelerator, to introduce a hydrophobic group-containing silyl group to a surface of the hydrophilic material. A hydrophobized silica gel column filler is produced by using the method. Further, a hydrophobized silica gel column is produced by filling a column with the hydrophobized silica gel column filler.