公开(公告)号：US20230027684A1

公开(公告)日：2023-01-26

申请号：US17391356

申请日：2021-08-02

Applicant: Skyhawk Therapeutics, Inc.

Inventor： Michael LUZZIO ,  Brian LUCAS ,  Daniel Brian HORNE

IPC: C07D471/08 ,  C07D519/00

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, pharmaceutical compositions comprising the same, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US20230054781A1

公开(公告)日：2023-02-23

申请号：US17388093

申请日：2021-07-29

Applicant: Skyhawk Therapeutics, Inc.

Inventor： Michael LUZZIO ,  Brian LUCAS

IPC: C07D451/14 ,  C07D451/06 ,  C07D519/00

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, pharmaceutical compositions comprising the same, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US20230020922A1

公开(公告)日：2023-01-19

申请号：US17391620

申请日：2021-08-02

Applicant: Skyhawk Therapeutics, Inc.

Inventor： Michael LUZZIO ,  Brian LUCAS

IPC: C07D471/08

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

公开(公告)号：US20230008867A1

公开(公告)日：2023-01-12

申请号：US17391479

申请日：2021-08-02

Applicant: SKYHAWK THERAPEUTICS, INC.

Inventor： Michael LUZZIO ,  Brian LUCAS ,  Daniel Brian HORNE ,  Tiansheng WANG

IPC: C07D471/08 ,  C07D519/00

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.