公开(公告)号：US20220401312A1

公开(公告)日：2022-12-22

申请号：US17692568

申请日：2022-03-11

Applicant: SHOFU INC.

Inventor： Kenzo YAMAMOTO ,  Hideto KASABA ,  Daisuke HARA ,  Shunsuke MIYATA

IPC: A61K6/896 ,  A61C5/00 ,  A61K6/76 ,  A61K6/62

Abstract: [Problem]
To provide a dental photocurable composition which has sufficient mechanical property and whose rheological property is not deactivated even after long-term storage.
[Solution]
The dental photocurable composition of the present disclosure comprises (A) polymerizable monomer, (B) photosensitizer, (D) photopolymerization accelerator and (E) filler, wherein, the dental photocurable composition comprises (D1) aliphatic tertiary amine compound represented by formula (1) as the (D) photopolymerization accelerator, and the dental photocurable composition comprises (E1) hydrophobized silica fine particle having an average diameter of primary particle of 1 to 40 nm as the (E) filler. (wherein R1 represents a substituent consisting of three or more carbons having an electron-withdrawing group at α-carbon and/or ε-carbon of an amine starting from N, R2 represents a substituent consisting of three or more carbons which may have an electron-withdrawing group, R3 represents a substituent consisting of one or more carbons which may have an electron-withdrawing group, and α-carbon of N in the formula (1) is not an electron-withdrawing group.)

公开(公告)号：US20220387263A1

公开(公告)日：2022-12-08

申请号：US17692584

申请日：2022-03-11

Applicant: SHOFU INC.

Inventor： Naoya KITADA ,  Rei NISHIMURA ,  Daisuke HARA ,  Kenzo YAMAMOTO

IPC: A61K6/896 ,  A61K6/62 ,  A61K6/76 ,  A61K6/17

Abstract: To provide a dental photocurable composition having good storage stability of a matrix containing a polymerizable monomer and a polymerization initiator, etc. and excellent mechanical strength of a dental photocurable composition comprising a mixture of the matrix and a filler. The dental photocurable composition of the present disclosure comprises a matrix containing (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator and (D) photopolymerization accelerator, and (E) filler, wherein, the dental photocurable composition comprises (A1) polymerizable monomer having an acidic group as the (A) polymerizable monomer, and the dental photocurable composition comprises (D1) tertiary aliphatic amine compound having Log P of 2 or more and pKa of 10 or less as the (D) photopolymerization accelerator.

公开(公告)号：US20210189098A1

公开(公告)日：2021-06-24

申请号：US17032284

申请日：2020-09-25

Applicant: SHOFU INC.

Inventor： Daisuke HARA ,  Kenzo YAMAMOTO ,  Yasuhiro NISHINO ,  Kazuya SHINNO

IPC: C08K5/00 ,  C08F220/12 ,  C08K9/06 ,  C08K3/40 ,  C08K5/1575 ,  C08K9/02 ,  C08K3/16 ,  C08K3/11 ,  C08K3/22 ,  C08K3/30 ,  C08K3/36 ,  C08L33/12

Abstract: To provide a dental curable composition having excellent curability and storage stability. The dental curable composition contains(a) transition metal adsorbent in which a transition metal compound of the period 4 in the periodic table is adsorbed on an inorganic particle which is non-reactive with a transition metal of the period 4 in the periodic table, (b) thiourea derivative, (c) organic peroxide having a hydroperoxide group, and (d) polymerizable monomer, wherein the (d) polymerizable monomer contains (d-1) acidic group-non-containing polymerizable monomer, and wherein a pore volume of the inorganic particle which is non-reactive with a transition metal of the period 4 in the periodic table is 0.2 cc/g or less.

公开(公告)号：US20220387264A1

公开(公告)日：2022-12-08

申请号：US17692598

申请日：2022-03-11

Applicant: SHOFU INC.

