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公开(公告)号:US10774037B2
公开(公告)日:2020-09-15
申请号:US16320686
申请日:2017-07-25
Applicant: SHOWA DENKO K.K.
Inventor: Takanori Aoki , Akira Shibuya , Takamitsu Kobayashi , Hideo Miyata , Shinya Tsukamoto , Manabu Kuwajima , Motoki Murai
IPC: C07C227/18 , C07C323/58 , C07C229/08 , C07C319/12 , B01J23/745 , B01J23/10 , B01J31/00 , C07C319/20 , B01J23/06 , B01J21/06 , C07C231/02 , C07C233/04
Abstract: The present invention relates to a method for producing a specified α-amino acid, the method including allowing a specified α-amino acid amide and water to react with each other in the presence of a zirconium compound which contains zirconium and at least one metal element selected from the group consisting of lithium, nickel, copper, zinc, cesium, barium, hafnium, tantalum, cerium, and dysprosium.
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公开(公告)号:US11453648B2
公开(公告)日:2022-09-27
申请号:US17291662
申请日:2019-11-07
Applicant: SHOWA DENKO K.K.
Inventor: Motoki Murai , Akira Shibuya
IPC: C07D239/557 , C07D239/545
Abstract: Provided is a method for producing an orotic acid derivative, the method comprising a condensation step of performing, under a basic condition, a condensation reaction between an orotic acid halide represented by General Formula (I) and a compound represented by General Formula (II) to generate an orotic acid derivative represented by General Formula (III); and a neutralization crystallization step of precipitating crystals of orotic acid by neutralization crystallization to separate a liquid containing the orotic acid derivative from the crystals of orotic acid, after the condensation step. In General Formula (I), (II), or (III), X is a halogen atom, and A is a group represented by General Formula (A-1) or (A-2). In General Formula (A-1) or (A-2), R1 is a hydrogen atom or an organic group, and R2 and R3 are each independently an organic group. In a case where R1 is an organic group, R1 and R2 may be bonded to each other to form a ring.
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公开(公告)号:US11319278B2
公开(公告)日:2022-05-03
申请号:US16317988
申请日:2017-07-11
Applicant: SHOWA DENKO K.K.
Inventor: Takanori Aoki , Akira Shibuya , Takamitsu Kobayashi , Hideo Miyata , Shinya Tsukamoto , Manabu Kuwajima , Motoki Murai
IPC: C07C227/26
Abstract: Provided is a method for producing glycine, in which on synthesizing glycine from glycinonitrile, glycine can be obtained in a higher yield than that in the conventional method. The present invention relates to a method for producing glycine, including allowing glycinonitrile and water to react with each other in the presence of a cerium compound, optionally adding ammonia thereto, to obtain glycine.
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