公开(公告)号：US20210138482A1

公开(公告)日：2021-05-13

申请号：US17046510

申请日：2018-04-11

Applicant: SHIMADZU CORPORATION

Inventor： Shigeyoshi HORIIKE ,  Jun YANAGIBAYASHI ,  Yukio OIKAWA ,  Maiko NAKAYA ,  Masaki KANAI

IPC: B03B5/62 ,  G01N1/10

Abstract: A field-flow fractionation device includes a separation channel, a carrier fluid supplier, a separation membrane, a waste liquid chamber, a cross-flow flow rate adjuster, and a carrier fluid adder. The carrier fluid adder is configured to add, to a flow of a carrier fluid having passed through the separation membrane, a flow of another carrier fluid at a carrier fluid adding position set on an upstream side of the cross-flow flow rate adjuster so that the flow rate of the carrier fluid flowing into the cross-flow flow rate adjuster is larger than the flow rate of the carrier fluid having passed through the separation membrane.

公开(公告)号：US20210372972A1

公开(公告)日：2021-12-02

申请号：US16334469

申请日：2017-09-14

Applicant: SHIMADZU CORPORATION

Inventor： Yukio OIKAWA ,  Shigeyoshi HORIIKE ,  Maiko NAKAYA ,  Masaki KANAI

IPC: G01N30/00 ,  B03B5/62

Abstract: Field flow fractionation device includes a channel switching unit for switching the connection of a second carrier fluid supply unit to any one of the second inlet port of an upper separation cell, the first inlet port of a lower separation cell, or the second inlet port of a lower separation cell. Furthermore, the second carrier fluid supply unit is connected to the second inlet port of an upper separation cell during the process of focusing to generate flow of carrier fluid counter to the flow of carrier fluid from the first inlet port within the upper separation cell, whereas the second carrier fluid supply unit is connected to the first inlet port or the second inlet port of a lower separation cell after conclusion of focusing in the upper separation cell.

公开(公告)号：US20210299675A1

公开(公告)日：2021-09-30

申请号：US17260372

申请日：2019-07-05

Applicant: SHIMADZU CORPORATION

Inventor： Shigeyoshi HORIIKE ,  Yukio OIKAWA ,  Maiko NAKAYA

IPC: B03B5/62 ,  B01L3/00

Abstract: A separation cell includes a separation channel forming chip and a discharge channel forming chip. The separation cell includes a separation channel forming plate that is provided on the separation channel forming chip and has a flat surface defining a separation channel having a longitudinal direction, a discharge channel forming plate that is provided on the discharge channel forming chip and has a flat surface defining a discharge channel extending along a longitudinal direction of the separation channel, a separation membrane that is provided on the flat surface defining the separation channel on the separation channel forming chip, and is for selectively allowing a carrier fluid to permeate, a porous support plate and is attached to block an opening of the discharge channel, and a positioning structure for positioning the separation channel forming chip and the discharge channel forming chip in a specific geometrical relationship with respect to each other.