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公开(公告)号:US20220056043A1
公开(公告)日:2022-02-24
申请号:US17416064
申请日:2020-02-10
发明人: GUIYING LI , Zejin YOU , Yun HE , Qiang TIAN , Hongmei SONG , Tongtong XUE , Jingyi WANG
IPC分类号: C07D495/04 , A61P35/00
摘要: The present invention relates to a nitrogen-containing fused ring compound, a preparation method and use thereof. Specifically, the present invention relates to a compound having the structure of Formula (X), a stereoisomer, tautomer or mixture thereof, a pharmaceutically acceptable salt, co-crystal, polymorph or solvate thereof, or a stable isotope derivative, metabolite or prodrug thereof. The compound of the invention may have the structure of Formula (I) or Formula (II). These compounds are useful for the treatment of an abnormal cell proliferation disease (e.g., cancer).