Inventor： Shunsuke MIYATA ,  Kenzo YAMAMOTO ,  Daisuke HARA

IPC: A61K6/896 ,  A61K6/62 ,  A61K6/71 ,  A61K6/77 ,  A61K6/76

Abstract: [Problem]
To provide a dental curable composition having good mechanical property and good storage stability before and after curing.
Solution
The dental curable composition of the present disclosure comprises (A) polymerizable monomer, (BC) polymerization initiator, (D) polymerization accelerator and (E) filler, wherein, the (BC) polymerization initiator comprises (B) photopolymerization initiator and/or (C) chemical polymerization initiator, the (B) photopolymerization initiator comprises (B1) photosensitizer and (B2) photoacid generator, the (C) chemical polymerization initiator comprises (C1) organic peroxide, the (E) filler comprises (E1) surface-treated basic filler, and the (E1) surface-treated basic filler is treated with (F1) surface treatment agent represented by the formula (1) and/or condensate thereof. [Formula (1)] MXn  [Chemical formula 1] (In the formula, M is a metal atom selected from Si, Ti, Zr, and Al, X is H, OH or a hydrolyzable group, and may be the same or different from each other. In the case that M is Si, Ti or Zr, n is 4. In the case that M is Al, n is 3.)

公开(公告)号：US20220287921A1

公开(公告)日：2022-09-15

申请号：US17201180

申请日：2021-03-15

Applicant: SHOFU INC.

Inventor： Kenzo YAMAMOTO ,  Hideto KASABA ,  Daisuke HARA ,  Shunsuke MIYATA

IPC: A61K6/62 ,  A61K6/71 ,  A61K6/78

Abstract: [Problem]
To provide a dental photocurable composition having sufficient mechanical property and being excellent in color tone selectivity because of having a small color difference between before curing and after curing.
[Solution]
To provide a dental photocurable composition, comprising (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator, (D) photopolymerization accelerator and (E) filler, wherein, the dental photocurable composition comprises (B-1) α-diketone compound as the (B) photosensitizer, and the dental photocurable composition comprises, with respect to 100 parts by mass of the (A) polymerizable monomer, 0.15 parts by mass or less of the (B-1) α-diketone compound, 0.5 parts by mass or more of the (C) photoacid generator, and 100 parts by mass or more of the (E) filler.

公开(公告)号：US20220287920A1

公开(公告)日：2022-09-15

申请号：US17201165

申请日：2021-03-15

Applicant: SHOFU INC.

Inventor： Kenzo YAMAMOTO ,  Daisuke HARA ,  Shunsuke MIYATA

IPC: A61K6/62 ,  A61K6/887

Abstract: To provide a dental photocurable composition which can exhibit excellent mechanical characteristics even after returning from a low temperature to room temperature.
To provide a dental photocurable composition, comprising (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator and (D) photopolymerization accelerator and the (C) photoacid generator may include only (C-1) iodonium salt-based compound of an anion having log S of −4 or less.

公开(公告)号：US20200214819A1

公开(公告)日：2020-07-09

申请号：US16575867

申请日：2019-09-19

Applicant: SHOFU INC.

Inventor： Daisuke HARA ,  Naoya KITADA ,  Kenzo YAMAMOTO ,  Yasuhiro NISHINO ,  Yoshiyuki JOGETSU

IPC: A61C19/10

Abstract: [Problem]To select a dental cement or a trial test material for easily obtaining high color tone adaptability to peripheral tooth substances, in mounting of or trial test of a prosthesis device[Solution]To provide a dental cement set consisting of a plurality of dental cements having color tones including color tones of 3 to n colors for selecting and using a dental cement from the plurality of dental cements having the color tones including the color tones of the 3 to n colors after trial test with trial test materials for the dental cement to be used from the plurality of dental cements having the color tones including the color tones of the 3 to n colors, wherein: the amount of information loss Pin with regard to first principal component determined by principal component analysis is less than 2, and . the dental cement set satisfies following Formula 1. 2≤((CL*p−1−CL*p)2 +(Ca*p−1−Ca*p)2 +(Cb*p−1−Cb*p)2)1/2

