公开(公告)号：US12156946B2

公开(公告)日：2024-12-03

申请号：US17016528

申请日：2020-09-10

Applicant: SOL-GEL TECHNOLOGIES LTD.

Inventor： Ofer Toledano ,  Haim Bar-Simantov ,  Nissim Bilman ,  Leora Shapiro ,  Raed Abu-Reziq ,  Hanan Sertchook

IPC: A61K9/50 ,  A01N25/26 ,  A01N53/00 ,  A61K8/11 ,  A61K8/25 ,  A61K8/38 ,  A61K8/67 ,  A61Q19/00 ,  B01J13/02 ,  B01J13/22 ,  C09C3/06

Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.

公开(公告)号：US20210007996A1

公开(公告)日：2021-01-14

申请号：US17016528

申请日：2020-09-10

Applicant: SOL-GEL TECHNOLOGIES LTD.

Inventor： Ofer TOLEDANO ,  Haim Bar-Simantov ,  Nissim Bilman ,  Leora Shapiro ,  Raed Abu-Reziq ,  Hanan Sertchook

IPC: A61K9/50 ,  C09C3/06 ,  A61K8/11 ,  A61Q19/00 ,  A61K8/67 ,  B01J13/02 ,  A01N25/26 ,  B01J13/22 ,  A61K8/38 ,  A01N53/00 ,  A61K8/25

Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.