公开(公告)号：US20250064686A1

公开(公告)日：2025-02-27

申请号：US18731785

申请日：2024-06-03

Applicant: SHOFU INC

Inventor： Shunsuke Miyata ,  Akiko MATSUMOTO ,  Kenzo YAMAMOTO

IPC: A61K6/15

Abstract: To provide a dental curable composition having excellent solubility of an ultraviolet absorber, sunlight stability, fluorescence property, and mechanical property.
To provide a dental curable composition comprising, (A) polymerizable monomer, (B) polymerization initiator, (C) fluorescent agent, and (D) ultraviolet absorber, wherein, the dental curable composition comprises, as the (D) ultraviolet absorber, (D-1) compound having at least one first absorption maximum in the wavelength region of 250 to 320 nm and at least one second absorption maximum in the wavelength region of 320 to 400 nm, wherein the ratio of an absorbance of the first absorption maximum to an absorbance of the second absorption maximum is within the range of 1 to 4.

公开(公告)号：US20220287919A1

公开(公告)日：2022-09-15

申请号：US17201118

申请日：2021-03-15

Applicant: SHOFU INC.

Inventor： Kenzo YAMAMOTO ,  Hiroyuki KOBAYASHI ,  Daisuke HARA ,  Shunsuke MIYATA

IPC: A61K6/62 ,  C08K5/00 ,  C08K5/14 ,  C08F220/32 ,  C08F220/28 ,  C08F2/50 ,  C08K5/17 ,  C08K5/08 ,  A61K6/61 ,  A61K6/887

Abstract: [Problem]
To provide a photocurable composition having a high curing depth.
[Solution]
To provide a photocurable composition of the present disclosure comprises (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator, and (D) photopolymerization accelerator, wherein, the photocurable composition comprises (D-1) amine compound represented by formula (1) as the (D) photopolymerization accelerator. (In the formula (1), R1 is a substituent represented by formula (2), and R2 and R3 are substituents represented by formula (2) or substituents selected from —OH group, —O— group, —S— group, —NH—C(O)—NH— group, —C(O)—O— group, —OC(O)— group, —OC(O)—NH— group, —NH—C(O)—O— group, halogen, an organic group which may have an alkoxysilyl group, an aromatic ring which may have a substituent and an alicyclic heterocycle which may have a substituent. Further, R2 and R3 may be H when at least one or more R4s of the formula (2) are an aromatic ring, and R3 may be H when R2 is a substituent represented by the formula (2).)

公开(公告)号：US20220287918A1

公开(公告)日：2022-09-15

申请号：US17201150

申请日：2021-03-15

Applicant: SHOFU INC.

Inventor： Kenzo YAMAMOTO ,  Daisuke HARA ,  Shunsuke MIYATA

IPC: A61K6/30 ,  A61K6/62 ,  A61K6/831

Abstract: [Problem]
To provide a dental adhesive composition having excellent storage stability and adhesive strength.
[Solution]
To provide a dental adhesive composition, comprising (A) polymerizable monomer, (D) photopolymerization accelerator, and (F) volatile organic solvent, wherein, the dental adhesive composition comprises (A-1) polymerizable monomer having an acidic group as the (A) polymerizable monomer, and the dental adhesive composition comprises (D-1) aliphatic tertiary amine compound represented by formula (1) as the (D) photopolymerization accelerator. (wherein R1 represents a substituent consisting of three or more carbons having an electron-withdrawing group at α-carbon and/or β-carbon of an amine starting from N, R2 represents a substituent consisting of three or more carbons which may have an electron-withdrawing group, R3 represents a substituent consisting of one or more carbons which may have an electron-withdrawing group, and α-carbon of N in the formula (1) is not an electron-withdrawing group.)